Flumethasone hasn’t always been a household name, even among healthcare workers, but its story holds weight in the evolution of synthetic corticosteroids. Early on, researchers noticed natural corticosteroids like cortisone changed the course for inflammatory diseases, but the search never stopped for more potent, less toxic alternatives. Flumethasone emerged in the 1960s, after chemists made structural tweaks to traditional steroids by adding fluorine atoms and double bonds. This new compound changed the game in treating stubborn skin disorders and allergic reactions in both people and animals. As the medical world grew more cautious about steroid use, researchers crafted dosing schedules and new synthetic versions to give patients strong anti-inflammatory effects with fewer side effects. For anyone knee-deep in clinical medicine or veterinary practice, it’s clear the development of flumethasone marks a turning point in how doctors handle tough inflammatory conditions.
Flumethasone comes to market in a range of forms: creams, ointments, tablets, and injections for both human and animal medicine. Every product features the same synthetic glucocorticoid backbone but gets formulated to work best on skin, in the bloodstream, or for some animal diseases. In its pure state, flumethasone serves as the active ingredient, but in practice, different brands blend it with carriers like propylene glycol for skin creams or saline for injectables. A lot of companies market the compound under several names—Locorten, Flucort, Berocort, and many more—but seasoned doctors and pharmacists recognize the key ingredient in all of them. To stay in line with regulatory standards, manufacturers give clear dosing instructions, approved uses, and warnings about potential adverse effects on every label. For buyers or health professionals, it pays to read the packaging since flumethasone’s strength and recommended use can vary a lot from one product to another.
Flumethasone appears as a white crystalline powder, odorless, and stable under ordinary storage conditions. The molecule contains fluorine at position 6 and a methyl group at position 16, both features that dial up its anti-inflammatory strength. Its molecular formula reads C22H28F2O5, packing a molecular weight of 410.5 g/mol. This compound’s melting point sits around 244°C, meaning it won’t break down during typical manufacturing. It dissolves fairly well in acetone and methanol but hardly mixes with water, which drives the need for creative cream and ointment formulations to deliver the drug effectively to the skin or tissues. The strong binding at glucocorticoid receptors explains its impact on reducing swelling and immune activity, supporting broad use in medicine.
Most flumethasone products on the market go through strict quality checks for purity, residual solvents, and microbiological contamination. Regulatory authorities like the FDA or EMA keep a close eye on manufacturing lots, demanding proof of sterility for injections and safe concentrations in creams and ointments. Labels spell out the batch number, storage instructions, shelf life, strength (often 0.02% in creams or 0.5 mg per tablet), and license approvals. Hospitals and drug distributors track these numbers, making recalls or reports of side effects a possibility if anything goes off course. With each shipment, manufacturers include paperwork on analytical results and, for veterinary use, clear dosing instructions by species.
Chemists start synthesizing flumethasone using pregnenolone or similar steroidal precursors. Step by step, they chlorinate, add a double bond between carbon atoms 1 and 2, and perform selective fluorinations and methylations. Each reaction gets timed for yield and purity, with chromatography used to pick out unwanted byproducts. After the main steps, chemists might use recrystallization or precipitation to isolate flumethasone as a nearly pure solid. Large production plants design this route to run in batches, using high-pressure equipment and carefully monitored temperatures, since some reagents can turn hazardous if not managed right. Environmental regulations steer the disposal of chemical waste from these synthetic operations, keeping things as clean as possible.
Flumethasone’s structure lends itself to a handful of useful modifications. The core steroid arrangement lets chemists attach acetates to make flumethasone acetate, a more skin-friendly form seen in lots of creams. Careful hydrolysis can break off these groups, returning the drug to its base form. Under acidic or basic conditions, the compound can isomerize or break down, so all reactions happen in tightly controlled environments. Researchers sometimes change certain side chains or swap out halogen atoms to study differences in potency or side effect profile. Medical chemists keep looking for ways to adjust flumethasone and related compounds to balance inflammation-fighting power with fewer metabolic or immune impacts.
For doctors, pharmacists, and supply chain teams, flumethasone pops up under several trade names: Locorten, Flucort, Berocort, Flumethason, and many others. Its key chemical synonyms read 9α-Fluoro-16α-methylprednisolone or 6α,9α-Difluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. Each country’s drug agency may register additional local names, so it falls on practitioners to double-check ingredients before switching from one brand to another to avoid dosing mistakes or drug interactions.
Safe handling of flumethasone starts at the manufacturer and extends to pharmacies, clinics, and homes. Staff in production settings need gloves, protective coats, and ventilation to limit powder inhalation or skin contact. To prevent cross-contamination, labs and factories dedicate tools and workspaces to steroid synthesis days. Hospitals store flumethasone products under lock and key, at cool temperatures that preserve shelf life. Doctors stress minimal dosing schedules to sidestep risks like adrenal suppression, skin thinning, elevated blood sugars, and immune suppression. Both patients and veterinarians track reactions closely, reporting adverse effects to authorities for immediate action. User-safe packaging now features child-resistant caps for home use and tamper-evident seals for hospitals.
In practice, flumethasone finds its niche in severe skin diseases, allergic reactions, asthma, and autoimmune flare-ups—mostly after standard treatments run short. Dermatologists reach for it to heal stubborn eczema, psoriasis, or contact dermatitis that fails to respond to milder creams. Rheumatologists and internists sometimes rely on oral flumethasone to calm inflammation in lupus, vasculitis, or joint swelling. In veterinary offices, its role covers relief from allergic dermatitis in dogs, shock in cattle, and even as an adjunct in complicated surgical cases. Strict regulations keep the compound away from casual over-the-counter use and out of cosmetics, reflecting concerns over misuse and potential systemic absorption.
Ongoing research keeps pushing flumethasone into new territory, tracing back to questions about how synthetic glucocorticoids can treat a growing range of autoimmune and inflammatory disorders. Investigators pay close attention to its potency compared against classics like hydrocortisone or dexamethasone, searching for spots where the drug's risk–benefit balance fits better. Cross-disciplinary teams test new delivery systems, such as liposomal creams or dissolvable films, to fine-tune local effects and sidestep complications from widespread steroid exposure. On the animal front, work continues on controlled-release injections to improve compliance in veterinary medicine and limit drug residues in food animals. Academic centers and drug companies run comparative trials, sometimes even head-to-head against emerging non-steroidal anti-inflammatories.
Toxicity research on flumethasone offers a clear warning flag for overuse. Scientists have documented risks like suppression of the adrenal axis, thinning of the skin, stunted growth in children, and metabolic side effects like high blood sugar and worsened bone health. Animal studies reveal even higher risks when dosed for weeks, especially in younger or older test animals. The drug's toxicity profile led to label changes that urge the shortest effective treatment and limit use to difficult cases. Research teams now focus on understanding how genetic background, existing health problems, and even gut bacteria can shift someone’s risk of steroid complications. Newer studies leverage big data tools to scan hospital records for rare complications, all feeding into regular safety reviews.
Looking ahead, flumethasone’s place in medicine will likely keep shrinking as precision treatments, biologics, and safer topical anti-inflammatories reach the clinic. Still, flumethasone won't vanish—its unmatched power and versatility make sure of that. The compound will keep carving out a space for tough skin conditions, severe animal allergies, and situations where nothing else works. Future versions may get delivered with smart polymers, micro-encapsulation, or through new medical devices that reduce the risks of systemic exposure. Ongoing genomics projects hint that doctors will soon match patients to steroids genetically, picking the safest and most effective option up front. Medical systems, regulators, and drug makers all play a role in balancing access to this proven drug with the duty to avoid needless harm. The story of flumethasone, like many drugs in the steroid family, offers lessons in humility and ongoing vigilance.
Flumethasone belongs to a group of medicines called corticosteroids. As someone who has spent a fair bit of time in both human and animal clinics, I’ve seen Flumethasone used mostly for tackling inflammation—the type that just won’t quit. Doctors and veterinarians reach for it when milder drugs can’t cut through swelling, itching, or allergic flare-ups. What sets it apart is its strength. Flumethasone doesn’t sugarcoat things. It goes right to the trouble spot and puts out the fire.
In people, this medicine gets prescribed for some skin issues like eczema or stubborn rashes, and in tough joint problems where joints swell up, creak, and ache. The relief it offers feels real—heat and puffiness calm down, and skin stops screaming for attention. In the animal world, especially in horses and dogs, vets use Flumethasone to quiet allergies and treat breathing troubles, like heaves in horses, that make life miserable for both animal and owner.
There’s a reason Flumethasone isn’t stocked in every bathroom cabinet. Its power comes with baggage. Corticosteroids, especially the potent ones, can bring along a parade of side effects if used too much or for too long. Thin skin, weight gain, mood swings, and even slow wound healing can show up. In pets, long-term use sometimes leads to problems like thirst, frequent bathroom trips, or changes in behavior. I’ve watched folks run into trouble by treating Flumethasone like a quick fix, ignoring instructions, and ending up with more issues than what they started with.
Trust plays a huge part in using a medicine like Flumethasone. Patients and pet owners both glare at swollen joints or rashes and want them gone yesterday. But jumping right into the strongest option on the shelf skips over the risks. Medical guidance matters more than ever with corticosteroids. Every patient brings a different story—existing illnesses, other medicines they’re taking, or quirky side effects that only show up at family dinner. Doctors pay attention to these details, choosing doses, and planning how long the treatment should last.
As science advances, researchers keep searching for ways to target inflammation without so much collateral damage. While Flumethasone fills a real need right now, efforts continue to develop new medicines and strategies that leave less risk behind. A big part of the solution starts with awareness—patients, pet owners, and even some younger vets or family doctors sometimes miss how rapidly steroids can go from helpful to harmful. Education, good communication, and regular check-ins make sure this type of medicine helps more than it hurts.
Flumethasone stands as a reminder that every strong tool has its limits. Using it well takes medical guidance and paying attention to changes along the way. For many, relief from itching or breathing problems brings life back to normal, but no one walks this path alone. Every prescription, every refill, means a chance to ask questions and stay in the loop about what’s happening inside the body. That relationship—between provider and patient, or vet and pet owner—shapes how Flumethasone turns from just a chemical into a real relief for tough days.
Steroids like flumethasone hold a real place in medicine—not just in the lab but in the daily lives of people managing allergies, skin problems, or inflammatory diseases. Growing up with eczema, my mother’s regular trips to the dermatologist taught our family early about both the relief and the risks of these drugs. Flumethasone, a potent corticosteroid, often shows up as a cream or ear drop, doing heavy lifting for inflammation and itching. Relief comes fast. Yet, like with most medication, using flumethasone brings more than just the good stuff.
Doctors usually prescribe flumethasone for things that just don’t get better with mild creams—think angry red skin rashes or stubborn ear infections. No one turns to strong steroids on a whim. That’s because side effects lurk if you use too much for too long. Skin becomes thinner and easy to bruise. I’ve seen relatives develop stretch marks and even small blood vessels appearing under the skin—a simple sign the body notices every drop, even if it’s being dabbed on the surface.
On my own patch of eczema, a too-long course left my skin almost see-through. It freaked me out. That feeling drives home the need to respect limits and listen to medical advice. The balance between relief and risk never goes away with steroids.
The problems go deeper than skin. People using flumethasone near the eyes risk glaucoma or cataracts over time, so eye creams or accidental rubbing near the eyelid means keeping extra alert. Strong steroids can also sneak into the bloodstream, especially with large or broken patches of skin, opening the door to side effects throughout the body. Some folks experience mood swings, slower wound healing, or changes in the way the body manages salt and water. Even suppressed immunity might pop up, leaving a person open to more infections.
Children need extra caution—strong steroids can slow growth if absorbed systemically. So for kids and adults alike, the smallest amount for the shortest period proves safest.
Facts make all the difference. One study in the Journal of Dermatological Treatment showed noticeable skin thinning in about 10% of people using potent steroids daily for a month. Those numbers stick with me. It takes open talk between doctors and patients to spot early warning signs. No one should feel embarrassed to ask questions or double-check directions.
Sometimes people fear steroids so much that they skip treatment altogether, toughing out pain or itching that steals sleep. Better to talk about these concerns with a health provider, laying out risks and benefits together. Pharmacies can supply printed info sheets, but real understanding often comes from talking it through with someone who has walked down the steroid road before.
Respect for steroids like flumethasone means checking the amount, not overusing, and watching for changes in the skin or health. Doctors need to review every new rash or itch, and patients must keep notes on how treatments work out. When things go wrong, reporting side effects lets professionals adjust the game plan quickly.
Living with medical issues is tough enough. Safe use of flumethasone comes down to being informed, keeping honest conversations with care teams, and knowing your individual limits. The goal: more healing, less harm—step by careful step.
Flumethasone shows up in clinics and vet offices thanks to its strong anti-inflammatory nature. Doctors and vets reach for it in conditions ranging from skin troubles to asthma and joint flare-ups. Each pathway—the mouth, the vein, the muscle, the skin—brings different expectations and responsibilities. Flumethasone can be given as a tablet, injection, or topical solution, depending on what issue we are dealing with. I’ve seen how the method of delivery often makes the difference between relief and relapse, so nailing down the right one matters.
Every time someone gets a steroid, questions about risk jump to my mind. This isn’t a “try at home” kind of medication, and the method of delivery always ties back to how much of the drug actually ends up in the blood. Take the injectable version. Hospitals stick to weight-based dosing and keep emergency equipment handy because steroids in the veins make the heart race and blood sugar spike. Not every nurse feels comfortable drawing up a shot of flumethasone, either—training and practice help keep errors down.
Oral flumethasone carries a different risk profile. Swallowing those tablets dumps the drug through the digestive tract and, ultimately, the liver. Long-term oral steroids open the door to ulcers, water retention, high blood sugar, thinning bones, and mood swings. I remember patients who needed strict instructions: swallow the pill whole, never double up on a missed one, keep to the schedule. The timing of that pill matters, too. One large dose in the morning copies the body’s natural hormone rhythm, and it cuts down side effects.
Topical versions—creams or ointments—tend to stay local, but that doesn’t mean you can ignore the rules. Apply too much, or layer it on broken skin, and the steroid still slips into the blood. Some parents, wanting to bring quick relief to their kids, slather on the cream and unknowingly inch toward thinning skin, stretch marks, and even hormone disruption. In my clinic, education walks hand-in-hand with the prescription. Less is usually better, and covering the treated area with tight bandages only deepens the risks.
Setting the right dose and route needs a clear head about who’s across from you. Flumethasone in a cancer patient with low immunity brings tighter checks and possible dose reductions. Diabetics go under the microscope, since steroids block insulin. Old folks require extra care to protect their bones, especially with oral or high-dose treatment.
I’ve seen animals receive flumethasone, too. The same care applies in the vet’s office—protections for the liver, the kidneys, and regular checks for side effects keep both pets and owners safer. The idea is not about one-size-fits-all, but about listening, adjusting, and learning from past experiences.
The safest approach comes from teamwork. Doctors talk through the risks, review every medicine the patient takes, and set up check-ins to catch side effects early. Blood tests, bone scans, and honest follow-ups stop harm before it starts. Patients can help themselves, too: track changes in mood or swelling, keep questions ready for the next visit, and never share medication with others. Pharmacists often notice unsafe combinations and can flag mistakes before harm lands.
Getting flumethasone right helps more than just the patient at hand. Every correct dose, every careful check, adds a bit more trust back into healthcare. That matters to me as someone who has watched what goes wrong when people try to go it alone—this is a team effort, from the hospital up to the home.
Flumethasone doesn’t usually pop up in everyday conversations. Doctors prescribe it in tough cases—bad allergies, relentless eczema, or certain joint conditions that haven’t improved with milder treatments. This steroid packs a punch. Even in my own family, long-standing allergies led a relative to short courses of stronger corticosteroids just to get through tough patches.
There’s relief in the short term. It fights swelling and itching fast. For people stuck in cycles of flare-ups, the prospect of feeling normal, even for a few days, becomes hard to pass up. That’s how regimens can stretch from weeks to months without much thought about what staying on such a medication means for the future.
Long-term steroid use comes with a cost. Research paints a clear enough picture: extended exposure to potent corticosteroids like flumethasone leads to more than just improved symptoms. The body starts adjusting to these outside hormones. Bones thin out. Sugar levels swing out of control, and routine infections become frequent. Cushing’s syndrome, with its tell-tale round face, muscle weakness and mood swings, leaves its mark when the body’s stress hormone balance tips too far.
The Journal of Clinical Endocrinology & Metabolism notes that even low-dose, prolonged corticosteroid use puts adults at risk for osteoporosis and type 2 diabetes. Another study by the Mayo Clinic warned about increased vulnerability to infections, especially in children and the elderly. From what I’ve seen, those warnings aren’t academic. I remember a friend who wrestled with recurring skin infections after a few months of steroids—her doctor never thought long-term use would become an issue, but the cycle was hard to break.
Most medical guidelines, including those from the World Health Organization, make it clear: reserve strong steroids for short bursts, then taper off. Anyone considering flumethasone for more than a couple of weeks deserves an honest conversation with their healthcare provider about alternatives and the hidden risks. For some patients, the only way to control their symptoms is through these powerful medications—but following up on the smallest side effects, like swelling or unexplained bruises, matters. So does checking blood pressure, sugar, and bone density, especially in people older than 50.
Living with stubborn inflammation or allergies gets exhausting. But a better strategy involves more than just a prescription pad. Exploring safer treatments—like immunotherapy for allergies or physical therapy for joint pain—opens up new options for people who don’t want to add another pill or cream to their routine. Support groups and patient education, such as resources from the American Academy of Dermatology, help bridge the gap between tough symptoms and better long-term health.
In clinics, honest, direct communication hands patients a real choice. Explaining risks in clear language—instead of relying on quick fixes—makes a difference. I believe patients stay healthier when they know what’s at stake and feel supported in changing course before problems pile up. At the end of the day, the best outcomes come from a partnership: real talk, frequent check-ups, and a plan that’s bigger than just chasing symptoms.
Flumethasone fights inflammation. It’s a corticosteroid, so doctors place it in the same family as prednisone and dexamethasone. Hospitals and clinics count on meds like these to calm down angry immune reactions—skin rashes, allergies, or worse. It shows up as pills, creams, and injections. But using it during pregnancy or while breastfeeding isn’t a simple “yes” or “no” answer. Choices around medicine in these moments carry real weight because they touch two lives at once.
Based on my work in the health field, I’ve seen families puzzled by the fine print on drug labels. For flumethasone, animal studies raise some warning flags. Rats that took corticosteroids in high doses gave birth to pups with smaller bodies or bone issues. Nothing screams disaster from a mile away, but doctors stay cautious. Reliable sources like the FDA put drugs like flumethasone into a middle ground—they don’t call it totally safe for pregnant people, but they won’t call it emergency-level dangerous either.
Obstetricians play it safe and avoid corticosteroids unless there’s a real emergency: life-threatening asthma, allergy attacks, or severe skin diseases. In these cases, they’ll reach for the lowest dose for the shortest time. More isn’t always better, especially for someone with a baby on the way.
After birth, questions keep coming. Can new parents use flumethasone during breastfeeding? Most drugs slip into breast milk in some trace amount, and corticosteroids are no exception. High doses over long periods of time raise eyebrows because they could slow a baby’s growth or mess with their own natural hormone cycles. Sometimes, a short burst—a few days—won’t leave enough medicine in milk to worry about.
Mothers with skin rashes or joint pain might want relief, but pediatricians look at the bigger picture. Topical flumethasone creams rubbed onto small skin patches usually bring less risk than swallowing pills or taking injections. Still, nobody wants to rub steroid cream straight onto places a feeding baby might touch—think nipples or nearby skin—since even small doses there could land right in a baby's mouth.
Backing up these ideas, the World Health Organization and American Academy of Pediatrics have their say. Both recommend a ‘weigh the benefits and risks’ approach with any corticosteroid. Flu-like infections, poorly controlled asthma, and swelling sometimes force tough calls, and parents rely on a balance of evidence and clear advice. Prescribers who know the research don’t simply shrug; they help families figure out how much relief outweighs small but real risks.
I’ve talked with mothers over the years who felt misunderstood in the clinic. Communication often matters more than the medication itself. If someone needs anti-inflammatory treatment during pregnancy or feeds a newborn, talking openly about side effects and safer options puts power in their hands. Some decide with their doctor to switch to a steroid with a longer track record, or lean on non-drug treatments like ice packs or oatmeal baths for skin symptoms.
Doctors and pharmacists who stick to evidence—peer-reviewed studies, real patient experiences—earn trust. They help keep risks in perspective and avoid knee-jerk fears. With the right plan, most pregnant or breastfeeding people can find a way to get relief, protect their children, and stay confident through tough calls about medicine.
| Names | |
| Preferred IUPAC name | (6α,11β,16α)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| Other names |
Flumetasone
Flumethasone pivalate |
| Pronunciation | /fluːˈmiːθəˌsoʊn/ |
| Preferred IUPAC name | (6α,11β,16α)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| Other names |
Fluoromethasone
Flumetasone Flumethasone pivalate |
| Pronunciation | /fluːˈmɛθəsoʊn/ |
| Identifiers | |
| CAS Number | 2135-17-3 |
| Beilstein Reference | 4091086 |
| ChEBI | CHEBI:5128 |
| ChEMBL | CHEMBL1533 |
| ChemSpider | 15273 |
| DrugBank | DB00179 |
| ECHA InfoCard | 100,000,076 |
| EC Number | 200-960-8 |
| Gmelin Reference | 54653 |
| KEGG | D00562 |
| MeSH | D005559 |
| PubChem CID | 3352 |
| RTECS number | MD1750000 |
| UNII | Q1J190A41F |
| UN number | UN number: "UN2811 |
| CAS Number | 2135-17-3 |
| 3D model (JSmol) | `3D model (JSmol)` string for **Flumethasone**: ``` C[C@H]1C2CC(C3(C2CCC1(C3=O)F)C(F)(F)CO)OC(=O)C ``` |
| Beilstein Reference | 2793152 |
| ChEBI | CHEBI:5107 |
| ChEMBL | CHEMBL1531 |
| ChemSpider | 2845 |
| DrugBank | DB00180 |
| ECHA InfoCard | 1000407 |
| EC Number | 200-981-7 |
| Gmelin Reference | 1564705 |
| KEGG | D00579 |
| MeSH | D005563 |
| PubChem CID | 3351 |
| RTECS number | MG3150000 |
| UNII | 4R1VB8IM0F |
| UN number | UN2811 |
| Properties | |
| Chemical formula | C22H28F2O5 |
| Molar mass | 453.497 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.27 g/cm³ |
| Solubility in water | Slightly soluble in water |
| log P | 1.82 |
| Vapor pressure | 9.1E-12 mmHg |
| Acidity (pKa) | 12.53 |
| Basicity (pKb) | 1.98 |
| Magnetic susceptibility (χ) | -88.2×10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.634 |
| Dipole moment | 2.35 D |
| Chemical formula | C22H28F2O5 |
| Molar mass | 453.497 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.27 g/cm³ |
| Solubility in water | Slightly soluble |
| log P | 1.68 |
| Vapor pressure | 6.3E-12 mm Hg |
| Acidity (pKa) | 12.53 |
| Basicity (pKb) | pKb = 5.82 |
| Magnetic susceptibility (χ) | -95.2e-6 cm³/mol |
| Refractive index (nD) | 1.638 |
| Viscosity | Viscosity not reported |
| Dipole moment | 2.12 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 267.7 J·mol⁻¹·K⁻¹ |
| Std enthalpy of combustion (ΔcH⦵298) | -4812 kJ/mol |
| Std molar entropy (S⦵298) | 321.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -789.6 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -4812 kJ/mol |
| Pharmacology | |
| ATC code | **D07AB02** |
| ATC code | D07AB02 |
| Hazards | |
| Main hazards | May cause allergic skin reaction; harmful if swallowed; causes serious eye irritation |
| GHS labelling | GHS07, GHS08 |
| Pictograms | GHS06, GHS08 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. |
| Precautionary statements | P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P362+P364, P403+P233, P501 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | Flash point: 233.8°C |
| Lethal dose or concentration | LD50 (rat, oral): 1,100 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse oral 1600 mg/kg |
| NIOSH | SS1057000 |
| PEL (Permissible) | 0.005 mg/m³ |
| REL (Recommended) | 0.05 mg |
| Main hazards | May cause cancer; causes damage to organs through prolonged or repeated exposure; harmful if swallowed; may cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| GHS labelling | GHS labelling of Flumethasone: `"Warning; H361; P201; P202; P280; P308+P313; P405; P501"` |
| Pictograms | GHS06, GHS08 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | P264, P270, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P332+P313, P337+P313, P362+P364 |
| NFPA 704 (fire diamond) | NFPA 704: 2-1-0 |
| Flash point | 84.8°C |
| Autoignition temperature | Autoignition temperature: 410°C |
| Lethal dose or concentration | LD50 (mouse, oral): 2000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse oral >4000 mg/kg |
| NIOSH | MSL75640 |
| PEL (Permissible) | 0.005 mg/m³ |
| REL (Recommended) | 0.01 mg/kg |
| Related compounds | |
| Related compounds |
Dexamethasone
Betamethasone |
| Related compounds |
Betamethasone
Dexamethasone Fludrocortisone Triamcinolone |
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