Budesonide first rose out of the growing need for effective anti-inflammatory treatments during the 1970s. Researchers were hunting for better asthma management options with fewer side effects than the systemic corticosteroids of that era. By the early 1980s, budesonide found its footing as an inhaled corticosteroid after breakthroughs in understanding targeted lung delivery. Its development mirrored a broader shift in respiratory care: focus sharpened on minimizing long-term harm while controlling symptoms. Decades later, budesonide had become a cornerstone of chronic respiratory disease treatment, helping asthma patients live with fewer hospital visits and more reliable symptom control. You can see the fingerprints of scientific collaboration all over its progress, bridging pharmacology, clinical research, and drug delivery innovation.
Today, pharmacies stock budesonide under several forms such as inhalers, nebulizer suspensions, nasal sprays, and oral capsules. Take Pulmicort or Entocort EC—these products target asthma, allergic rhinitis, and even Crohn’s disease. They reflect how modern medicine bends a single molecule toward different challenges, all through a focus on localized action rather than whole-body exposure. Health professionals value the flexibility these forms bring. Managing a flare-up of Crohn’s disease in the gut requires a different delivery method compared to a sudden asthma attack. People using budesonide don’t just get a one-size-fits-all fix, but a practical tool matched to what their body demands.
Structurally, budesonide falls under the corticosteroid family. Its chemical formula—C25H34O6—reveals a complex mesh of carbon rings and oxygen groups. At room temperature, it’s a white to off-white powder, practically insoluble in water, which nudges drug developers toward suspension or inhalation delivery pathways. Budesonide’s melting point usually hovers around 224°C, which gives an idea of its stability during storage and production. The crystalline nature impacts how the body absorbs and metabolizes the drug, where its high lipophilicity enables it to stick around in the tissues where it does the most good. Pharmacokinetics matter here: after inhalation, only about 39% of a standard dose actually enters systemic circulation, sparing patients from many steroid side effects.
Each country’s drug authorities demand strict labeling for every unit of budesonide sold. Dosage strength, administration route, storage directions, and expiry period appear in detail, alongside critical safety warnings. In outpatient clinics, both adult and pediatric doses are staggered based on disease severity. Inhalers typically carry 100 to 400 micrograms per actuation, and suspensions hover in the range of 0.25 to 0.5 mg per vial. Every label spotlights contraindications like hypersensitivity or certain infections, along with side effects—voice changes, sore throat, and potential immune suppression top the list. Packages usually call for storage below 30°C, away from light and moisture, underlining how chemical stability can make or break treatment outcomes.
The journey from raw chemical precursors to clinical-grade budesonide involves several steps. Chemists often start with an existing corticosteroid skeleton, then introduce functional groups stepwise: oxidizing, reducing, and protecting regions as needed. Modern synthesis leans on reliable yields and high purity, which boils down to careful control over every phase—especially during crystallization. The resulting active compound undergoes rigorous quality control before it’s ever suspended or dissolved in a final product. Once formulated, it passes through sterile filtration and precise filling into inhalers or vials. This kind of manufacturing brings both science and strict regulation together, as every batch must meet pharmacopoeial standards before reaching patients.
Budesonide’s therapeutic punch comes from adjustments to the core steroid scaffold. Introducing a cyclic acetal at the 16,17 position gives it extra fat-solubility—key for deep lung or gastrointestinal wall penetration. Certain chemical modifications help slow down metabolism, making sure doses remain active longer at their target. Down the research pipeline, scientists keep toying with substituent groups to nudge absorption rates, bioavailability, or to reduce unwanted systemic hits. For example, attempts at creating budesonide prodrugs aim to fine-tune release characteristics for colonic delivery in ulcerative colitis. Chemists bring a practical mindset here, balancing creativity and safety within regulatory boundaries.
Budesonide isn’t just one label on a shelf. It shows up under trade names like Pulmicort, Rhinocort, Entocort, and Uceris, each pointing toward a specific delivery form or disease. In reference labs, the name 16,17-(butylidenebis(oxy))-11β,21-dihydroxypregna-1,4-diene-3,20-dione appears on chemical inventory sheets. These synonyms usually reflect the context: clinical, regulatory, or supply-chain. The proliferation of brand names has helped providers pick the right application for the right setting, giving patients access to inhalers, nebulizers, nasal sprays, and oral formulations—each designed around the needs of specific diseases.
Drug safety experts put budesonide through the wringer at every stage. Patients and providers keep a close eye on dosing, especially for children, elderly, and people dealing with other health issues. Many inhaled steroids run the risk of oral thrush or hoarseness if users cut corners with inhaler maintenance, but thorough patient instruction and good mouth-rinsing habits shrink those risks. For workers handling the drug in factories, gloves, goggles, and dust masks are common, all to minimize accidental contact and inhalation during large-scale compounding. Storage routines—temperature logs, moisture controls, tamper-proof containers—protect both product and people. These routines have saved countless batches from spoilage and thousands of staff from unplanned exposures.
Budesonide stands out in treating asthma, chronic obstructive pulmonary disease, allergic rhinitis, eosinophilic esophagitis, and some forms of inflammatory bowel disease such as Crohn’s and ulcerative colitis. Its appeal grows out of targeted action: people can fight inflammation where it crops up, not everywhere at once. In respiratory care, inhaled forms keep patients out of the emergency room and bring relief with fewer side effects than oral steroids. In gastroenterology, budesonide capsules tackle inflammation directly in the intestines with minimal spillover into the bloodstream. It's also gaining traction in off-label uses—sometimes prescribed in rare lung diseases or immune conditions, under close specialist supervision. Doctors and patients alike know the difference between stumbling through flare-ups and enjoying daily life with less fear of setbacks.
Laboratories and clinical research centers keep asking tough questions about budesonide’s boundaries and new roles. Studies look at combinations with other drugs, like formoterol, for enhanced asthma management. Clinical trials push into new diseases and age groups, including infants with croup and adults fighting post-viral syndromes. Research into nanoformulations and controlled-release tablets aims to enhance absorption and patient convenience. Scientists look for genetic markers predicting response, hoping to spark a shift toward personalized medicine. Every incremental discovery aims to answer real patient needs, drive down side effects, and fine-tune therapy for both long-term control and short-term rescue.
Rigorous toxicity studies define budesonide’s safety profile. Inhaled forms mostly steer clear of the systemic risks tied to stronger corticosteroids, although high doses or long-term use still demand careful oversight. Animal studies and human trials have mapped the liver’s crucial role in breaking it down via cytochrome P450 enzymes, flagging drug interactions to watch out for. Chronic overdosing can push hormone imbalances or bone density loss into dangerous territory, so clinical guidelines stress monitoring, especially in growing children or older adults. Rare cases of adrenal suppression do show up, underscoring the need for tailored dosing and regular follow-up by health professionals who know every corner of a patient’s story.
The path forward for budesonide doesn’t taper off. Emerging research looks at smart inhalers tracking dose delivery, prodrugs tailored for tighter gastrointestinal targeting, and new uses in post-viral syndromes or bronchiectasis. Drug-device integration opens the door to better adherence and real-time monitoring, hopefully driving fewer relapses and ER visits. As the world faces resistant airway diseases, public health crises, and an aging population, budesonide’s role as a safe, accessible anti-inflammatory keeps drawing interest. Ongoing debates on sustainability and affordable access put added pressure on manufacturers to cut costs while keeping quality rock solid. Personalized dosing and digital health integration could drive a new era, making sure each patient gets not just the standard of care, but the care matched to their body’s shifting needs.
People around me wrestle with stuffy noses in allergy season, or battle a chesty cough that just won’t quit. Chronic sneezing, wheezing, difficulty catching a full breath—these are the signs of inflammation dragging someone down. Through work, school, and at home, I’ve seen folks miss out on daily life because their symptoms flare up. Doctors reach for proven answers in these situations. That’s where budesonide gets its place.
Budesonide works by calming irritated tissues in the airways or digestive tract. It belongs to the steroid family—similar to substances our bodies naturally make to control swelling and overreactions in the immune system. Inhalers, nasal sprays, and even pills give people a range of ways to get relief. For decades, kids and adults with asthma have relied on budesonide inhalers. These medicines help reduce tightness in the chest, cough, and labored breathing. Parents notice fewer night wakings with asthma attacks, and children can run without stopping to catch their breath. Every puff can mean a better day.
Crohn’s disease and ulcerative colitis create a different kind of misery. Gut inflammation leads to cramps, diarrhea, and weight loss that no amount of home remedies can fix. Budesonide capsules target the intestines, reducing swelling and letting people manage flare-ups. I’ve talked to people who finally return to travel, or share a meal without worry, thanks to the steady effect of this drug. This isn’t about miracles—it’s about manageable days and more normal routines.
A trusted doctor is key here. I’ve seen friends pick up over-the-counter nose sprays or leftover inhalers, but using them wrong leads to trouble—nosebleeds, fungal infections in the mouth, even weaker bones if used too much over time. Medical supervision may spot side effects early, like mood swings or weight gain, so adjustments can happen fast.
New options appear each year, from generic versions to combination products that mix budesonide with other supportive drugs. These help people who can’t manage with other medications—like children who can’t swallow pills, or asthma patients who need ultra-fine mists for sensitive lungs. At the same time, drug costs hit many family budgets hard. Insurance haggling and pharmacy shortages still put barriers in front of folks who just want a reliable supply. Community health clinics and advocacy groups work to fill gaps, but the struggle to pay for these important medicines continues.
Clinical studies show that budesonide, used regularly as prescribed, lowers the risk of emergency room visits and improves quality of life for people with chronic lung and gut conditions. Doctors review each person’s symptoms and medical history to decide if budesonide fits with their other treatments. Not everyone responds the same way, and some will need stronger medications. What stands true: people living with breathing troubles or gut distress should not give up on relief, and open conversations with healthcare providers can unlock a treatment plan that brings back control. Medicines like budesonide offer hope—when used with understanding and respect for the individual’s journey.
Budesonide shows up in prescriptions for asthma, ulcerative colitis, Crohn’s, and other inflammatory conditions. The drug, a corticosteroid, acts by calming down the body's overactive immune response. You might find budesonide as an inhaler, pill, or nasal spray, depending on your diagnosis. Most people don’t wake up worrying about side effects until they’re sitting with the pharmacy printout in hand. Reading the list can feel overwhelming and yet, missing the warning labels has its own cost.
Using budesonide, it’s not rare to find your mouth uncomfortably dry or you might end up with a raspy throat after repeated inhaler use. A friend of mine who takes it for asthma keeps a water bottle nearby at all times because the hoarseness made her self-conscious during meetings at work. Oral thrush—an overgrowth of yeast in the mouth—shows up on that side effect list, especially for those relying on inhalers and skipping the step of rinsing out their mouth after each dose. Rinsing doesn’t feel like much to ask, but missing it means dealing with painful white patches that can mess with taste and speaking.
People taking the pill version for stomach or intestinal diseases sometimes talk about headaches, stomach pain, or feeling a bit jumpy or shaky. These aren’t theoretical problems. A relative taking long-term budesonide for Crohn’s had trouble sleeping and felt jittery enough that cutting back on coffee became necessary. Weight gain and swelling in the face occasionally follow long-term use. These shifts sneak up, changing not just your mirror image but how you move through your day.
Steroids have a reputation for raising blood sugar, a bigger issue for people with diabetes or anyone with borderline glucose numbers. Regular blood work helps catch problems before they grow, but you can’t sense your sugar’s up just by feeling “off.” Children on budesonide over months might grow slower than peers. That’s a heavy concern for parents and something worth raising with their doctor, especially during check-ups.
Suppression of adrenal glands creates risks no one likes to talk about. The body gets used to help from the medicine and then doesn’t bounce back as quickly after stopping. A person who suddenly stops steroids, including budesonide, risks feeling weak or dizzy—a hard lesson learned by many who didn’t taper with their doctor’s guidance. Infection risk also rises because the immune system isn’t working at full tilt, so cuts or common colds might stick around longer than normal.
Getting the benefits of budesonide while staying ahead of side effects means sticking to the prescribed dose and schedule. Skipping or doubling up can do more harm than good. Using tools like spacers for inhalers and rinsing the mouth after each puff lowers the odds of thrush. For those on pills, regular check-ins with a doctor make it possible to catch changes early, like mood swings, higher blood pressure, or signs of infection.
Speaking up about every new symptom—even if it seems minor—keeps small problems from becoming big ones. Tracking how you feel in a notebook or phone app helped my friend catch a pattern between her late-night shakes and missed meals. Pharmacists give real-world tips and can answer questions that are tough to bring up with doctors. Budesonide helps millions breathe easier and live with less pain, but respect for the drug’s power goes a long way in keeping its risks under control.
Budesonide treats inflammation in the airways or gut, and doctors often recommend it for asthma, COPD, or conditions like Crohn's disease. My own family has relied on it for asthma attacks, which has meant learning the ropes of responsible medication use. The way someone uses budesonide really shapes how well it works and how safe it feels in daily life.
Jobs, school, or errands pack the schedule, and routines can go off the rails. Yet taking budesonide at the same time each day really pays off. My mother used to write reminders on sticky notes to avoid missing her inhaler doses. One missed puff may not seem like a big deal, but missing several opens the door to flare-ups or emergency room trips. Setting a phone alarm or placing medication near your toothbrush became habits we depended on.
Doctors match the delivery form to the problem at hand. Inhalers send medication straight to the lungs—a real lifesaver during breathless nights—while capsules or tablets address bowel inflammation. People sometimes forget the importance of rinsing the mouth after inhaling budesonide. I’ve seen relatives deal with mouth thrush from skipping this step. A simple rinse and spit each time cuts both discomfort and risk.
Swallowing tablets whole seems basic, but there’s temptation to crush or split pills to hide them in food. Budesonide relies on an outer coating to dissolve slowly at the spot where it works best. Breaking pills strips away this protection and reduces its impact, leaving symptoms stubborn and relief out of reach.
Using any steroid for weeks or months puts stress on the body. Some side effects—like changes in mood, sleep, or blood sugar—creep in without warning. I remember supporting a relative through mood swings tied to long-term steroid use, and honest talks with the doctor helped frame realistic expectations and make the bumpy road smoother. Reporting side effects quickly allows for dose adjustments, extra blood tests, or switching priorities.
Many people panic after realizing they missed a dose. Before rushing to double up, take a breath and follow medical advice. Most doctors suggest taking the missed dose as soon as it’s remembered, unless the next one is close at hand. Doubling up often leads to jitteriness, extra side effects, or clouded judgment—none of which support recovery. Once my brother tried to catch up on missed inhaler puffs—it left him shaking and uneasy, without any extra advantage.
Getting budesonide shouldn't break the bank. Yet insurance, pharmacy stock, or payment programs shape how families stay on track. Generics made the medication affordable for us after a switch in health plans left us scrambling. Some pharmacies offer coupons or work with doctors for alternatives, and drug companies set up patient assistance programs. Anyone struggling to pay should ask about these programs; keeping up the routine matters more than brand loyalty.
Using budesonide works best with steady routines, honest doctor visits, and regular attention to the body’s signals. Dropping the ball brings real risks, but clear habits and support systems keep things manageable. Each small step that makes dosing easier puts better health within reach—not just for people taking the medication, but for the families cheering them on.
Asthma does not hit pause during pregnancy. For women who depend on inhaled corticosteroids like budesonide, pregnancy brings out the worries. The whole idea of putting anything in your body while carrying a child gets an extra set of questions and anxieties. In my early days of managing asthma, I remember how much I relied on inhalers just to breathe freely. Being told to stop a medication during pregnancy can feel unsettling, especially if breathing struggles are already part of daily life.
Doctors lean on facts before recommending anything for pregnant women. Modern studies show inhaled budesonide does not appear linked with serious birth defects or big pregnancy risks. The National Asthma Education and Prevention Program (NAEPP) and a ton of guidelines point out that budesonide stands out as a preferred corticosteroid for women who cannot keep asthma in check through lifestyle changes alone. These guidelines did not pop up overnight. Big research efforts, such as those reviewing thousands of women and their pregnancy outcomes, support these conclusions. The Scandinavian Medical Birth Register, including Swedish and Danish pregnancies, tracked women using budesonide and found no higher risk of malformations in their children compared to the general population.
Pregnancy grows more complicated when asthma becomes poorly controlled. The real danger comes from oxygen not reaching the baby—a risk far greater than what experts see with inhaled corticosteroids. The CDC showed that women with severe asthma attacks during pregnancy face higher rates of preterm birth and low birth weight. Safe breathing often keeps both mother and baby in better health.
Every case looks different. One woman may experience milder symptoms that improve during pregnancy, while another might see her asthma flare unpredictably. Open, honest talks with doctors make the biggest difference. Many specialists will prefer budesonide over other steroids because it does not seem to spread as widely through the body after inhalation, reducing the chances of side effects for the growing baby.
Drug labeling in the United States lists budesonide as Category B for pregnancy. Animal studies did not reveal harm, yet there are always questions about translating lab data to real life. For mothers who have already tried to cut back and still wake up wheezing or breathless, staying on treatment remains important. Risking an asthma attack, needing emergency visits, or facing low oxygen levels has shown to be worse for babies than using a proven inhaler every day.
Support and education often ease the anxiety. Expecting mothers benefit most when information is straightforward—facts about risks, benefits, and alternatives laid out clearly so nobody feels like they are guessing. Nurses, pharmacists, and asthma educators can play an essential role. Written asthma action plans, regular check-ups, and honesty about symptoms help keep everyone safe. Doctors typically start with the lowest dose that keeps symptoms away, revisiting the treatment plan throughout the pregnancy. This balance often reassures mothers who are torn between worry and well-being.
Budesonide will not fit every situation. But real-world use, strong science, and the guiding hand of experienced doctors keep things safer for families. Honest conversation, patient education, and a clear plan make the difference for mothers who want the best for themselves and their children, breathing easier along the way.
Ask anyone who’s picked up a prescription for asthma or allergies, and chances are they’ve seen the word Budesonide somewhere on the package. Plenty of folks get a little nervous seeing “steroid” on their medicine bottle. In everyday conversations, “steroids” conjure up images of muscle-bound athletes or risky side effects. Here’s the thing: Budesonide plays a big role in modern medicine, doing quiet but essential work for people who need to breathe a little easier or calm down their gut when it’s flaring up.
Budesonide falls squarely into the category of corticosteroids, not the anabolic steroids that make headlines in sports scandals. Corticosteroids mimic hormones your body turns out in your adrenal glands, dialing down inflammation without the drama linked to “performance enhancers.” I’ve met parents who worried when their kid’s doctor prescribed budesonide for croup or asthma, picturing side-effects from muscle shakes to angry moods. In practice, this medicine’s real skill lies in calming down parts of the body that have gone off the rails with inflammation.
Inhaled budesonide often shows up as a rescue for kids and adults dealing with chronic coughs or tightness in their chest. It works right where it lands—in the lungs or nose—reducing the body’s over-the-top response to ordinary stuff like pollen or dust. Most people using an inhaler or nasal spray containing budesonide never lose sleep over long-term risks, because doctors keep doses low and monitor carefully. Studies in medical journals back up its effectiveness, showing that routine use in inhaled form leads to fewer severe asthma attacks and fewer trips to the emergency room.
Beyond allergies and asthma, budesonide has found a valuable niche in treating stubborn gut diseases. People with Crohn’s disease or ulcerative colitis often cycle through medicines that come packed with tough side effects. Oral budesonide gives targeted relief, focusing on the inflamed area without exposing the whole body to high steroid doses. My own experience working with patients managing Crohn’s points to the importance of this targeted approach—people feel better, bounce back faster, and cope with fewer complications.
Nobody wants to take more medicine than necessary, and the word “steroid” understandably sets off alarms. Short-term use of budesonide rarely causes the weight gain, mood swings, or bone thinning seen with long-term oral steroids. Still, regular check-ins with healthcare professionals stay important. For instance, children using inhaled budesonide over a long stretch may need occasional growth checks to rule out even minor side effects.
Education feels like the best way to cut through misunderstandings around medicines like budesonide. Pharmacists, family doctors, and specialists spend a lot of time walking patients through the difference between corticosteroids and the kind that alter physical appearance. Trusted sources—including the FDA, CDC, and research published in The Lancet—stand ready to reassure anyone with doubts: at the recommended doses, budesonide offers benefits with much lower risk than older, systemic steroids. Simple conversations and honest, practical advice go further than jargon or outdated fears.
| Names | |
| Preferred IUPAC name | (1S,2S,4R,6S,8S,9R,10S,13S,14S,16R,17R)-16,17-Butanedioxy-6,10,13-trimethyl-1,2,4,8,9,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione |
| Other names |
Budenofalk
Entocort Pulmicort Rhinocort Symbicort |
| Pronunciation | /bjuːˈdɛsənaɪd/ |
| Preferred IUPAC name | (1S,2S,4R,6S,8S,9R,10S,13S,14S,16R,17R)-16,17-Butanedioyl-6,9-difluoro-11,21-dihydroxy-10,13-dimethyl-1,2,4,8,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one |
| Other names |
Entocort
Pulmicort Rhinocort Symbicort Uceris Cortiment |
| Pronunciation | /ˌbjuːdɪˈsoʊnaɪd/ |
| Identifiers | |
| CAS Number | 51333-22-3 |
| Beilstein Reference | 3580432 |
| ChEBI | CHEBI:3203 |
| ChEMBL | CHEMBL1433 |
| ChemSpider | 54816 |
| DrugBank | DB01222 |
| ECHA InfoCard | 04e6c9ff-04e7-4b43-931e-d765becc3e27 |
| EC Number | EC 3.1.3.16 |
| Gmelin Reference | 94637 |
| KEGG | D00968 |
| MeSH | D009978 |
| PubChem CID | 5280725 |
| RTECS number | VX0886000 |
| UNII | SY2BF58YCB |
| UN number | UN2811 |
| CAS Number | 51333-22-3 |
| 3D model (JSmol) | `3D model (JSmol) string` for Budesonide: ``` C1C(C2C(CC1(C3=CC(=O)C=CC3(C2(C(=O)CO)O)C)C)O)C(F)(F)C ``` |
| Beilstein Reference | 130339 |
| ChEBI | CHEBI:31420 |
| ChEMBL | CHEMBL1436 |
| ChemSpider | 39340 |
| DrugBank | DB01222 |
| ECHA InfoCard | EC Number: 254-484-5 |
| EC Number | 602-093-0 |
| Gmelin Reference | 92619 |
| KEGG | D00246 |
| MeSH | D017918 |
| PubChem CID | 5280725 |
| RTECS number | BUK520A84Y |
| UNII | 03L9OT429T |
| UN number | UN3248 |
| Properties | |
| Chemical formula | C25H34O6 |
| Molar mass | 430.539 g/mol |
| Appearance | White to almost white powder |
| Odor | Odorless |
| Density | 1.24 g/cm3 |
| Solubility in water | Practically insoluble in water |
| log P | 2.2 |
| Vapor pressure | 2.6 × 10⁻⁹ mmHg |
| Acidity (pKa) | 14.54 |
| Basicity (pKb) | 12.29 |
| Magnetic susceptibility (χ) | -78.1e-6 cm³/mol |
| Refractive index (nD) | 1.230 |
| Viscosity | Viscosity: 25-50 cps |
| Dipole moment | 2.45 D |
| Chemical formula | C25H34O6 |
| Molar mass | 430.538 g/mol |
| Appearance | White to off-white powder |
| Odor | Odorless |
| Density | 1.3 g/cm³ |
| Solubility in water | Insoluble in water |
| log P | 2.62 |
| Vapor pressure | 2.6 x 10^-9 mmHg |
| Acidity (pKa) | 13.73 |
| Basicity (pKb) | 12.23 |
| Magnetic susceptibility (χ) | -75.9e-6 cm³/mol |
| Refractive index (nD) | 1.230 |
| Dipole moment | 2.45 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 324.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -882.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -7115 kJ/mol |
| Std molar entropy (S⦵298) | 673.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -1241.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -6866 kJ/mol |
| Pharmacology | |
| ATC code | R03BA02 |
| ATC code | R03BA02 |
| Hazards | |
| Main hazards | May cause immunosuppression, adrenal suppression, increased risk of infections, osteoporosis, and, rarely, psychiatric effects. |
| GHS labelling | GHS02, GHS07 |
| Pictograms | {"anti-inflammatory":"✔️","glucocorticoid":"✔️","asthma":"✔️","nasal spray":"✔️","inhalation":"✔️","pregnancy caution":"⚠️","children caution":"⚠️","not for acute attack":"⛔"} |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | P101 If medical advice is needed, have product container or label at hand. P102 Keep out of reach of children. P103 Read label before use. |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 329.1°C |
| Autoignition temperature | 460°C |
| Explosive limits | Not explosive |
| Lethal dose or concentration | LD50 (Rat, oral): >2000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse oral LD50 = 200 mg/kg |
| NIOSH | GNF4782K19 |
| PEL (Permissible) | PEL not established |
| REL (Recommended) | 0.2–0.6 mg/m³ |
| IDLH (Immediate danger) | Not listed. |
| Main hazards | May cause allergic reactions, immunosuppression, adrenal suppression, growth retardation in children, increased risk of infections, and, with long-term use, osteoporosis, glaucoma, or cataracts. |
| GHS labelling | GHS07; GHS08; WARNING |
| Pictograms | medicinal-product|inhalation|prescription-only|anti-inflammatory |
| Signal word | Warning |
| Hazard statements | H410: Very toxic to aquatic life with long lasting effects. |
| Precautionary statements | Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Use only as directed by your doctor. Do not use this medication if you are allergic to budesonide or any of its ingredients. |
| NFPA 704 (fire diamond) | 1-0-0-NA |
| Flash point | 224.6 °C |
| Lethal dose or concentration | LD50 (rat, oral): > 2000 mg/kg |
| LD50 (median dose) | LD50 (median dose) of Budesonide: "131 mg/kg (rat, oral) |
| NIOSH | ANW8VAI85K |
| PEL (Permissible) | Not Established |
| REL (Recommended) | 0.128 mg |
| IDLH (Immediate danger) | No IDLH established. |
| Related compounds | |
| Related compounds |
Dehydroepiandrosterone
Hydrocortisone Prednisolone Prednisone Cortisone Dexamethasone Methylprednisolone Triamcinolone Fluticasone Beclometasone |
| Related compounds |
Desisobutyryl budesonide
Budesonide acetate Fluticasone propionate Mometasone furoate Ciclesonide Beclometasone dipropionate Triamcinolone acetonide |
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