Betamethasone Dipropionate came onto the pharmaceutical scene thanks to decades of research into corticosteroids. Scientists spent the middle of the 20th century racing each other to find ways to harness the immune-suppressing power of steroids while dialing back unwanted side effects. Early glucocorticoids helped a lot of people, but folks on the front lines kept reporting bad skin thinning, irritation, and more. Chemists made careful tweaks to molecular structures, searching for that line where benefits remain strong but drawbacks don’t knock people off their feet. Betamethasone, with its double esterification, grew from this dogged research. It raised the bar for topical steroids, giving patients and doctors a tool that meant relief came with less worry about the fallout. Over the years, regulatory agencies, dermatologists, and pharmacists helped refine its use, building a mountain of clinical evidence that shows why it continues to anchor eczema and psoriasis treatment guidelines.
Betamethasone Dipropionate ranks near the top when dermatologists look for something to tame angry, inflamed skin. Its reputation rests on studies that demonstrate prompt control over swelling, redness, and itch. The topical formulation usually lands in ointment, cream, or lotion form. Drug stores and hospital pharmacies treat it almost like an old friend—reliable, powerful, but not one you let run wild without checking on things like skin thickness, patient history, or age. Branded and generic names dot pharmacy shelves worldwide, reflecting its wide acceptance. Insurance data and prescription monitoring show it as a mainstay, used over and over by a diverse set of patients who need something stronger than over-the-counter options but aren’t served by oral steroids.
This compound shows up as a white crystalline powder. The structure, a glucocorticoid backbone with dipropionate esters, matters a lot for what happens on the skin. The esters slow down how fast the steroid leaves the formulation, so anti-inflammatory action stays local and does its job. It is practically insoluble in water, but solvents like ethanol or acetone dissolve it pretty well, which shapes its inclusion in creams and ointments. Heat and light stability, along with low volatility, give manufacturers and pharmacists a reasonable margin of safety for typical storage conditions. Laboratories catalog its details: molecular formula C28H37FO7, molecular weight 504.59 g/mol. Melting point hovers around 176-180°C. Chemical suppliers and regulatory filings all agree these features influence every step from raw material handling to compounding.
Pharmacists, regulatory folks, and anyone who wears a quality assurance badge often turn their focus toward technical standards. USP and other pharmacopeias demand tight requirements on content uniformity, related substances, and microbial testing. Labels must show the precise concentration—typically 0.05% in creams and ointments. Expiry dating follows well-documented stability studies, and correct storage details prevent the drug from losing its potency. Package inserts flag the risks: systemic absorption can occur, especially in children or under occlusion. Warning statements about not using the product for prolonged periods or on broken skin run in bold print. Pharmacovigilance programs require manufacturers to monitor and report side effects, particularly given the increase in topical steroid misuse.
Manufacturing Betamethasone Dipropionate begins with sourcing quality starting materials. The synthetic process needs high purity betamethasone and propionic anhydride. In practice, these react in the presence of solvents and catalysts, with strict control over temperature and pH. The reaction gets monitored step by step, with chromatography checking for byproducts. Purification follows, often involving recrystallization, and the resulting powder goes through rigorous testing. Formulation into a cream or ointment takes place in clean rooms where temperature, humidity, and microbial conditions get tracked every hour. Skilled workers blend the active ingredient with excipients like white soft paraffin, propylene glycol, or emulsifiers, ensuring batch-to-batch consistency. Each batch faces checks for potency, pH, preservative activity, texture, and microbial contamination.
Scientists look at Betamethasone Dipropionate and see possibilities beyond what sits in the ointment jar. Modifying its ester groups could tweak how fast it moves into skin or gets metabolized. Some researchers, aiming to make it safer for long-term use, change the propionate groups for different esters, seeking a combination that delivers local power without seeping into the bloodstream. In the lab, controlled hydrolysis splits the dipropionate off, testing what happens with the unmodified steroid. Various analytical methods—NMR, mass spectrometry, HPLC—confirm structural changes and help regulators ensure nothing unexpected turns up in the process. New salt forms and carrier vehicles entice R&D labs looking for better skin penetration or less irritation.
Betamethasone Dipropionate goes by many names, making things a headache for folks tracking adverse reactions or reading old studies. Trade names dot the map: Diprosone, Diprolene, Celestoderm-V, among others. It shows up in combination products with antifungals or antibiotics, meant to knock out inflammation and infection in a single swipe. Across regulatory languages, synonyms like BD, betamethasone 17,21-dipropionate, and more appear. Pharmacists and healthcare workers need clear cross-referencing, since switching brands or generics shouldn’t expose patients to unnecessary risk.
Healthcare providers carry the responsibility to monitor how Betamethasone Dipropionate gets used. The medical literature and adverse event databases highlight two big issues: local skin damage and systemic steroid effects. Skin thinning, stretch marks, and easy bruising appear with repeated overuse. Children run higher risks, since their skin absorbs more drug relative to their size. Quality control during manufacture, as well as pharmacist counseling when dispensing, builds a layer of protection. Regulatory authorities like the FDA, EMA, and others mandate Good Manufacturing Practice (GMP) compliance. Safety data sheets in factories warn about dust inhalation and skin contact, since direct handling at high concentrations poses hazards that daily end users don’t see. Education programs for doctors and patients alike try to slow down inappropriate use.
The list of problems Betamethasone Dipropionate addresses starts with moderate to severe inflammatory skin diseases. Psoriasis, atopic dermatitis, contact dermatitis, and lichen planus belong here. Burns units, surgical clinics, and pediatricians turn to it when gentler creams don’t calm things down. In low-income clinics and refugee health posts, it often serves as the last best hope for patients with limited options. There’s more, though: some rare autoimmune blistering diseases respond only to high-potency topicals, and this compound delivers. Its off-label use stretches into post-radiation skin care, insect bite management, and even some pain syndromes affecting nerves near the skin’s surface. Still, the risk-benefit gears up for rebalancing every time someone writes a prescription, because chronic, unsupervised use stacks up risks.
Pharmaceutical companies pour money into R&D aimed at staying ahead of generic erosion and finding new uses. Nanoparticle delivery systems, emulsion gels, and foam formulations catch the eye of anyone trying to outmaneuver steroid-phobia in the patient population. Research teams also trawl through patient databases, looking for signals that point to overdosing or misuse, and then use that data to develop educational campaigns or prescription monitoring tools. Collaboration with academic immunologists, dermatologists, and pharmacologists ties real-world patient experience to the development pipeline. Just in the past decade, papers have shown modest progress in reducing side effects through smarter vehicles and controlled-release formulations.
Toxicological data support the need for caution. Animal studies confirm that, like other potent steroids, Betamethasone Dipropionate at high dosages or under occlusion can suppress the hypothalamic-pituitary-adrenal (HPA) axis, raising concerns about long-term use in children and the elderly. Reports link prolonged application with local immune suppression, delayed wound healing, and secondary infections. A handful of cases in the literature describe glaucoma and cataract with use too close to the eyes. Toxicity monitoring moves beyond the initial approval phase, relying on patient registries, adverse event reporting, and post-marketing surveillance that bring a steady drip of safety updates. Clinics respond with tighter controls, visual monitoring of at-risk skin, and regular follow-ups, especially with patients dealing with chronic dermatologic illness.
The future for Betamethasone Dipropionate isn’t just about tweaking molecules. There’s growing demand for “steroid-sparing” regimens, with pressure coming from both patient advocates and regulatory agencies. Personalized medicine, using pharmacogenomics and skin microbiome research, promises better targeting of treatment for those who will benefit most. Companies look toward partnership with digital health platforms to track how and when patients apply their medication, giving clinicians new tools to reinforce correct habits. As patents expire in different markets, manufacturers cut costs and expand access through generic production, raising hopes for underserved populations who didn’t always see these drugs before. The risk management space keeps evolving; some platforms use AI to flag patients at risk of overuse or rare complications, aiming to make this old molecule work smarter, not just harder, and to keep it both useful and safe for decades to come.
Most people notice a red, itchy patch and figure a little over-the-counter cream will clear it up. Skin problems can turn stubborn quickly. After years of working in healthcare and seeing persistent rashes — from eczema that just won’t quit, to angry, inflamed patches from allergies — I’ve watched people struggle to get relief. Betamethasone dipropionate entered the scene years ago for a reason. As a strong corticosteroid, it packs a punch against skin inflammation. Dermatologists still trust it for hard-to-treat skin problems.
Betamethasone dipropionate cream or ointment isn’t for your average bug bite. The FDA gave a green light for this medicine to treat chronic skin conditions like psoriasis, eczema, and stubborn dermatitis. These are the kinds of problems that keep people scratching at night or hiding their arms at work. I’ve seen kids bullied at school for noticeable eczema, and adults shy away from swimming pools to keep red, flaky skin out of view. When steroid creams like hydrocortisone get you nowhere, doctors reach for the stronger stuff.
The science confirms why it works. Betamethasone dipropionate tames overactive immune responses in the skin, bringing down swelling, redness, and the urge to scratch. United States prescribing references rank it as a “high-potency” topical steroid. For the average person, stronger usually means more powerful results, but also more risks.
That extra punch doesn’t come without a warning. Long-term or careless use can thin the skin, trigger strange color changes, or even let infections set in. Too much, over time, sometimes seeps through the skin and messes with hormones. In the clinic, I’ve talked to more than one parent startled to see stretch marks on a child’s arms from steroids. Fact is, no one should treat these creams like moisturizers. The data shows risk grows when people use it on the face or for long stretches without a doctor’s review.
Insurance companies and pharmacies have seen costs creep up for specialty creams, yet not everyone needs the strongest formula. My experience says education works better than blanket restrictions. Teaching patients how — and how long — to use the medication keeps it effective and limits harm. Doctors warn people not to wrap treated skin with cling film or heavy bandages, which pulls more medicine in and raises risk.
Many patients ask about natural options or feel anxious about using a strong steroid for their skin. Doctors now try to combine quick steroid bursts with gentle, long-term moisturizers and non-steroid meds. Clear instructions matter: apply only to the inflamed patch, don’t double dose, check back in after a couple of weeks.
Chronic skin conditions carry a heavy burden, both emotional and physical. I’ve seen firsthand how a safe, well-monitored plan using betamethasone dipropionate can break the cycle of suffering. More research goes into alternatives every year, but for severe flare-ups, few treatments work as fast and reliably. The key lies in using the medicine wisely, with guidance. Education and access to regular medical advice matter as much as the cream itself.
A lot of folks open a tube of prescription cream, stare at the label, and then hope for the best. I’ve used a few prescription creams myself, including Betamethasone. After talking with pharmacists and dealing with stubborn rashes, one thing stands out: following common-sense steps keeps skin and health in good shape with strong medicines like this.
Betamethasone dipropionate doesn’t compare to drugstore lotions. This cream works for everything from eczema to psoriasis. It calms inflammation fast, but it doesn’t mean slathering extra will heal anything quicker. Doctors prescribe this because its power can stop redness, itching, and swelling when weaker creams haven’t helped.
Put this cream on clean, dry skin. I learned early on that hurried or sloppy washing—especially for hands and arms—can trap dirt under the medicine and lead to redness or burning. Use mild soap, rinse well, and pat the skin dry with a clean towel. Scrubbing or using hot water can make things sting once the cream goes on, so stick with lukewarm water and gentle pressure.
Pharmacists talk about “the fingertip unit”—the amount that covers from the tip of an adult finger to the first crease. This covers an area about the size of two adult palms. Most people end up using way more than needed. One fingertip unit works for a spot, not the whole arm or leg. I once coated a large eczema patch and felt the burn—so following this measurement makes a difference.
Apply a thin layer to the affected skin. No need to rub hard or massage deeply. Gentle, even strokes get the job done without damaging skin. Cover only the rashes, not healthy skin around the area. If hands need treatment, don’t wash them after applying. If not, wash hands thoroughly, since steroid creams absorb fast and shouldn’t go near the eyes, mouth, or sensitive areas.
Doctors usually say to use the cream once or twice daily. Doubling up doesn’t speed healing and only raises the risk of side effects like thinning skin or acne. Set a reminder if you forget midday doses—consistency builds better results with most skin problems.
Steroid creams like this shouldn’t become a daily routine past a few weeks unless a doctor clearly says so. Going on for months can thin skin or trigger new breakouts. If rashes return right after stopping, check back with your doctor—sometimes, another product or approach works better long-term.
Store the tube at room temperature. Keep it capped—open tubes can dry out or get contaminated. Don’t share with family or friends even if those rashes look the same—skin conditions come from many causes and one person’s solution can make someone else worse off. If itching or redness spreads, call your provider early rather than hoping things will settle overnight.
Avoid triggers like harsh soaps, perfumed products, and scratching. Use unscented moisturizers and wear breathable clothing so rashes heal faster. Health insurance and pharmacist websites often have guides—these can break down advice by age group or condition, making things clearer if you’re new to using prescription creams.
A lot of folks reach for Betamethasone Dipropionate cream when their skin flares up. The relief feels immediate: it cuts the itch, tames angry rashes, and soothes stubborn eczema. Fast results make it tempting to apply any time red patches return. Trouble is, this steroid cream asks for some real caution, and a plain-talk look at side effects can help people stay safe.
Years back, my dermatologist handed me a small tube for stubborn patches on my elbows. After a few weeks, my eczema faded, but the skin in those spots seemed thinner and almost see-through. I learned later that long-term use, especially on delicate areas, risks thinning out skin—doctors call this “skin atrophy.” I remember a neighbor who tried the same for psoriasis on his face; he ended up with broken capillaries around his nose. These aren’t rare stories in the waiting room.
Doctors warn that daily use can dry out skin, trigger stinging, and leave a burning feeling. Folks often report lighter skin patches, bruising, and stretch marks where they apply it most. Hair growth speeds up on treated spots, and you might notice acne or red bumps. For anyone who’s ever felt embarrassed by a shiny, thin patch of skin after treating a rash, that’s no exaggeration.
Most cream users never imagine steroid medicine reaching the bloodstream, but it can happen, mostly after months or over large patches. Younger children and older adults face more risk. Researchers have reported symptoms like weight gain, swollen faces, mood swings, and even blood sugar spikes. In worst cases, the body slows its own hormone production, leading to problems you definitely don’t want to ignore—fatigue, muscle weakness, and slow growth for kids.
Pharmacies fill countless steroid ointment prescriptions without much explanation. People use it on the face, underarms, or groin, where the skin absorbs medicine faster. Too many skip checking with their doctor if symptoms fade, then return. Over-the-counter versions seem easy, but that easy fix hides trouble if used week after week.
Ask your doctor each time you refill—especially before using on your face or for kids. Stop as soon as the rash dies down, not after the itching’s been gone for a while. Switch to a plain moisturizer for maintenance, not more steroid cream. If you spot skin that feels paper-thin or bruises quickly, head back to your clinic. Doctors can recommend milder steroids or different treatment plans for chronic conditions.
The American Academy of Dermatology points out that using strong steroid creams comes with trade-offs. A British study saw visible skin changes in 20% of people using Betamethasone for just two weeks. Experts have shown that children are more likely to absorb enough through their skin to cause hormonal shifts. Pharmaceutical sheets urge users to avoid broken skin and never cover large areas without medical instruction.
Managing flare-ups matters, but respecting side effects sets the stage for real healing. Only let a licensed professional call the shots about where, when, and how much to use. Keeping steroids as a backup, not the main course, helps skin recover over the long haul.
Betamethasone dipropionate cream often shows up in medicine cabinets after a trip to the dermatologist for stubborn rashes or flare-ups. Classified as a potent corticosteroid, it’s no over-the-counter moisturizer. It was designed to calm inflammation, crush redness, and bring relief from itchy, scaling skin conditions like psoriasis and eczema. It beats the weaker hydrocortisone products many people know from drugstores. That strength brings results – for better or worse.
The skin on the face is thinner and more reactive than on most other body parts. Sensitive regions like eyelids, around the mouth, and under the nose can absorb medication faster and in greater amounts. I’ve seen friends reach for betamethasone after a nasty flare-up, hoping for fast relief. The redness might fade at first, but sometimes the rebound is worse. Steroid creams, especially the potent ones, can cause thinning of the skin, enlarged capillaries, and a telltale shine after a while. Stories of patchy discoloration or steroid-induced acne aren’t rare either.
Areas like the groin, armpits, and behind the knees feel more tender because the skin is softer and stays moist. Betamethasone, used carelessly on these spots, can quickly bring on side effects. I’ve listened to patients describe a different sting and noticed small tears or stretch marks forming after repeated use. The risk of systemic side effects – meaning the medicine gets absorbed and starts acting in the whole body, not just on the rash – jumps in these moist folds.
Most dermatologists, including the ones I trust and have worked with, hesitate before giving out prescription-strength steroids for the face or sensitive areas. They might direct patients toward a much milder steroid, sometimes not even a steroid at all. Medical guidelines back this caution up. The American Academy of Dermatology points out the long-term dangers from potent steroids on fragile skin: thinning, bruising, and permanent changes.
A friend of mine learned the hard way after using betamethasone on her eyelids for a week without a doctor’s advice. The swelling shrank, but thin crepey skin stuck around, and getting that back to normal was slow and difficult. For anyone thinking about putting this cream on a rash or redness in a sensitive area, a little patience to see a health professional or at least to double-check your plan pays off. It’s tough to undo damage from overuse.
Doctors often reach for gentler, short-term steroid use, paired with moisturizers or a non-steroid treatment like calcineurin inhibitors for delicate spots. Regular follow-up matters to catch side effects early. For people fighting skin trouble who can’t see a specialist right away, sticking to over-the-counter hydrocortisone for the face (and even then, only for a few days) usually brings less risk.
It’s tempting to look for fast fixes, especially when a rash or breakout pops up. Betamethasone dipropionate has its place in medicine, but not every patch of red deserves such strong firepower – especially across the face or in body folds where skin is extra sensitive. Guidance from a competent professional plays a crucial role in staying safe with high-powered steroid creams and keeping skin healthy long-term.
Pregnancy and breastfeeding turn even simple choices into big decisions. I still remember the first time my partner looked up a topical cream’s ingredients during pregnancy—suddenly, her daily routine turned into a research project. If you’ve been prescribed betamethasone dipropionate, you probably want clear facts, not medical jargon. This is a corticosteroid cream or ointment, used to calm down inflammation from eczema or psoriasis. Many people use it for rashes and itchy skin, trusting it to bring relief. But using anything on your skin during pregnancy or nursing deserves a deeper look, especially when it’s a medicine that can seep in below the surface.
Corticosteroids like betamethasone do reach beyond the skin. Studies with pregnant animals showed that high doses of strong steroids can affect the baby’s growth and cause birth defects. Human studies haven’t shown clear problems from topical use. Still, doctors tend to stick with the basics: fewer risks, the better. Some research suggests a slightly higher risk of low birth weight if large amounts of potent corticosteroids are used over big patches of skin. The American College of Obstetricians and Gynecologists recommends using the weakest steroid possible, in the smallest amount, for the shortest time. Topical use on small, limited areas stays the general advice.
As for nursing, most topical steroids pass into breast milk at extremely low levels. There isn’t much strong evidence showing harm to nursing babies if mothers use betamethasone sparingly and wipe off any cream before feeding. According to LactMed, which compiles data on medicines in breastfeeding, care comes down to timing and thoroughness. Don’t apply the cream directly on or around nipples. If you use it on hands or arms, wash thoroughly before handling your baby or expressing milk. Simple steps make a real difference — my family’s pediatrician always said, “Medicines and babies don’t need to share skin real estate.”
Painful, inflamed skin shouldn’t go untreated. Scratching nonstop during pregnancy or breastfeeding affects sleep, mood, even feeding the baby. But this isn’t the moment to grab prescription ointments without talking to your provider. If a doctor thinks you absolutely need a steroid cream, ask about weaker alternatives or gentle non-steroid options like moisturizers with colloidal oatmeal or ceramides. For many mild cases, these can help avoid any uncertainty. If patchy eczema keeps you up at night, treating it properly supports your own well-being too — and healthy parents take better care of their kids.
Here’s the bottom line: check with your healthcare provider before using betamethasone during pregnancy or nursing. Ask how to apply it in the safest way. Keep doses small, apply to only the affected areas, and avoid broken skin. If you notice anything strange with your own health or your baby’s, follow up with your doctor right away. Write down any instructions and review safe use each time you get a new prescription. Careful, practical steps help ease anxiety and keep both you and your baby safe.
Navigating pregnancy and breastfeeding often means hearing a lot of advice—some helpful, and some just confusing. Talk with a pharmacist or dermatologist if you feel lost in the details. Reliable medical resources and real-life experiences from other parents offer practical knowledge beyond technical leaflets. Every person’s situation looks a little different, so starting the conversation can often lead to solutions you never thought of on your own.
| Names | |
| Preferred IUPAC name | (11β,16β)-9-fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate |
| Other names |
Diprolene
Betaderm Celestone Dipropionate Diprosone Maxivate |
| Pronunciation | /ˌbiː.təˌmiː.θəˈsoʊn daɪˌprɑː.piˈəʊ.neɪt/ |
| Preferred IUPAC name | (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropanoate |
| Other names |
Dipropiona-Beta
Diprosone Bentelan Celestone Dipropionate Diproderm Betnovate DP Propaderm |
| Pronunciation | /ˌbiː.təˌmiː.θəˈsoʊn daɪˌprɑː.pɪˈoʊ.neɪt/ |
| Identifiers | |
| CAS Number | 5593-20-4 |
| Beilstein Reference | 1822634 |
| ChEBI | CHEBI:3078 |
| ChEMBL | CHEMBL1200374 |
| ChemSpider | 15749 |
| DrugBank | DB00443 |
| ECHA InfoCard | 100.047.732 |
| EC Number | 206-993-8 |
| Gmelin Reference | 512426 |
| KEGG | C07292 |
| MeSH | D002041 |
| PubChem CID | 231758 |
| RTECS number | VM7518000 |
| UNII | 8VZV102JFY |
| UN number | UN number not assigned |
| CompTox Dashboard (EPA) | DTXSID6020162 |
| CAS Number | 5593-20-4 |
| Beilstein Reference | 1821049 |
| ChEBI | CHEBI:3078 |
| ChEMBL | CHEMBL1203 |
| ChemSpider | 81906 |
| DrugBank | DB00443 |
| ECHA InfoCard | 100.036.998 |
| EC Number | 206-293-2 |
| Gmelin Reference | 550505 |
| KEGG | C07291 |
| MeSH | D002034 |
| PubChem CID | 230435 |
| RTECS number | VM3150000 |
| UNII | 13T2N7S6A8 |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID8022355 |
| Properties | |
| Chemical formula | C28H37FO7 |
| Molar mass | 504.6 g/mol |
| Appearance | White to almost white, crystalline powder |
| Odor | Odorless |
| Density | 1.13 g/cm3 |
| Solubility in water | Practically insoluble in water |
| log P | 3.7 |
| Vapor pressure | Negligible |
| Acidity (pKa) | 12.53 |
| Basicity (pKb) | 12.38 |
| Magnetic susceptibility (χ) | -8.6E-6 cm³/mol |
| Refractive index (nD) | 1.69 |
| Viscosity | Viscous |
| Dipole moment | 1.73 D |
| Chemical formula | C28H37FO7 |
| Molar mass | 504.605 g/mol |
| Appearance | White to almost white, crystalline powder |
| Odor | Odorless |
| Density | 1.14 g/cm3 |
| Solubility in water | Practically insoluble in water |
| log P | 2.8 |
| Acidity (pKa) | 12.53 |
| Basicity (pKb) | 12.62 |
| Magnetic susceptibility (χ) | -0.000000915 |
| Refractive index (nD) | 1.58 |
| Viscosity | Viscous liquid |
| Dipole moment | 2.33 D |
| Pharmacology | |
| ATC code | D07AC01 |
| ATC code | D07AC01 |
| Hazards | |
| Main hazards | May be harmful if swallowed, inhaled, or absorbed through skin. Causes eye, skin, and respiratory tract irritation. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | PPPP-SMPC-097 |
| Signal word | Warning |
| Hazard statements | Hazard statements: No known significant effects or critical hazards. |
| Precautionary statements | Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin. Use only as directed by your physician. Discontinue use if irritation or sensitivity occurs. |
| Flash point | Flash point: 9°C |
| Lethal dose or concentration | Lethal dose or concentration: LD50 (oral, rat): >3000 mg/kg |
| NIOSH | NQ6S539I5K |
| PEL (Permissible) | Not established |
| REL (Recommended) | 50 micrograms/gram |
| IDLH (Immediate danger) | Not established |
| Main hazards | May cause skin irritation; harmful if swallowed or absorbed through skin; may cause allergic reactions; avoid contact with eyes and mucous membranes. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | CE/N, GSL, S1A |
| Signal word | Warning |
| Hazard statements | Hazard statements": "May cause an allergic skin reaction. Causes serious eye irritation. May cause respiratory irritation. |
| Precautionary statements | Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin. If irritation develops, discontinue use and consult a physician. Use only as directed by your healthcare provider. |
| Flash point | > 218.7 °C |
| Lethal dose or concentration | LD50 (oral, rat): >3000 mg/kg |
| LD50 (median dose) | Mouse oral LD50: >3,000 mg/kg |
| NIOSH | QN6476000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 0.05% |
| IDLH (Immediate danger) | Not established |
| Related compounds | |
| Related compounds |
Betamethasone
Betamethasone valerate Betamethasone sodium phosphate Betamethasone acetate Betamethasone benzoate Betamethasone 17-valerate Dexamethasone Hydrocortisone Clobetasol propionate |
| Related compounds |
Betamethasone
Betamethasone valerate Betamethasone sodium phosphate Betamethasone acetate Betamethasone benzoate Dexamethasone Clobetasol propionate Hydrocortisone Prednisolone Triamcinolone acetonide |
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