Product Name: 17-Methyltestosterone
Chemical Name: 17β-Hydroxy-17-methylandrost-4-en-3-one
CAS Number: 58-18-4
Molecular Formula: C20H30O2
Recommended Uses: Veterinary pharmaceutical, aquaculture feed additive, research chemical
Manufacturer Contact: Available from supplier or production source; maintain updated contact for emergencies.
Emergency Contact: Refer to national poison control and medical response teams.
GHS Classification: Reproductive toxicity, specific target organ toxicity, suspected carcinogen
Signal Word: Danger
Hazard Statements: May damage fertility, risk of endocrine disruption, harmful if swallowed, may cause respiratory irritation
Pictograms: Health hazard, exclamation mark
Precautionary Statements: Avoid contact with skin, eyes, and clothing; do not breathe dust; use personal protective equipment; keep out of reach of children.
Chemical: 17-Methyltestosterone
Concentration: Technical grade, minimum 97% purity
Impurities: Residual solvents, trace precursors depending on synthesis method, any specific stabilizers noted by supplier
Additives: None typically present for laboratory grade material.
Inhalation: Move person to fresh air; seek medical attention for persistent symptoms such as coughing, dizziness, or throat irritation.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water; do not reuse contaminated clothing until cleaned.
Eye Contact: Immediately rinse eyes under running water for at least fifteen minutes, including under eyelids; seek medical advice.
Ingestion: Rinse mouth with water; do not induce vomiting; seek prompt medical care.
General care: Watch for delayed symptoms, especially hormonal disturbances; report full exposure details to healthcare professionals.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Specific Hazards: Material may emit toxic fumes including carbon monoxide, carbon dioxide during combustion
Protective Equipment: Chemical-resistant suit, self-contained breathing apparatus
Additional Instructions: Move containers from fire if safe; use water spray to cool fire-exposed surfaces; prevent runoff from entering drains or watercourses.
Personal Precautions: Evacuate unprotected personnel, ventilate area, limit access; use suitable gloves, goggles, and respirator.
Environmental Precautions: Prevent spillage from entering soil, drains, and waterways; collect powder or crystals gently using avoid dust generation.
Clean-Up Methods: Use damp absorbent material for collection; store collected spill in sealed, labelled container for disposal following local guidelines.
Reporting: Notify emergency services in case of environmental contamination or large-scale release.
Handling: Work in well-ventilated or fume hood environments; avoid contact with incompatible chemicals and oxidizers; avoid formation of dust and aerosols during transfer or preparation; handle with non-permeable gloves and laboratory safety eyewear.
Storage: Keep product in tightly sealed original containers away from light, moisture, heat, and sources of ignition; recommended temperature between 2–8°C; store separately from food, beverages, and incompatible substances.
Incompatible Materials: Strong oxidizers, acids, bases, reducing agents.
Exposure Limits: Occupational exposure limit values not formally established; minimize exposure based on best laboratory safety practices
Engineering Controls: Use local exhaust ventilation or fume hood; avoid open handling in confined spaces.
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat, optionally NIOSH-approved respirator if dust or aerosols may form.
Hygiene Measures: Wash hands and face after use, avoid eating or drinking in work area, keep contaminated equipment isolated.
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: Not applicable
Melting Point: 162–166°C
Boiling Point: Decomposes before boiling
Flash Point: Not available
Solubility: Very slightly soluble in water; soluble in ethanol, chloroform, ether, vegetable oils
Partition Coefficient (log Kow): High (value around 3.5–4.0)
Vapor Pressure: Negligible at room temperature
Relative Density: Approx. 1.1–1.2 g/cm³
Stability: Stable under recommended storage conditions
Chemical Stability: Stable under normal temperatures and pressures away from direct sunlight, moisture, and incompatible materials
Hazardous Decomposition: May release carbon monoxide, carbon dioxide, other toxic gases under fire or decomposition conditions
Incompatibility: Strong oxidizers, acids, alkalis
Polymerization: No hazardous polymerization expected
Conditions to Avoid: Elevated temperatures, exposure to sunlight, excess humidity, strong oxidizing environments
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Effects: Irritation to eyes, skin, mucous membranes; headache, nausea, dizziness possible for poorly ventilated environments
Chronic Effects: Endocrine disruption, potential reproductive effects, risk of masculinization or feminization, liver toxicity at high doses
Carcinogenicity: Possible human carcinogen based on animal studies and analog drugs
Sensitization: Unlikely with brief exposures, long-term effects not fully characterized
LD50 (mean lethal dose): Exact values not well defined, toxicity noted at low mg/kg in repeat-dose studies on animals.
Symptoms of Overexposure: Hormonal imbalances, mood changes, menstrual irregularities, skin changes
Aquatic Toxicity: Harmful to aquatic organisms; causes endocrine disruption in fish and invertebrates at trace concentrations
Persistence and Degradability: Only partially biodegradable in typical environmental conditions; significant persistence in sediment and water
Bioaccumulation: High potential for bioaccumulation due to hydrophobic properties; persistent in higher trophic levels
Mobility in Soil: Low, binds strongly to sediment and organic matter
Other Adverse Effects: Hormonal effects on aquatic ecosystems; reproductive disruption in exposed organisms has been documented
Waste Treatment Methods: Dispose of waste material as hazardous chemical waste in accordance with local and national regulations
Container Disposal: Rinse containers with appropriate solvent, then send for professional chemical waste destruction
Precautions: Avoid discharge into drains, waterways, or open environment; tightly seal waste containers
Other Info: Keep detailed disposal records for audit and compliance
UN Number: Consult with authority; not usually classified under UN Dangerous Goods, but subject to regulation as a pharmaceutical chemical
Transport Hazard Class: Not generally classified as hazardous for transport, but handle as a controlled substance
Packing Group: None assigned, use secure, leak-proof packaging
Marine Pollutant: Yes, risk for aquatic systems
Labelling: Clearly mark as “Pharmaceutical Chemical” and “Endocrine-Active Substance”; maintain documentation during transportation
Special Precautions: Separate from foodstuffs, animal feeds during all transportation stages
Regulatory Status: Controlled substance in many jurisdictions, subject to prescription or authorization for use
OSHA Status: Not specifically regulated, but general laboratory and carcinogen safety rules apply
EPA:** Registered as aquatic toxic chemical; release limits established for certain locations
WHMIS (Canada): Classified as toxic, reproductive health hazard
REACH (EU): Subject to registration and authorization for industrial and research use
State Laws: Subject to additional licensing and handling restrictions depending on country and application
Other Regulations: Mandatory reporting for significant spills or environmental releases – contact local authorities for guidance
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