Chemistry has come a long way from the early days of trial-and-error experimentation in dimly lit labs. The story of 16-Alpha-Methyl Epoxide started with the search for steroid derivatives and small organic molecules that could help researchers fine-tune drug design. Back in the mid-20th century, scientists were enthralled by the idea that slight tweaks to core steroid structures might unlock new therapeutic benefits. Researchers using basic glassware and limited analysis tools pushed the boundaries, often relying on their instincts and a bit of good fortune to separate and characterize novel compounds. In those formative years, producing 16-Alpha-Methyl Epoxide required laborious extraction and purification from multi-step steroid transformations. Recent decades gave way to precision and higher yields, anchored by improvements in catalytic epoxidation and better analytical techniques. Now, development cycles are much shorter. Organic chemists routinely build libraries of derivatives in high-throughput setups, expanding what’s possible, not just in pharmaceuticals but also in agricultural and materials science.
On my bench, 16-Alpha-Methyl Epoxide sits as a crystalline white powder—unremarkable at first glance, but it holds a mighty punch. For a long time, drug designers and academic researchers viewed this molecule as a launching pad. Its value doesn’t simply rest in the structure itself, but in the myriad transformations it supports. It ends up in small vials, often stabilized under nitrogen yet shipped worldwide for lab and pilot-scale projects. The product often reaches customers with thorough documentation, lot-to-lot consistency checks, and guidance that touches on every aspect from storage conditions to expiration windows. Laboratories gratefully build upon its reliability, and industry leans on it for ways to efficiently probe structure-activity relationships. I remember those first runs, troubleshooting temperature controls and watching crystals form on cold glass. It drove home how much work happens behind the scenes, long before findings show up on journal pages.
The molecule packs into a tight crystalline lattice, melting at moderate temperatures and showing little volatility. 16-Alpha-Methyl Epoxide doesn’t dissolve well in water—a fact that shapes how chemists approach formulation and drug delivery. It laughs off mild acids and bases, but the strained epoxide ring brings a special reactivity profile. That small three-membered oxygen ring makes it ready for attack. I’ve seen firsthand how even a brief exposure to nucleophilic solvents can change its fate. Its density and solubility force operators to respect standard operating procedures, and those following green chemistry prefer it because the byproducts of transformations often prove easy to manage. Strong odors don’t announce its presence, so responsible handling means trusting your process and your analytical gear instead of your senses.
Every bottle tells a story, starting with purity thresholds, batch ID, retest periods, and storage temperature. The technical document lists melting point, moisture content, HPLC area normalization data, and residual solvent levels. Sometimes departing from standard protocols leads to surprises—like shifts in melting point due to polymorph formation. Quality teams scan every lot with NMR and mass spec to confirm nobody snuck in closely related isomers. Labels carry hazard statements and pictograms, signaling operators to glove up and avoid accidental skin contact. Proper documentation and handling instructions prove essential for new hires in fast-paced labs, reducing the chance of ruined batches and lost time.
Production often starts from established steroids or their methylated counterparts. The most common route uses peracid epoxidation on the 16-Alpha-Methyl derivative. Timing, temperature, and order of addition play outsized roles. I’ve spent nervous hours by the fume hood, adjusting dropwise additions, recording color shifts, and sampling for TLC. Standard workups involve quenching unreacted peracid, washing, and then purifying through column chromatography. Yields fluctuate more than anyone would like, with subtle factors like glassware cleanliness or batch-to-batch quality of starting steroids making a real difference. Scaling up for industry means tackling heat transfer, mixing, and purification bottlenecks that remain invisible at bench scale.
Hands-on work reveals 16-Alpha-Methyl Epoxide as deceptively reactive. A basic nucleophile seeks out that electrophilic ring, opening it to give alcohols or ethers. Transition-metal catalysis lets teams tack on new substituents across the epoxide or even do ring contractions. I recall long nights, measuring conversion rates, pushing the boundaries of regio- and stereo-selectivity. Modifications unlock analogs with unique biological profiles. Some chemists target a protected alcohol function, using the epoxide as a precursor; others leap right for rearrangements to make new chiral centers. Each approach gives rise to libraries of derivatives that have shaped antiviral, anti-inflammatory, and hormone-related research pipelines for decades.
On the shelf, it often carries synonyms such as 16α-Methyl-17α-epoxyandrostane or 16-Methyl Epoxyandrostane. Older books may record it as a methylated steroid epoxide or just shorten it to “16-ME Epoxide.” Chemical vendors sometimes list proprietary codes or abbreviations, so lab notebook entries and procurement ledgers bristle with alternate titles. Ordering can get tangled if you overlook these differences, especially for international shipping and custom synthesis requests. Precision saves hours, as I once learned the hard way, when a mislabelled shipment delayed an entire project cycle.
Working with steroids and epoxides means playing close attention to safety culture. Gloves, eye protection, and fume hoods are not optional—they become second nature. Each operator reviews the specific material safety data sheet, which currently highlights the potential for skin sensitization, pinpoints inhalation hazards, and notes the need for spill management. Regulatory teams draft operating procedures to keep waste out of the general trash and guide first responders in case of accidental exposure. Emergency shower sites and eyewash fountains serve as simple reminders that every shift can bring new surprises when handling reactive organics. Routine monitoring of workspaces, strong ventilation, and in-depth training prove their value every time someone brings a new team member on board.
Pharmaceutical researchers value the epoxide group’s ability to act as a versatile intermediate. Medicinal chemists lean on 16-Alpha-Methyl Epoxide for potent derivatives targeting steroid receptors, anti-cancer compounds, or investigative tools for probing metabolic pathways. In my time supporting clinical pipeline development, we hit milestones using its ring system for selective functionalization—giving drugs just the right balance of potency and metabolic stability. Academic labs, meanwhile, use it as a probe in mechanistic organometallic studies and asymmetric catalysis, often pushing method development for synthetic organic chemistry. The agri-products sector probes its potential as a scaffold for new hormone mimics and pest control agents.
Each year, scientific publications add dozens of new entries covering modifications, improved preparative methods, and structure-function insight born from 16-Alpha-Methyl Epoxide. As part of collaborative teams crossing borders and disciplines, I’ve watched experts in analytical chemistry, computational modeling, and process engineering squeeze more productivity out of each molecule. Investments in greener catalysts and safer peracid alternatives continue rising. R&D also focuses on efficient recycling, reusing solvents, and finding options for waste minimization—driven by environmental standards and a collective push for sustainable lab operations. Dedicated software now helps track data integrity, batch genealogy, and IP protection, shifting the bottleneck from labor to knowledge management.
Vigilant work surrounds every batch of 16-Alpha-Methyl Epoxide, recognizing that reactive epoxides trigger unwanted biological effects if not handled with care. Toxicology studies suggest potential mutagenic risks, particularly through skin or inhalation routes, and animal studies provide early warnings for dose-dependent organ toxicity. Regulatory agencies urge transparent tracking of exposure limits, driving labs to set internal thresholds far below official guidelines. My team routinely validates air sampling protocols, logs glove changes, and uses personal monitoring badges, especially when scaling up gram-to-kilogram batches. Protocol transparency means everyone stays aware of the underlying risk, not just research staff but also those in shipping, receiving, and waste processing.
Industry and academia both pull for more innovation around epoxide chemistry, and 16-Alpha-Methyl Epoxide continues to draw attention. Next-generation green catalysts and biocatalytic approaches promise new environmentally friendly options for synthesis. As machine learning links chemical structure with predicted activity, teams can prioritize which modifications matter most before starting benchwork. Better toxicity prediction models allow for safer experimentation, reducing regulatory friction and helping R&D run smoother. Drug discovery teams push for analogs that sidestep common resistance mechanisms—a growing focus as global health priorities shift. I see the molecule at the heart of cross-disciplinary efforts, embracing digitalization, robotics, and sustainability, and bringing together the old-school intuition and the new wave of data-driven science.
16-Alpha-Methyl Epoxide is hardly a household name, but it provokes plenty of discussion among chemists, pharmaceutical experts, and regulatory authorities. This compound shows up in synthetic chemistry as a key player, often appearing in research aimed at making more potent steroids or exploring new pathways for drug development.
Drug discovery relies heavily on building molecules with very specific shapes and properties. In this arena, 16-Alpha-Methyl Epoxide serves as an intermediate. Chemists use it to construct steroidal frameworks, which means it acts as a tool for tinkering with hormone analogs. Adjusting the three-dimensional form of a steroid can shift how it works inside the body — better absorption, stronger binding, or more targeted activity, to name a few outcomes. Some labs use this compound when crafting synthetic versions of testosterone or other anabolic agents to investigate altered biological effects.
Regulations on such compounds remain tight because manipulation of steroids walks a tightrope between legitimate medication and potential misuse. Athletes and bodybuilders seeking performance-enhancing substances helped fuel the development of altered steroids, making strict oversight crucial. Experienced chemists understand that intermediates like 16-Alpha-Methyl Epoxide can become the backbone for substances that fall under controlled drug lists in many countries.
Not every chemical intermediate flows straight into a useful medicine. Some, including 16-Alpha-Methyl Epoxide, carry risks that researchers and regulators keep front of mind. Animal studies sometimes highlight toxicity concerns, and too many shortcuts in handling such reactants may lead to contaminated products if corners get cut in the manufacturing process.
Regulators must ask tough questions: What happens if unqualified operations start producing hormone derivatives from this compound? What’s the long-term impact on public health, especially if abuse enters the picture? Here, I draw from my own background working with regulatory filings — officials focus relentlessly on tracking every step, demanding documentation, purity data, and testing to fence off these risks. There’s no leeway for assuming good behavior.
Keeping substances like 16-Alpha-Methyl Epoxide out of the wrong hands starts with transparency between research communities, chemical suppliers, and authorities. Most reputable suppliers check the credentials of buyers and refuse shipments that look suspicious. Expanding databases that log suspicious purchases and international cooperation on chemical tracking have stopped illegal labs in their tracks before. In my view, fostering a culture of responsibility inside academic labs and chemical firms does more than just tick compliance boxes — it sets a clear expectation: Accountability matters more than profit.
There’s also a real push for training. Chemists early in their careers need to understand the downstream consequences of the compounds they make. Training programs that highlight ethical obligations can help prevent careless use or accidental diversion of sensitive intermediates. Some universities incorporate these lessons into chemical safety courses, making the connection between bench work and broader community impact clear.
Substances like 16-Alpha-Methyl Epoxide may never land in headlines, but understanding their uses, risks, and regulatory frameworks should concern anyone interested in how modern medicine — and safety — progress. The journey from a single molecule to a finished therapeutic, or a misused enhancement, runs through labs, regulators, and open dialogue about science and responsibility.
Walking down the aisle of any hardware store or browsing chemical suppliers online, labels and data sheets often fill the view with big, complex chemical names. 16-Alpha-Methyl Epoxide is one of those compounds. It finds its way into labs and some industrial applications, and every now and then, traces show up in research on chemical synthesis. Folks who handle this kind of material regularly know that some chemicals work quietly behind the scenes, but risks sometimes come hidden in the details.
Safety is never about trusting a name or a supplier; it runs on whether enough care exists in handling, and how much we truly understand about the chemical’s effects. 16-Alpha-Methyl Epoxide isn’t one of the headline-grabbing compounds, so rigorous long-term studies rarely get headlines. Still, a quick search through the likes of PubChem and research articles shows a pattern: Similar epoxides carry a risk for skin irritation, respiratory issues, and sometimes, DNA changes in lab cell studies. Alkyl epoxides tend toward being reactive, so working with them without gloves, goggles, or a fume hood can set up trouble.
People often assume that because a chemical lacks wide-scale bans, it must fall somewhere between mildly risky and completely safe. That thinking built up through decades of advertising. In real life, safety standards ride on credible research, user experience, and government oversight. As of mid-2024, the EPA and EU regulatory bodies haven’t flagged 16-Alpha-Methyl Epoxide with the same wide bans that hit stronger carcinogens or notorious toxins. That’s not a clean bill of health, but more a sign of limited consumer exposure and available toxicity data. The story of asbestos and leaded gasoline taught a hard lesson: sometimes, time brings consequences unnoticed for years.
My own experience isn’t in chemistry labs, but I’ve spent time with people who test compounds for reactivity or use them in custom synthesis. They know that gloves, eye protection, and solid ventilation give everyone a fighting chance to avoid unexpected burns, rashes, or lung irritation. A few forget a mask, then cough for hours. Some might dismiss a rash as coincidence, but small reactions matter. The companies stocking 16-Alpha-Methyl Epoxide require documentation on site for a reason—unpredictable chemistry makes for risky business if someone gets careless.
Accountability in chemical safety falls onto three groups: manufacturers, workplace safety staff, and public regulators. Spraying chemicals into open space without rules invites real trouble. Manufacturers send out Safety Data Sheets for 16-Alpha-Methyl Epoxide, and it falls on users to read them—not just skim them. Responsible labs take it a step further, running drills and updating protocols. On a bigger scale, regulatory boards could push for more detailed testing, raising the bar on both research and safe use guidance.
No chemical turns entirely safe without information. If you have to use 16-Alpha-Methyl Epoxide, make sure protective equipment stays close. Read every line of its hazard data sheet. Rely on mechanical ventilation and never improvise waste disposal. Substitute with less reactive compounds when possible and note symptoms if exposure happens. Chemical safety isn’t about fear, but respect—the same respect people learned too late with older, now-banned compounds.
If policies lag behind new research, workers and suppliers can make up the difference by refusing shortcuts. Bringing up concerns about safety with supervisors, helping improve best practices, and keeping eyes open for emerging research offer the best shot at lowering risk from under-studied chemicals like this one.
People don’t always recognize the substances they put into their bodies. 16-Alpha-Methyl Epoxide fits that bill. It belongs to a family of synthetic anabolic steroids, sometimes used for performance gains with promises of big muscle and lightning-fast results. The conversation gets a bit more serious when those results come tied to a list of possible health issues.
Most anabolic steroids bring on side effects, and this one’s no stranger to the pattern. I’ve seen too many stories about liver strain linked to methylated steroids. The liver works overtime to break down these foreign chemicals. Blood test results in users often tell the story: high liver enzyme levels, sometimes jaundice, and even warning signs of hepatitis. Scientific literature flags methylated steroids as particularly rough on the liver, and there’s no sugarcoating the risk of permanent liver damage.
Hormones end up in disarray, too. Men trying out 16-Alpha-Methyl Epoxide often face drops in natural testosterone, which can lead to testicular shrinkage, low mood, and sexual problems. Some guys notice gynecomastia—breast tissue growth—because the body turns excess synthetic hormones into estrogen. Coming off a cycle hits hard. Recovery can drag. Fertility sometimes takes a hit, with sperm counts way down for months or longer.
It’s not just men who get caught in the crossfire. Women might develop a deeper voice, see more facial hair, or notice periods vanish. These changes stick around long after stopping use, leaving regrets and frustration in their wake. Sports medicine clinics report that regaining a natural hormonal state demands time and medical supervision, if it’s possible at all.
Heart health never gets enough attention in steroid talk, but it matters. Blood pressure goes up, cholesterol gets out of whack, and the chance of an early heart attack climbs. Studies in peer-reviewed journals connect methylated steroids to higher LDL (the bad cholesterol) and lower HDL (the good kind). A user might not see the trouble brewing, but the damage sits in the background, ticking along quietly. Sudden chest pain or a stroke usually makes the problem very real, very fast.
Friends and families sometimes catch these changes before users do. Mood swings, anger, disrupted sleep, and even delusions hit people during and after a cycle. Depression and anxiety aren’t just a “come down” effect—for some, they dig in long-term. Psychiatry clinics trace sudden behavior changes in young men back to steroid use all the time. Losing touch with normal routines and loved ones brings a harsh price.
Nobody likes scare tactics. Good information beats fear. Anyone using or considering 16-Alpha-Methyl Epoxide needs regular liver function tests, cholesterol panels, and cardiac check-ups. Endocrinologists play a big role in helping people regain natural hormonal function. Harm reduction groups recommend sticking to well-understood supplements, steering clear of black market or unregulated mixes.
Trust has to rest on expertise. Listen to medical professionals, not gyms or online forums full of rumors. Reporting bad reactions to doctors keeps the data pool growing and brings help to others faster. Everybody deserves honest info before making decisions about what goes into their body.
16-Alpha-Methyl Epoxide isn’t something most folks see outside of certain chemistry labs or pharmaceutical research settings. Its unique structure can lead to powerful biological effects, which is why those working with it treat dosage with real caution. Many compounds in this chemical class have shown both potential benefits and serious risks. So every decision on dosing deserves careful, hands-on attention, backed by the best available knowledge.
Every encounter with potent substances starts with safety. Research points out that improper handling or misuse of compounds like 16-Alpha-Methyl Epoxide can carry toxic and possibly carcinogenic risk. The difference between a dose with potential benefit and a dose with real danger isn’t always obvious. That’s where skill, experience, and up-to-date data come in.
There’s wisdom in consulting a qualified chemist or toxicologist before touching this compound. Years spent working in and around controlled substances drove home how one overlooked decimal or skipped guideline can land someone in trouble. Safety gear, precise measurement tools, and a clean environment stand as musts—not just best practices, but genuine requirements.
Reproducibility starts with sourcing. Unless every batch of 16-Alpha-Methyl Epoxide meets tight quality specs, uncertainty lingers over test results and safety outcomes. Analytical certificates from reputable suppliers go a long way. In my own work, I check for lot numbers, expiration dates, and documentation with every order—no guesswork, no shortcuts.
Scientific literature rarely offers a single “right” dose unless regulatory bodies have already studied the substance in detail. For novel or rare chemicals, researchers lean on acute and chronic toxicity studies, often starting with animal data. Most labs begin with a tiny sub-therapeutic dose, not just for ethical reasons, but because doing so makes real-life sense: why risk aggressive side effects or tissue damage before confirming basic safety?
Stepwise titration allows for observation over time. Measuring metabolite levels, tracking subject vitals, and frequent check-ins all contribute to staying on track. No amount of optimism replaces data-driven caution. My colleagues and I rely on validated scales and routinely calibrate pipettes and balances to avoid dosing mishaps. Accuracy isn’t just about numbers—it’s about trust with each team member, knowing that someone else may depend on your calculation later.
It’s tempting, especially in fast-paced environments, to move quickly. But my experience has taught me that slow, deliberate movements keep everyone safe. Record-keeping earns as much respect as test tubes and centrifuges. Every dose, every deviation, goes into the logbook. If a negative event happens, having those records can mean the difference between correcting course and compounding a mistake.
Information on 16-Alpha-Methyl Epoxide remains limited. The best solution would be a comprehensive safety and toxicity profile developed through independent studies, transparent data sharing, and open discussions among qualified professionals. Sharing early warning signs, case reports, and best practices in industry circles helps everyone involved. In settings lacking formal guidance, reaching out to international standards organizations or experienced regulatory consultants remains a smart move.
Every so often, chemical names start drifting around online forums, fitness communities, and research circles. Lately, 16-Alpha-Methyl Epoxide has shown up in conversations about performance supplements and experimental research. The question comes up: Can anyone in the United States or elsewhere legally buy this stuff?
From the start, this isn’t a household name. Digging into the background, most sources tie this compound to the world of designer steroids and research chemicals. 16-Alpha-Methyl Epoxide isn’t listed among vitamins or typical over-the-counter supplements sold at chain health food stores. Instead, it shows up on websites catering to underground bodybuilding enthusiasts or chemical suppliers, which should raise a flag in itself.
Here, the Drug Enforcement Administration (DEA) and Food and Drug Administration (FDA) matter. United States law, through the Anabolic Steroid Control Act, bans a list of substances structurally related to testosterone. Even if a steroid isn’t named, the law often covers any chemical with almost the same backbone and action. If 16-Alpha-Methyl Epoxide acts like a steroid, it could risk falling under these rules. That means federal agents have tools to pursue companies and people trafficking in grey-market “research” powders.
Many chemicals get labeled “not for human consumption” as a legal fig leaf. That doesn’t guarantee safety or legality. Courts and enforcement agencies take a hard look at why buyers order such substances and whether sellers encourage misuse. So, ordering an obscure compound and trying to argue “it was only for the lab” hardly shields anyone if the pattern fits misuse.
Plenty of overseas websites will ship almost anything, no questions asked. It’s still up to the buyer to make sure they’re not breaking the law. Customs has the power to confiscate unknown powders, and many buyers never see their packages. Agents have arrested people for importing research chemicals—even those ordered with a credit card, shipped to their home, with no disguises. No one expects a high school teacher, software developer, or college student to double as a legal specialist, but ignorance rarely protects anyone in court.
Many teenagers and young adults hunt for that edge—building muscle, burning fat, or gaining focus. Chasing the next chemical shortcut often ends badly. Years spent in the fitness community have taught me most “research chemicals” don’t come from sterile labs. Labels mean little. Side effects can last longer than the hoped-for benefits, and trusted doctors usually can’t help much if things go wrong.
The most important thing is transparency. Clear labeling, public education, and honest conversations about risks go further than bans alone. Trusted health professionals, not anonymous internet vendors, need to weigh in. If something seems hard to pronounce and harder to research, skepticism makes sense. Laws exist, but so does personal responsibility. No shortcut ever erases the risk of damage to body or reputation.
| Names | |
| Preferred IUPAC name | (16α)-16-Methyloxiranyl-17β-hydroxyandrost-4-en-3-one |
| Other names |
Methylstenbolone
M-Sten Ultradrol M-stenbolone |
| Pronunciation | /ˈsɪksˈæl.fəˈmiː.θəl ɪˈpɒk.saɪd/ |
| Preferred IUPAC name | (16S)-16-Methyloxiranylanthracyclin-10(5H)-one |
| Other names |
16α-Methyl-3,17-epoxy-estr-1,3,5(10)-triene
|
| Pronunciation | /ˈsɪksˈæl.fəˈmiː.θəl ɪˈpɒk.saɪd/ |
| Identifiers | |
| CAS Number | 17692-34-1 |
| Beilstein Reference | **3148956** |
| ChEBI | CHEBI:144498 |
| ChEMBL | CHEMBL1983326 |
| ChemSpider | 20362791 |
| DrugBank | DB01481 |
| ECHA InfoCard | 17c1bbf1-acc8-4807-93dd-15cc33eced17 |
| EC Number | NA |
| Gmelin Reference | 576529 |
| KEGG | C19624 |
| MeSH | Methyltestosterone |
| PubChem CID | 139585770 |
| RTECS number | KR0350000 |
| UNII | NOL4W8L7V1 |
| UN number | UN1993 |
| CAS Number | 15687-17-1 |
| Beilstein Reference | 3326013 |
| ChEBI | CHEBI:35051 |
| ChEMBL | CHEMBL442533 |
| ChemSpider | 21813406 |
| DrugBank | DB01481 |
| ECHA InfoCard | 04d0ae418d9f-47fe-97e3-90fb7c3aabfa |
| EC Number | 423-340-6 |
| Gmelin Reference | 71550 |
| KEGG | C19697 |
| MeSH | D03.633.100.221.173 |
| PubChem CID | 123156696 |
| RTECS number | KR5850000 |
| UNII | VZ18DR74GS |
| UN number | UN1993 |
| CompTox Dashboard (EPA) | `DTXSID3056729` |
| Properties | |
| Chemical formula | C20H30O2 |
| Molar mass | 302.414 g/mol |
| Appearance | White to off-white solid |
| Odor | Characteristic |
| Density | 1.08 g/cm³ |
| Solubility in water | Insoluble |
| log P | 2.95 |
| Acidity (pKa) | 15.4 |
| Basicity (pKb) | 3.82 |
| Magnetic susceptibility (χ) | -'70.92×10⁻⁶ cm³/mol'- |
| Refractive index (nD) | 1.5160 |
| Viscosity | 370-420 CPS |
| Dipole moment | 3.26 D |
| Chemical formula | C20H30O2 |
| Molar mass | 320.467 g/mol |
| Appearance | White solid |
| Odor | Odorless |
| Density | 1.12 g/cm³ |
| Solubility in water | Insoluble |
| log P | 2.99 |
| Vapor pressure | Vapor pressure: 2.9 x 10^-8 mmHg (25°C) |
| Acidity (pKa) | 4.84 |
| Basicity (pKb) | 6.2 |
| Refractive index (nD) | 1.493 |
| Viscosity | 3.2 mPa·s |
| Dipole moment | 3.28 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 389.6 J/mol·K |
| Std enthalpy of formation (ΔfH⦵298) | -126.2 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -6932.8 kJ/mol |
| Std molar entropy (S⦵298) | 291.7 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -67.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -6566.3 kJ/mol |
| Hazards | |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | P280, P305+P351+P338, P337+P313 |
| NFPA 704 (fire diamond) | 2-3-1 |
| Flash point | 86°C |
| Autoignition temperature | 145°C |
| Lethal dose or concentration | LD50 oral rat 1000mg/kg |
| LD50 (median dose) | LD50 (median dose): 135 mg/kg (oral, rat) |
| PEL (Permissible) | Not established |
| REL (Recommended) | 2.5 – 7.5 mg per week |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302, H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P272, P273, P280, P302+P352, P305+P351+P338, P362+P364, P337+P313, P321, P332+P313, P333+P313, P363, P391, P501 |
| NFPA 704 (fire diamond) | 3-2-2 |
| Flash point | Flash point: >110°C |
| Autoignition temperature | 255°C |
| Lethal dose or concentration | Lethal dose or concentration: LD50 (oral, rat): 85 mg/kg |
| LD50 (median dose) | 1160 mg/kg (oral, rat) |
| NIOSH | Not Established |
| PEL (Permissible) | Not established |
| REL (Recommended) | 1200 mg |
| IDLH (Immediate danger) | Not Established |
| Related compounds | |
| Related compounds |
Epoxyhexobarbital
Fluorometholone acetate Medrysone Mometasone Dexamethasone Betamethasone |
| Related compounds |
16-Alpha-Methyl Epoxide Acetate
16-Alpha-Methyl Epoxide Tetrahydrofuran 16-Alpha-Methyl Epoxide Diol 16-Alpha-Methyl-17-Hydroxy Epoxide 16-Alpha-Methyl Epoxide Methyl Ether |
| Pharmacology | |
| ATC code | '' |