Fludrocortisone acetate came out of a long search for effective synthetic mineralocorticoids, tracing its roots to mid-20th-century work in adrenal hormone research. Researchers looked beyond natural steroids, isolating compounds that control sodium and potassium in the body. The arrival of fludrocortisone shifted the landscape for conditions like Addison's disease. Fludrocortisone took a prominent place because it gave doctors a way to manage adrenal insufficiency without turning to high doses of corticosteroids, which came with their own set of complications. Scientists didn’t stumble on it overnight—getting from bench to bedside took years of testing, setbacks, and perseverance.
Fludrocortisone acetate, usually sold in tablet form, has a consistent role in treating Addison's disease and certain forms of congenital adrenal hyperplasia. The medicine, classified as a synthetic corticosteroid, mimics the effects of aldosterone, helping keep sodium levels and blood pressure in check. While other corticosteroids get plenty of headlines for their use in inflammation, this one occupies a unique spot as a mineralocorticoid, filling a key therapeutic need for a relatively small group of patients. Its reach isn’t broad, but for those who need it, fludrocortisone can make a difference that goes far beyond symptom relief.
Fludrocortisone acetate appears as a white or off-white crystalline powder that doesn’t dissolve easily in water. Its molecular formula is C23H31FO6, and the compound weighs in with a molecular mass of 422.49 g/mol. Melting points hover around 255–265°C. The presence of the acetate group and the fluorine atom on the steroid backbone makes it stand apart from hydrocortisone and other corticosteroids. It resists rapid breakup under normal storage, maintaining stability under dry, cool conditions. Every detail—from melting point to solubility—stems from its deliberate chemical tinkering, not just luck.
Manufacturers must nail technical criteria to meet health authority approval. USP standards or relevant pharmacopeia set the benchmark for purity, dosage accuracy, and contaminant levels. Tablet formulations usually deliver fludrocortisone acetate at 0.1 mg per unit, often mixed with fillers and binders to guarantee strength and shelf life. Labels need to declare the exact dosage and contain clear instructions for storage, side effects, and usage warnings. Pharmacies often double-check for allergens or unnecessary fillers, catering to sensitive patient populations.
Synthesis calls for several steps, beginning with a suitable corticosteroid backbone such as hydrocortisone. Chemists introduce a fluorine atom at the 9α position, which ramps up mineralocorticoid activity. After that, they attach an acetate group at the 21st position with standard acylation reactions. Each step must run with tight controls to avoid unwanted byproducts or loss of function, which can easily slip in if someone cuts corners on temperature or reagent quality. The final product goes through purification and crystallization before it’s pressed into tablets or filled into vials for other dosage forms.
Tweaking fludrocortisone’s core often focuses on the acetyl group or fluorine atom. Swapping or removing these chemical features alters potency and side effects. The introduction of fluorine pivots the compound’s activity toward sodium retention, leaving glucocorticoid activity as a secondary effect. Most modifications aim to raise selectivity, but few have made it into regular clinical use. The acetate ester boosts the compound’s stability until it encounters the body’s enzymes, making the drug more predictable in its therapeutic action.
Doctors and pharmacists recognize fludrocortisone acetate by several names. Its best-known trade name, Florinef, has made its way into formularies worldwide. Scientific papers sometimes refer to it as 9α-Fluoro-11β,17α,21-trihydroxypregn-4-ene-3,20-dione 21-acetate. The name may sound unwieldy, but it describes every twist and turn in the molecule’s structure. Different regions use local brand names, but the active substance remains the same, standardized for quality and potency.
Using fludrocortisone acetate comes with firm safety rules. Health professionals train to watch for warning signs of fluid overload or high blood pressure, especially in the elderly and those with preexisting heart or kidney troubles. Clear protocols keep dosing within safe limits, and regular checkups track shifts in electrolytes. Pharmacies and manufacturing plants set up strict contamination controls and quality assurance steps from raw input to final release. Safety data sheets outline handling guidelines and disposal rules. Every stage, from synthesis to administration, relies on experience-backed judgment to reduce mistakes and harm.
Fludrocortisone acetate finds use mostly in the endocrine clinic, where doctors prescribe it for adrenal insufficiency and some rare salt-wasting disorders. It takes a front-row spot in treating Addison’s disease, helping restore the body’s missing ability to balance sodium. Pediatric endocrinologists turn to it for children with congenital adrenal hyperplasia, where salt loss threatens normal growth and development. Research occasionally explores off-label uses—such as for orthostatic hypotension—but mainstream medicine keeps its use focused on mineralocorticoid replacement.
Modern research keeps probing the edges of fludrocortisone’s potential. Teams look at dosing strategies, alternative delivery methods, and effects in rare autoimmune diseases that affect the adrenal gland. Efforts have reached into tweaking the molecule for even more precise action, building analogs with reduced side effects. Advanced clinical trials still highlight the challenges of small patient populations and finding reliable biomarkers to tailor therapy. New analytic methods, such as mass spectrometry, now help track metabolism and breakdown in the body with more clarity than ever before.
Exploring toxicity starts with the simple fact that mineralocorticoids can strain the heart and kidneys if overused. Researchers study dose-response relationships, electrolyte imbalances, and long-term impacts of low but chronic overexposure. Animal studies show how excess drug builds up in tissues, while patient registries supply insight into real-world adverse events. Some researchers worry about rare but serious complications like heart rhythm disturbances or weakening of bones. Regular lab checks and close follow-up remain the main safety net for patients, guided by a growing body of clinical and preclinical data.
Fludrocortisone acetate won’t disappear from the medicine cabinet soon. Demand persists as long as people face adrenal disorders or rare salt-losing conditions. Researchers search for new delivery forms to improve convenience, patient adherence, and lower the risk of spikes or drops in hormone effect. Genetic studies may eventually guide personalized dosing for maximal benefit and minimal risk. There’s curiosity about how this old drug could fit into broader treatment programs and new disease indications. Continuing work on the chemistry could open doors to next-generation compounds with the same mineralocorticoid punch but fewer side effects. From my own experience seeing patients turn their lives around, there’s clear value in both improving what’s on hand and exploring what’s next.
Fludrocortisone acetate belongs to a group of medications called corticosteroids. Doctors rely on it for a specific purpose: it helps the body regulate salt and water balance. Many people live with health conditions where this balance turns into a daily struggle. One of the main conditions treated with fludrocortisone acetate is Addison’s disease. This illness means the adrenal glands just don’t produce enough hormones, including one called aldosterone. Without enough aldosterone, the body loses sodium, holds onto too much potassium, and struggles to keep blood pressure steady. Fludrocortisone steps in to fill that gap.
Anyone who’s experienced dehydration or seen an electrolyte panel can appreciate just how easily things go wrong in the body without the right salt levels. For people with Addison’s disease and similar issues, legs can cramp, blood pressure can bottom out, and basic daily life feels like running uphill. Fludrocortisone acetate acts almost like a replacement key, unlocking pathways that tell the kidneys to hold onto sodium. This action supports normal blood volume and keeps blood pressure from dropping dangerously low.
Beyond Addison’s disease, doctors sometimes turn to fludrocortisone for other conditions, like congenital adrenal hyperplasia. Children born with this disorder struggle to make hormones at all, growing up frail and at risk for life-threatening crises. Fludrocortisone and salt supplements together help these kids grow, play, and live much more normally. In rare cases, doctors use this medication to help people with certain types of low blood pressure not related to adrenal disease.
No solution comes without trade-offs. Taking fludrocortisone can lead to fluid retention, swelling, high blood pressure, and sometimes low potassium. Many patients need regular blood tests to make sure their potassium isn’t dropping, and doctors adjust the dose to the minimum that works. From what I’ve seen, people on this medication often need salt in their diet, sometimes far more than average. Fludrocortisone can cause problems with long-term use, like weakening of bones, so most doctors keep a close watch over their patients with a routine that involves both chemistry panels and follow-up visits.
Many patients need to learn how to adjust their medication if they get sick, travel, or have surgery. Infections, stress, or dehydration can quickly spiral into a crisis for those who depend on corticosteroid replacement. Educating families and patients matters just as much as the prescription itself. Many support groups and educational materials exist for people living with adrenal problems, connecting families with information, encouragement, and advice.
Fludrocortisone acetate can make a dramatic difference in quality of life. Reliable access to this medication remains essential. For many families, cost or shortages create anxiety. Community pharmacies and specialty clinics can play a role by monitoring stock and coordinating refills. Better patient education about warning signs of salt loss, stress dosing during illness, and the role of extra salt in the diet all contribute to safer use of the drug. Some research into longer-acting or alternative treatments might spare patients from the daily worries, but fludrocortisone remains the mainstay today for many adrenal conditions.
Living with Addison’s or related disorders turns salt and water into daily concerns that most people never have to think about. Fludrocortisone acetate offers hope and support, helping many folks go about their lives with far fewer interruptions from their illness.
Many folks hear “steroid medication” and brace themselves. Fludrocortisone acetate, a mouthful of a name prescribed mostly for adrenal issues like Addison’s disease, doesn’t fall far from that tree. It’s true—this tiny pill can make a big impact, both good and bad. Knowing what to expect helps people feel less anxious before a doctor visit and much more prepared to speak up if something feels off.
Right out of the gate, increased blood pressure shows up as one of the top complaints. Salt and water hang around in the body longer than usual, which pushes up blood volume. It’s not just a number on a chart, either. Headaches, flushed cheeks, tightness around the temples—these signs should never get brushed off, especially for anyone already tracking their heart health.
Swelling creeps in thanks to that same salt and water retention. Ankles puff up, rings start fitting a little too tightly, and sometimes eyes look puffy in the morning. For people with existing heart or kidney concerns, this symptom can become dangerous in a hurry.
Feeling off-balance or dizzy may surprise some people. Extra water in the system throws off normal rhythms and zaps energy. I remember one patient who was steady on his feet before starting fludrocortisone and suddenly found himself stumbling by the end of week one.
Another issue worth mentioning: muscle weakness. Muscles need a precise mix of minerals to stay strong; this medication can flush out potassium. That leads to tired arms, legs that cramp up at night, or hands that shake with less weight than before.
The body’s natural cortisol swings can get thrown out of step with chronic steroid use. People have told me about mood swings that feel like a roller coaster—snapping at loved ones one minute, tearing up for no reason the next. Mood shouldn’t change this much, which is why doctors check in about mental health just as often as physical health.
Stomach discomfort sometimes slips under the radar. Nausea, a burning feeling after eating, or more frequent hunger live on the list—especially if people skip meals or combine their dose with coffee instead of food.
A few people, especially kids, mention slowed growth or delayed healing after a scrape. The body diverts resources to adjust for the medicine, and little things that used to patch up quickly might stick around longer than expected.
Smarter nutrition can ease the strain. Low-salt diets fight back against swelling and high blood pressure, and eating foods rich in potassium like bananas or sweet potatoes may help stop muscle cramps. Doctors usually monitor blood work closely, watching for dips in potassium and telling people when they need a supplement.
Honest conversations with healthcare teams make a world of difference. Any sign of swelling, headaches, irregular heartbeat, or mood changes deserves attention. I’ve seen people lift a burden from their shoulders just by saying out loud how a medication makes them feel. Early action can prevent bigger issues down the road.
It comes down to paying attention and speaking up. Fludrocortisone has a vital place in medicine cabinets but doesn’t have to leave someone guessing about every strange symptom. Treatment works best when it fits the person, not just the diagnosis.
Fludrocortisone Acetate, usually called “fludro” in clinics, doesn’t make headlines, but for people with adrenal insufficiency or Addison’s disease, this medication keeps life steady. Missing a dose, taking it at the wrong hours, or not pairing it with the right habits can mean major trouble. I’ve watched family members rely on it, learning firsthand that it’s not just another prescription—it’s a lifeline that calls for respect and real discipline.
Doctors usually hand out a plan tailored to your body. Most often, fludrocortisone comes as a small tablet swallowed once daily. Patients take it at the same time every morning—this sets a rhythm. Food doesn’t block it, but eating right after swallowing can help ease any nausea. Skipping or doubling up at random can put stress on the heart or throw salt levels out of balance. The package doesn’t always spell out what a sudden salty craving means or why a little headache might matter, but every symptom tells a story when you’re on this drug.
Blood pressure checks at home become a ritual for anyone serious about staying healthy on fludrocortisone. Extra salt may get added to the diet, especially in the heat or after intense exercise. Potassium keeps dropping, so fruit like bananas or a handful of spinach gets a new relevance. The routine also demands an eagle eye on swelling in the legs or headaches that just won’t quit—signals that salt and water in the body need adjusting. To ignore these signs is to invite a crisis.
Fludrocortisone gets better results when the patient speaks up. I’ve watched friends get far from the hospital before mentioning muscle weakness or chest flutters, thinking it was just stress. Open calls with a healthcare team matter. Every adjustment—up or down—starts with a real conversation, not a gut feeling. Lab work checks sodium, potassium, and kidney numbers every few months. Some people keep notes in a phone, others jot them on sticky paper, but no one trusts memory with a medicine this important.
Travel throws curveballs, especially crossing time zones. Packing extra doses and keeping pills in hand luggage beats searching pharmacies abroad. Missing just one can bring on fatigue or a dangerous drop in blood pressure. During illness or heavy flu seasons, some people double-check with their doctor about dose changes. Any surgery puts extra pressure on the adrenal glands, so medical staff need a heads-up before the big day.
Education sits at the root of safe fludrocortisone use. It’s never a one-time meeting; reminders help catch side effects early. Support groups, often online, let people swap practical advice about overcoming cravings, reading food labels, and building routines that stick. Pharmacists can spot medicine clashes early, so a simple phone call can dodge mistakes with blood pressure tablets or anti-inflammatories.
Fludrocortisone keeps bodies running in tough conditions, but only if folks treat it as more than a pill. Strict routines, honest reporting, regular check-ups, and partnership with medical teams bring the best results. I’ve seen how lives balance on these habits, turning a prescription into peace of mind—not just numbers in a medical chart.
Fludrocortisone acetate often finds a spot in treatments for conditions like Addison’s disease or salt-losing syndromes. It works by mimicking the body’s own hormones, helping keep blood pressure and salt balance in check. But its usefulness doesn’t block out the chance for trouble, especially when mixed with other drugs. Sometimes patients and even busy doctors forget that a medicine as valuable as this can still stir up unwanted reactions when combined with others.
One combination that makes me pause is fludrocortisone and certain diuretics—like furosemide or hydrochlorothiazide. Diuretics help the body shed extra water and salt. Fludrocortisone, on the other hand, tries to help the body hold onto sodium. This tug-of-war over how much salt to keep can throw potassium levels into chaos. Too little potassium triggers problems like muscle cramps and irregular heartbeats. Many people never think much about their potassium until one of these symptoms crops up and the lab results spell it out.
Then there’s warfarin, a blood thinner. Mixing fludrocortisone with warfarin can sometimes change how the body processes the thinner, throwing off INR results and forcing dose changes. I’ve seen patients bounce between clotting and bruising when these adjustments aren’t taken seriously.
Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen often seem harmless since they’re sold over the counter. But toss these into the mix with fludrocortisone, and the risk of fluid retention, raised blood pressure, and kidney problems grows. This hits seniors the hardest, especially those with a weak heart or worn-out kidneys.
Some antifungal meds, like ketoconazole, can ramp up fludrocortisone levels in the body. The consequences can sneak up: swelling, high blood pressure, or even a racing heart from too much hormone circulating. Then there’s diabetes medication. Fludrocortisone can make blood sugar harder to control, leading people to adjust their insulin or pills more frequently than usual.
Open communication with healthcare providers cuts down a lot of the risk. People should feel comfortable carrying a list of everything they take—including vitamins and herbs. Those regular check-ins and lab work aren’t just busywork—they’re what helps spot trouble before it gets ugly. Pharmacists can catch problems, especially if the same person fills every prescription.
The need for patient education keeps coming up. Too many people think side effects only come from “strong” or new drugs, not realizing that even familiar over-the-counter pills interact with prescription medications. Staying curious, asking pharmacists questions, and reading everything that comes with a prescription bottle all help.
On the medical side, computerized alert systems flag risky drug combinations. Even seasoned providers overlook things sometimes, especially in a busy practice. These systems fill in those gaps, nudging doctors and nurses to take a second look before sending a patient home.
Drug interactions aren’t just a line in the fine print—they’re a real-life issue that affects outcomes, safety, and stress. Every time a new doctor or specialist steps in, medication lists should be reviewed. In my own circle, I’ve seen how staying organized—with a simple chart or even a smartphone app—lets people notice patterns their providers might miss.
Fludrocortisone acetate, while essential for some, demands respect when it comes to mixing with other medications. Open discussion, careful monitoring, and a healthy dose of curiosity often make the biggest difference in keeping treatment safe and effective.
Doctors prescribe fludrocortisone acetate for a handful of rare health conditions, most often Addison’s disease and other adrenal gland disorders. This medication keeps salt and water levels in balance, which protects blood pressure from crashing. People who live with adrenal insufficiency—myself included for a few years—know how these pills become a lifeline.
Pregnancy upends daily routines, but folks managing chronic conditions like adrenal insufficiency face extra hurdles. The safety of medications turns into a central concern. Fludrocortisone sits in a grey zone because good studies in pregnant people remain scarce.
Older textbooks label the drug as pregnancy category C. That means animal research turned up some problems at high doses, yet strong evidence in humans is missing. Doctors sometimes keep patients on fludrocortisone during pregnancy, especially if stopping it risks adrenal crisis—a situation that clearly endangers both mom and baby. According to the National Organization for Rare Disorders, missing fludrocortisone raises the risk of low blood pressure, dizziness, vomiting, and even hospitalization. Not taking it may prove riskier than the theoretical drug side effects.
Real decisions about using drugs during pregnancy usually involve tough trade-offs. Expectant mothers with Addison’s disease or congenital adrenal hyperplasia need these hormones to avoid disaster. Most endocrinologists recommend the lowest effective dose—enough to keep symptoms controlled. I’ve met parents who worked side-by-side with their doctors every few weeks, tweaking the dose as their bodies and babies changed. Regular checkups, extra blood work, and frank conversations shaped a safer path.
So far, case reports and specialist experience reveal no consistent pattern of birth defects linked to fludrocortisone in pregnancy. Still, the absence of big, controlled studies means we move forward on a narrow ledge.
After childbirth, new parents sometimes ask whether fludrocortisone passes into breast milk. Official guidelines suggest that traces can show up, but there’s no solid proof that the tiny amounts harm nursing babies. LactMed, a database run by the U.S. National Library of Medicine, mentions fludrocortisone appears at low levels in milk, especially at standard doses. Pediatricians have rarely reported side effects in infants nursing from mothers taking their prescribed medication. In my advocacy group, mothers often kept breastfeeding with their endocrinologist looped in, watching for any baby trouble like poor weight gain.
Pregnancy and breastfeeding both stir up deep anxieties about what’s best for the child. Clear, honest conversations matter most. Women living with adrenal disorders count on providers with both expertise and empathy. They want information rooted in facts but filtered through real-life experience. Shared decision-making works best: weighing risks and listening to everyone’s concerns. Every parent and doctor faces a slightly different puzzle, shaped by genetics, health needs, and family priorities.
Fludrocortisone isn’t a mainstream drug, so pregnancy and breastfeeding safety may not appear in flashy headlines. But for families caught in these rare situations, answers mean everything. Better research will help. Until then, steady partnerships between patients and medical teams provide the safest bridge across uncertain ground.
| Names | |
| Preferred IUPAC name | [(8S,9α,10S,11β,13α,14α,17α)-9-Fluoro-11,17-dihydroxy-17-(2-acetoxyacetyl)-10,13-dimethyl-2,6,7,8,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one] |
| Other names |
Florinef
19-Norhydroxycorticosterone acetate Fludroxycortide acetate Fludrocortisonum Aceticum |
| Pronunciation | /ˌfluːdrəʊˈkɔːrtɪˌsoʊn ˈæsɪteɪt/ |
| Preferred IUPAC name | (1R,2S,10S,11S,13R,14S,15S,17S)-17-(2-acetyloxyacetyl)-11,17-dihydroxy-14,15-dimethyl-6-fluoro-2,13,15,16-tetrahydro-1H-cyclopenta[a]phenanthren-3-one |
| Other names |
9α-Fluoro-11β,17α-dihydroxy-21-acetoxy-pregn-4-ene-3,20-dione
Florinef Florinef Acetate 9α-Fluorocortisol acetate |
| Pronunciation | /fluːˌdrəʊˌkɔːˈtɪsəˌn æˈsiːteɪt/ |
| Identifiers | |
| CAS Number | 514-36-3 |
| Beilstein Reference | 1771097 |
| ChEBI | CHEBI:4413 |
| ChEMBL | CHEMBL1200315 |
| ChemSpider | 23243718 |
| DrugBank | DB00687 |
| ECHA InfoCard | echa.europa.eu/infocard/100013960519 |
| EC Number | 5.3.1.9 |
| Gmelin Reference | 3853 |
| KEGG | C07276 |
| MeSH | D005473 |
| PubChem CID | 62952 |
| RTECS number | BS5050000 |
| UNII | K4E0546XIY |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID6020189 |
| CAS Number | 514-36-3 |
| Beilstein Reference | 3568732 |
| ChEBI | CHEBI:4463 |
| ChEMBL | CHEMBL1200308 |
| ChemSpider | 2158 |
| DrugBank | DB00687 |
| ECHA InfoCard | 03f713ff-5d7b-434d-9a7c-51330188c650 |
| EC Number | 206-984-3 |
| Gmelin Reference | 85206 |
| KEGG | C07376 |
| MeSH | D005473 |
| PubChem CID | 60713 |
| RTECS number | UF8850000 |
| UNII | W968Q1I43Y |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID5020328 |
| Properties | |
| Chemical formula | C23H31FO6 |
| Molar mass | 558.661 g/mol |
| Appearance | White or almost white, crystalline powder |
| Odor | Odorless |
| Density | 1.39 g/cm³ |
| Solubility in water | Slightly soluble in water |
| log P | 0.87 |
| Acidity (pKa) | 12.35 |
| Basicity (pKb) | 12.21 |
| Magnetic susceptibility (χ) | -7.9e-6 |
| Refractive index (nD) | 1.540 |
| Viscosity | Viscous liquid |
| Dipole moment | 2.45 D |
| Chemical formula | C23H31FO6 |
| Molar mass | 452.49 g/mol |
| Appearance | White or almost white, crystalline powder |
| Odor | Odorless |
| Density | 1.55 g/cm³ |
| Solubility in water | Slightly soluble in water |
| log P | 0.7 |
| Vapor pressure | <0.0000001 mm Hg (25°C) |
| Acidity (pKa) | 12.49 |
| Basicity (pKb) | 12.49 |
| Magnetic susceptibility (χ) | -8.87e-7 |
| Refractive index (nD) | 1.540 |
| Dipole moment | 2.73 D |
| Pharmacology | |
| ATC code | H02AA02 |
| ATC code | H02AA02 |
| Hazards | |
| Main hazards | May be harmful if swallowed, causes serious eye irritation, may cause an allergic skin reaction |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. |
| Precautionary statements | P264, P270, P301+P312, P330, P501 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | > 307.9 °C |
| Explosive limits | Non-explosive |
| Lethal dose or concentration | LD50 oral (rat) 1100 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse oral 8 mg/kg |
| NIOSH | SF8575000 |
| PEL (Permissible) | PEL (Permissible) : N/L (PEL) (OSHA) |
| REL (Recommended) | 50 micrograms |
| IDLH (Immediate danger) | Not established |
| Main hazards | May be harmful if swallowed, causes eye and skin irritation, may cause reproductive or developmental toxicity |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. H319: Causes serious eye irritation. H361: Suspected of damaging fertility or the unborn child. |
| Precautionary statements | Do not store above 25°C. Keep container tightly closed. Keep out of the reach and sight of children. For oral use only. Use only as directed by a physician. |
| Flash point | 170.8 °C |
| Lethal dose or concentration | LD50 oral (rat) 2 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral, rat: 300 mg/kg |
| NIOSH | SA0125000 |
| PEL (Permissible) | PEL (Permissible exposure limit) for Fludrocortisone Acetate: Not established. |
| REL (Recommended) | 0.1 mg |
| Related compounds | |
| Related compounds |
Cortisone
Fludrocortisone Fluorocortisone Hydrocortisone Prednisolone |
| Related compounds |
Hydrocortisone
Cortisone Prednisolone Methylprednisolone Dexamethasone Betamethasone Triamcinolone Fluocinolone acetonide |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 747.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of combustion (ΔcH⦵298) | -8021 kJ/mol |
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