Product Name: 11Beta,21-Dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
Chemical Name: 21-Acetoxy-11β,21-dihydroxy-pregna-1,4,16-triene-3,20-dione
Synonyms: Not widely known by trade names; reference to structural name for inquiries
CAS Number: 53934-48-2
Use: Research chemical, possible intermediate in steroid chemistry
Manufacturer: Supplier or institution details per purchase documentation
Emergency Phone: National Poison Control Center or local emergency services for chemical incidents
GHS Classification: Not fully classified due to limited commercial availability; potential hazards based on steroidal structure
Pictogram: Not typically assigned; use standard corrosive or irritant sign if unsure
Signal Word: Warning
Hazard Statements: May cause skin or eye irritation, may interfere with hormonal balance in case of prolonged exposure, inhalation or ingestion may result in respiratory or gastrointestinal symptoms
Precautionary Statements: Avoid contact with skin and eyes; avoid inhalation of dust or vapors; use minimum practical quantities; strict laboratory hygiene
Potential Health Effects: Skin or eye exposure may cause localized irritation or allergic reaction; inhalation may cause coughing, dizziness or mild respiratory symptoms; accidental ingestion could disrupt endocrine pathways
Specific Target Organ Toxicity: No detailed data; possible impact on hormonal organs with chronic exposure
Chemical Identity: 11Beta,21-Dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
Concentration: Purity typically exceeds 95% in laboratory samples
Impurities: Small amounts of related steroidal compounds, residual solvents from synthesis
Molecular Formula: C23H28O6
Molecular Weight: 400.46 g/mol
Inhalation: Move affected individual out of exposure to fresh air; monitor breathing and seek medical advice if symptoms develop (shortness of breath, persistent cough, dizziness)
Skin Contact: Remove contaminated clothing; wash skin with copious amounts of water and mild soap for 15 minutes, seek medical attention for rash or irritation
Eye Contact: Rinse eyes with flowing lukewarm water for at least 15 minutes, lifting eyelids to ensure thorough irrigation; seek prompt medical evaluation for pain or redness
Ingestion: Do not induce vomiting; rinse mouth; provide water to drink if alert; seek immediate medical attention for unusual symptoms or concerns about hormonal effects
Indication for Medical Attention: Persistent redness, altered consciousness, or signs of toxicity should trigger review by healthcare professionals with chemical exposure experience
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam
Fire Hazards: Combustion may release carbon monoxide, carbon dioxide, acrid smoke, and possible traces of steroids or organic acids
Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus
Special Precautions: Minimize run-off from firefighting as contaminated water can carry the chemical beyond the immediate site
Unusual Fire Hazards: Dusts may form explosive mixtures with air under specific conditions, although this is unlikely at laboratory scales
Personal Precautions: Wear gloves, lab coat, and protective eyewear; use respiratory protection if dust is generated
Environmental Precautions: Prevent spread to drains, surface water, or soil; contain spill using absorbent materials suited for organic solvents
Cleanup Methods: Scoop up solids without raising dust; wash contaminated area with water and detergent; dispose of cleanup materials as hazardous waste
Notification Procedures: For significant spills, inform environmental health and safety resources at the institution or notify local regulatory agencies
Handling: Operate in a fume hood or ventilated space to avoid inhaling dust; wear nitrile gloves, safety glasses, and lab clothing; minimize direct handling
Storage: Keep in tightly sealed bottles away from light, moisture, and direct heat; place container in flammables cabinet if possible; segregate from food items and incompatible chemicals
Incompatibilities: Strong oxidizers, acids, and bases can react with the compound, potentially leading to degradation or hazardous byproducts
Other Precautions: Label all containers clearly; keep unused material under lock to avoid accidental misuse
Engineering Controls: Standard laboratory ventilation, use of fume hoods or glove boxes for weighing and transfer
Personal Protective Equipment: Chemical-resistant gloves (nitrile or equivalent), safety goggles, laboratory coat; use dust mask or higher protection if airborne dust anticipated
Hygiene Measures: Avoid eating, drinking, or smoking in work areas; wash hands thoroughly after handling; remove contaminated clothing before leaving workspace
Exposure Limits: No occupational exposure values established for this compound, practice strict avoidance of unnecessary exposure
Appearance: Off-white to pale yellow powder or crystalline solid
Odor: Faint, non-characteristic
Melting Point: Estimated in the range of 210–225°C (some variation depending on sample purity)
Boiling Point: Not detected before decomposition
Solubility: Slightly soluble in ethanol, DMSO, chloroform; limited solubility in water
Vapor Pressure: Negligible at standard conditions
Density: Approx. 1.3 g/cm³ (estimation)
pH: Not applicable (solid)
Partition Coefficient (log Kow): Not measured, moderate lipophilicity likely based on structure
Viscosity: Not relevant for solid forms
Chemical Stability: Stable under standard laboratory conditions, sensitive to extended exposure to light, heat, or acids/bases
Hazardous Reactions: Contact with strong oxidizing agents may trigger decomposition; possible liberation of acetic acid or breakdown to related steroidal compounds
Decomposition Products: Carbon oxides, acetic acid, trace organic residues
Conditions to Avoid: Moisture, high temperatures, UV light, strong acids and oxidizers
Polymerization: Not expected to occur
Acute Toxicity: No animal data published; similarity to corticosteroid analogs suggests low acute toxicity at sub-milligram exposures
Skin/Eye Irritation: Irritation possible upon contact; steroidal compounds sometimes provoke mild dermatitis or conjunctivitis
Sensitization: Possible primer for allergic responses in genetically susceptible individuals after repeat exposure
Chronic Toxicity: Sustained repeated exposure could influence hormonal balance or immune function
Mutagenicity/Carcinogenicity: Not evaluated for this compound; reference to general steroid toxicology points to minimal genotoxic potential at laboratory scales
Signs and Symptoms of Exposure: Cough, mild respiratory distress, skin rash, possible mood alterations with absorption
Ecotoxicity: Data not available, but steroid compounds can affect aquatic life at significant concentrations
Persistence and Degradability: Moderate; steroid ring structure resists rapid environmental degradation
Bioaccumulation Potential: Likely to be taken up by organisms due to lipophilic nature
Mobility in Soil: Low to moderate adsorption to soil particles
Other Adverse Effects: Sub-acute, non-lethal effects possible to aquatic and soil organisms if released in bulk quantities
Waste Treatment Methods: Chemical must go through high-temperature incineration as hazardous organic material
Disposal of Containers: Rinse and dispose as controlled chemical waste, do not reuse for other substances
Sewage Disposal: Never pour down the drain; notify environmental authorities if accidental release occurs
Precautions: Follow institutional and national regulations for disposal, keep records of all chemical disposals for compliance
UN Number: Not assigned for this research compound
Proper Shipping Name: Laboratory chemical, not otherwise specified
Transport Hazard Class: Not regulated for road, rail, air, or sea unless shipped in significant quantity
Packing Group: Not assigned
Environmental Hazards: Caution for accidental spills, especially near water bodies
Special Precautions for User: Use sealed secondary containment, label packages clearly, restrict to professional transport if moving between sites
Inventory Status: Not listed in U.S. TSCA, EU REACH, or major international chemical inventories; considered a research chemical
Federal and State Regulations: Not scheduled as a controlled substance in most jurisdictions
Workplace Safety: General chemical safety practices required as per OSHA, COSHH, or local laboratory safety codes
Labeling Requirements: Must include full chemical name, date of acquisition, hazard warnings, and responsible party details
Other Legal Restrictions: Use limited to trained personnel within research or testing laboratories; export or distribution may trigger additional regulatory review based on destination country
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