Understanding Fluticasone Propionate: A Commentary

Historical Development

Years ago, people struggling with asthma and allergies often faced tough choices. Treatments like oral corticosteroids brought strong results but came with plenty of side effects. Around the late 1980s and early 1990s, researchers started looking for a solution that offered strong anti-inflammatory action without exposing the whole body to steroids. Glaxo discovered Fluticasone Propionate during this hunt for safer, targeted medications. This molecule changed the game because of its selectivity and low systemic absorption. At first, doctors worried about using corticosteroids in sprays, creams, and inhalers, but patient stories soon proved that Fluticasone delivered real relief. Regulatory approval in the 1990s set the stage for a new generation of inhaled and topical steroids—ones that could help people breathe, focus, sleep, and live more comfortably.

Product Overview

Patients and healthcare professionals usually know Fluticasone Propionate in forms such as nasal sprays, inhalers, and topical creams. Drugs like Flonase and Flovent show up on pharmacy shelves and make their way into medicine cabinets everywhere. The product stands out for its high potency. Even in tiny doses, it blocks the inflammatory signals that worsen asthma, allergic rhinitis, and some skin problems. Since its introduction, Fluticasone Propionate has been mixed with other medicines—like salmeterol—helping meet more complex disease management plans.

Physical & Chemical Properties

Fluticasone Propionate sits as a white, fine powder at room temperature. The molecule carries the formula C25H31F3O5S and weighs in at 500.6 g/mol. What sets it apart lies in the trifluoromethyl and thioester groups, both contributing to its stability and targeted action on inflamed tissues. It barely dissolves in water but mixes better with ethanol and dimethyl sulfoxide—qualities that shape how manufacturers formulate sprays and creams. Temperature swings and light exposure don’t usually bother it, helping the product last on shelves and lowering waste outside hospitals and homes.

Technical Specifications & Labeling

Manufacturers package Fluticasone Propionate according to strict standards, listing its concentration in micrograms or milligrams, depending on the delivery method. Ingredient lists include excipients such as lactose in inhalers, microcrystalline cellulose in tablets, or polyethylene glycol in topical forms. Labels warn users about recommended dosages, risks of overuse, and instructions for priming spray devices. Clear markings help doctors, pharmacists, and families avoid confusion and dosing mistakes. Regulatory bodies like the FDA check these labels and clinical data, keeping patient safety at the center of modern pharmacy practice.

Preparation Method

Chemists produce Fluticasone Propionate through multi-step synthesis. The path starts from prednisolone compounds, adding sulfur and fluorine groups to build the thioester and trifluoromethyl portions. Controlling temperature, reaction time, and chemical purity matters at every stage. The best operations use catalytic reactions and purification by chromatography, minimizing leftover solvents. Experienced chemists keep detailed records and trace all reactants—because even small impurities can influence effectiveness and safety.

Chemical Reactions & Modifications

In labs, Fluticasone Propionate goes through esterification and halogenation steps. Its thioester group resists quick breakdown, so only specific liver enzymes can deactivate it in the body. Structural tweaks to the molecule allow scientists to tailor absorption, duration, and affinity for glucocorticoid receptors. Studies focus on modifications that target tissues more precisely, with an eye toward reducing oral absorption and systemic side effects.

Synonyms & Product Names

In research and clinical practice, people call Fluticasone Propionate by several names: fluticasone 17-propionate, Cutivate, Flixotide, Flonase, Flovent, and various generic labels depending on country and manufacturer. Chemists often refer to its IUPAC name or a simplified version. For healthcare providers and patients, the commercial name usually carries more weight, given the familiarity and trust built up over years of use.

Safety & Operational Standards

Experienced operators working in pharmaceutical manufacturing plants value safety above all. Strict protocols guide chemical handling, personal protective equipment, and waste disposal. In healthcare settings, patients get coaching on pump actuation, inhaler technique, and cream application to maximize benefit and limit irritation or infection risk. Pharmacists counsel users about potential adrenal suppression and possible interactions with certain antifungals or antivirals. Ongoing monitoring, adverse event reporting systems, and real-world studies keep information up to date, allowing quick intervention if problems crop up.

Application Area

Doctors prescribe Fluticasone Propionate for asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, and eczema. Inhaled formulations help keep airways open and inflammation in check for millions struggling with daily symptoms. Nasal sprays limit sneezing, runny nose, and congestion tied to pollen, dust, or pet allergens—letting students focus in class and adults stay productive at work. Topical formulations offer relief from itching and redness linked to eczema, especially for those who can’t tolerate systemic steroids.

Research & Development

Ongoing research looks into new combinations, better delivery mechanisms, and safer long-term outcomes. Inhalers with digital counters and connected sensors promise to track adherence and outcomes more precisely. Scientists publish dozens of papers every year exploring the molecular binding profile, metabolic fate, and tissue targeting of the drug. Pediatric trials, older adult studies, and work across racial groups help fill knowledge gaps that have persisted since the drug’s early days. Drug repositioning studies and new clinical trial designs guide the next wave of respiratory and allergy care.

Toxicity Research

Studies over the past decades point to a wide margin of safety for Fluticasone Propionate, especially at normal inhaled and topical doses. Data show minimal systemic steroid effects compared to older drugs—reduced risk of growth suppression, osteoporosis, or immune suppression with proper use. Warning signs still call for attention. Inhaler misuse or overuse can lead to oral thrush or hoarseness. Rare drug-drug interactions have raised discussion among clinicians treating HIV or strong fungal infections. Families and caregivers get extra coaching to spot adverse effects early and report unusual symptoms to healthcare teams.

Future Prospects

Personalized medicine stands as an ongoing goal. In the next decade, the focus will likely rest on fine-tuning doses, improving delivery devices, and expanding access in underserved areas. Synthetic biology and advanced chemistry may create new analogues with greater tissue selectivity and even safer side effect profiles. The shift toward digital health platforms will open opportunities for remote monitoring, adherence tracking, and tailored patient support. Researchers keep asking tough questions: how best to predict which patients need added steroid protection, what long-term use means for the youngest and oldest users, and when it makes sense to rotate or combine with other therapies. Insurance coverage, pricing dynamics, and equitable access sit near the top of the agenda, as everyone deserves solutions that really work with as few tradeoffs as possible.



What is Fluticasone Propionate used for?

A Glimpse Inside the Medicine Cabinet

Most people don’t remember exactly when allergies or that stubborn stuffy nose started affecting their daily lives. I can recall family members reaching for nasal sprays each spring, searching for relief from runny noses and constant sneezing. Among these sprays, fluticasone propionate shows up frequently. It’s found on drugstore shelves under brand names like Flonase, and doctors recommend it for much more than just the seasonal sniffles.

Why Doctors Reach for Fluticasone

Fluticasone propionate belongs to the steroid family. Unlike old-fashioned allergy pills that left folks drowsy, this medicine calms swelling and irritation right where it matters—inside the nose or along the airways. Most doctors recommend it to help people manage allergic rhinitis, which means hay fever or year-round nasal allergies. By reducing inflammation, fluticasone makes it easier to breathe, sleep, and go about daily activities without feeling miserable.

It also plays a big role in managing asthma. Inhalers containing this medicine deliver measured doses directly to the lungs. This routine reduces asthma flare-ups and helps keep symptoms in check. According to the Centers for Disease Control and Prevention, nearly 25 million Americans deal with asthma, so medicines like fluticasone make a real difference in millions of lives.

Battling More Than Just Allergies

In my experience, fluticasone propionate often helps young children and older adults who just can’t shake chronic sinus congestion or pesky nasal polyps. These issues can cause fatigue and even affect how food tastes. The medicine’s anti-inflammatory action shrinks nasal lining and polyps, giving people a better shot at enjoying food and getting restful sleep.

The U.S. Food and Drug Administration has approved fluticasone for more than just allergy symptoms. People with chronic obstructive pulmonary disease (COPD) sometimes rely on inhalers that blend fluticasone with other medicines, helping them breathe more easily throughout the day. Pharmacists and researchers continuously review its benefits and side effects so that families get both relief and long-term safety.

Balancing Relief and Responsibility

Like many in my community, I have seen both the good and the bad that comes with treating long-term conditions. Overusing these sprays sometimes leads people to nosebleeds, headaches, or sore throats. Some might think a quick spray is harmless, but steroids—even at low doses—deserve a conversation with a healthcare provider.

Health experts highlight that patience pays off. Fluticasone doesn’t kick in right away. It often takes a few days before the nose clears or asthma symptoms start to fade. Sticking to a doctor’s instructions helps limit side effects and boosts the benefits. Teaching young kids or older relatives how to use inhalers or sprays correctly turns out just as important for protecting their health.

Finding Smarter Paths Forward

Pharmacists, nurses, and doctors keep searching for ways to reduce side effects and improve the delivery of medicines like fluticasone. Newer devices make dosing more reliable, and programs that teach about correct use can cut down on unnecessary risk. As more people look for ways to breathe easier, reliable information and open conversations with healthcare teams help guide the safest use of these important medicines.

What are the possible side effects of Fluticasone Propionate?

Everyday Use, Everyday Risks

Walk into any drugstore and a shelf filled with allergy and asthma treatments greets you. Fluticasone Propionate stands out, known under names like Flonase and Flovent. Doctors often trust it, patients often take it each morning, hoping for fewer sneezes or easier breaths. It’s become a household staple, but like any medication that goes into our bodies, there’s a flip side that’s too easy to gloss over.

What Happens to Our Bodies

Fluticasone Propionate works by calming down inflammation. Taken as a spray in your nose or inhaled into your lungs, it shuts off the body’s immune response in those areas. As someone who grew up with the misery of spring allergies, I remember the relief the first time I used a nasal spray with this drug. My stuffy nose cleared, my eyes stopped streaming, and I could finally focus in school. But after a few weeks, I started to notice my throat always felt scratchy. I blamed the weather. My doctor disagreed.

Common experiences for many users include local effects: a dry or irritated throat, hoarseness, or nosebleeds aren’t rare. Kids are especially sensitive to these problems. Data from large reviews suggests that nosebleeds pop up in about 10% of users taking the nasal spray. For inhaled versions, oral thrush—white patches in the mouth caused by fungal overgrowth—shows up more often than most people expect. Rinsing out your mouth and spitting after each dose lowers the risk, but who remembers every single time?

Not Just Scrapes and Sniffles

Some effects go deeper than discomfort. I remember a story from a friend on a high inhaled dose for asthma. She lost her sense of taste for weeks after starting treatment. Studies show that loss of taste or smell can linger for some, which messes with enjoying food or even detecting spoiled ingredients—important risks to keep in mind.

With long-term or high-dose use, fluticasone can sneak its way into the bloodstream, causing more serious problems. Researchers have shown that kids using high doses for months might grow a little slower, and bone thinning can become an issue as we get older. Immune defenses drop, making infections a stubborn visitor. For someone managing chronic asthma or allergies, small changes stack up over years and lead to bigger health shifts.

Facts Matter: Informed Choices and Doctor Dialogues

Recent meta-analyses summarize these risks: local side effects occur in 10–15% of users, systemic effects like adrenal suppression or slowed growth in children are rarer when used at standard doses but climb as doses increase or treatment stretches into years. Most serious reactions fade if the drug is stopped, but some, like changes in bone density, can stick around longer.

The FDA and reputable clinics suggest using the lowest effective dose and regularly checking in with your provider. Recognizing warning signs—persistent sore throat, mouth pain, repeated infections—helps catch problems early. Reviewing your technique with a healthcare professional can go a long way. Simple steps like using a spacer for inhalers or rinsing after sprays add up.

Trust, Evidence, and Small Changes

With decades of research behind fluticasone, the benefits still outweigh the risks for most people who need relief. My advice? Don’t let relief from allergies overshadow shifts in your day-to-day well-being. Stay curious, ask tough questions at appointments, and pay attention to the small signs your body gives you. That’s the only way to make sure medicine continues to work for you, and not the other way around.

How do I use Fluticasone Propionate correctly?

Why Fluticasone Propionate Matters in Everyday Life

Struggling with a stuffy nose or relentless sneezing? Many people reach for Fluticasone Propionate. It’s a go-to for treating things like allergic rhinitis or persistent sinus inflammation. Anyone who’s dealt with seasonal allergies knows the relief that comes with being able to breathe easier and sleep through the night. Fluticasone Propionate gives a lot of folks that chance to get back to their routine without reaching for tissues every hour.

Simple Steps for Using Nasal Spray

The first challenge many folks face is using the spray the right way. It sounds simple, but I’ve seen people—myself included—miss out on the benefits because of a rushed or sloppy approach. Start by giving the bottle a good shake. Blow your nose gently before using the spray. Tilt your head slightly forward. Insert the nozzle into one nostril, aiming it away from the center of your nose to avoid irritation. Press down to spray as you gently breathe in through your nose. Wipe the tip afterward, and put the cap back on. This way, the medicine hits the right spot and does its job.

Forget to prime your spray before the first use or after a week of not picking it up? You could miss your dose or end up with a weak stream. Pump it a few times into the air until you see a fine mist—otherwise, that medicated mist won’t get where it needs to go.

Consistency Pays Off

Unlike quick-fix nasal decongestants, Fluticasone Propionate works best with regular use. You might not notice big changes the first day. People sometimes stop using it too soon, hoping for instant relief. Research shows that most users feel significant improvement after several days of steady dosing. Stopping and starting creates more frustration and wasted medication than just building it up in your routine.

Common Stumble Blocks and Solutions

A lot of folks hesitate because of worries about side effects. Nosebleeds, dryness, and minor irritation come up, especially if the spray hits the delicate middle wall of the nose. Angling the nozzle outward and not overusing the product helps here. Doctors recommend keeping the dose as low as needed for relief, which reduces the risk of those problems.

Another worry comes from people with underlying conditions or those already taking other medications. Fluticasone Propionate generally handles allergies and inflammation locally, working right at the site, which keeps systemic side effects low. The American Academy of Allergy, Asthma & Immunology supports its safety profile, especially compared to long-term oral steroid use. Even so, a quick chat with a healthcare provider helps clear up any questions, especially for people managing several prescriptions.

Keeping It Safe

Kids need extra care with nasal sprays. Parents need to follow the dosing instructions carefully. Some doctors suggest involving kids in the routine and giving them control as they get older, which encourages better adherence and teaches good habits early on.

Regular cleaning of the spray tip matters more than people think. I once had a bottle get clogged. Skipping maintenance just adds hassle later. A little warm water on the tip once a week and wiping down after use go a long way.

Living with Allergies Doesn’t Have to Run Your Life

Allergies can make simple tasks miserable, but effective tools like Fluticasone Propionate, when used the right way, bring huge relief. Using the spray as part of a daily routine and paying attention to technique helps the body recover and return to activities people actually enjoy. For persistent symptoms, talking with a doctor keeps things manageable and can open the door to other treatments or lifestyle tweaks.

Is Fluticasone Propionate safe for long-term use?

Understanding Fluticasone in Everyday Life

Fluticasone propionate sits on the shelves of just about every pharmacy. Folks dealing with asthma, allergies, or chronic nasal problems recognize its name. Doctors hand out prescriptions for it in sprays or inhalers, promising fewer flare-ups and relief from stuffy noses and wheezing. Many ask if this little bottle of relief can become a long-term fix without sneaking in nasty surprises.

Putting Trust in What Doctors Know

Doctors have over twenty years of research and practice under their belts with this medicine. Unlike some newer drugs, fluticasone’s side effects don't hide out of plain sight. Studies that track folks for years say that very small amounts of this steroid, sprayed into the nose or breathing tubes, stay right where they’re put. Hardly any makes its way into the bloodstream. For most adults and children—especially those who follow their doctor’s instructions—a standard dose doesn’t harm the body’s balance of hormones or bone strength.

Looking Closer at the Risks

Every medicine brings risks, and steroids boost certain odds—thinner skin, nosebleeds, and even rare throat infections. Some people, especially kids, worry about growth concerns. Pediatric doctors rely on the facts, and those point to rare, slight delays in height gain. In practice, most children catch up when doses stay low, and symptoms stay controlled.

Fluticasone noses into the bloodstream less than old-school oral steroids. That fact reduces trouble with bone thinning, blood sugar jumps, or weight gain. Eye pressure can drift upward for a small group, since steroids sometimes poke at the pathways that drain fluid. Regular check-ups tease out these issues before they root themselves into bigger problems.

In my own family, my child needed inhaled steroids for years. We checked in with her doctor every six months, kept doses at the minimum needed, and tracked her growth closely. She managed her asthma, played sports, and hit a growth spurt right on target—proof, at least in our case, that caution and routine supervision offer good peace of mind.

Seeking Solutions to Common Concerns

No pill or spray works magic without responsibility. Patients should talk with their doctors about why and how long they plan to use fluticasone. Starting at the smallest effective dose and stepping down when allergies calm or asthma behaves makes a huge difference. Doctors sometimes recommend “drug holidays” if symptoms fade with time.

Regular follow-ups matter—especially for children and older adults. Screening can catch any hint of slowing growth, changes in vision, or voice hoarseness. If nosebleeds or soreness crop up, switching the delivery device or teaching better spraying technique helps. For those on high doses or mixing medicine types, bloodwork or a bone scan can answer lingering questions about safety.

Access to ongoing information really helps. Reliable health websites, trusted pharmacists, and support groups make space for second opinions or encouragement. The more folks know, the easier it gets to spot side effects before they disrupt life.

Balancing Relief and Responsibility

Anyone thinking about using fluticasone propionate for months on end faces a choice: Find the relief they need, but keep an honest watch on the body’s signals. Medicine works best with a mix of personal attention, routine supervision, and a doctor who listens. The goal—relief without regret—rests on that healthy partnership.

Can Fluticasone Propionate be used together with other medications?

Common Concerns About Combining Medications

Anyone juggling allergies, asthma, or other breathing issues probably recognizes Fluticasone Propionate. This steroid helps control inflammation inside nasal passages and airways. Life rarely sticks to one diagnosis, so questions pop up about taking Fluticasone alongside other pills or sprays.

Why Drug Combinations Raise Eyebrows

Every person metabolizes medicine a bit differently, and side effects rarely follow a cookbook formula. With modern medicine offering a buffet of choices, combining medicines sounds simple, but the body treats each new compound like a guest at a party. Each drug can influence how another works. Fluticasone belongs to a family of medications—corticosteroids—known for quieting down the immune system. That means adding new medicines needs careful attention.

What Science Says About Fluticasone and Drug Mixing

Most patients use Fluticasone nasal sprays to curb hay fever or breathe clearer. People with asthma manage their symptoms using inhaled versions. Both types work by calming inflammation. Research from the American Academy of Allergy, Asthma, and Immunology points out that Fluticasone usually plays well with allergy antihistamines like Loratadine or Cetirizine. Doctors often prescribe them together. The combo cuts down on sneezing and stuffy noses without wiping out energy or messing with blood pressure.

Problems show up more with certain antifungal and HIV medications. Medications such as ketoconazole and ritonavir block the liver enzymes that break down Fluticasone. This can make steroid levels spike, opening the door to more serious side effects: fragile skin, weight gain, and trouble fighting infections. Taking Fluticasone with other corticosteroids, whether for arthritis or eczema, also increases overall steroid exposure. That can weaken bones or invite adrenal complications if a person isn’t careful.

What Experience Teaches: Talking to Your Doctor

Personal experience matters just as much as scientific studies. For many, adding new medications brings out old worries—dizziness, unusual bruising, or just feeling “off.” It surprises people when common over-the-counter drugs like ibuprofen don’t mix easily with every prescription. Regular check-ins with healthcare providers catch interactions early. They spot trouble signs and keep routines in check.

Don’t forget about herbal supplements or wellness products. Garlic pills, St. John’s Wort, or even certain teas change how steroids work for some people. Drug interaction databases rarely capture every home remedy or supplement, so a thorough medication list helps health professionals do their job.

Smart Strategies for Managing Multiple Medications

Juggling prescriptions works best with open communication. Bring every bottle—prescribed or bought—during checkups. Pharmacists can often spot risky combinations right away, saving time and worry. Setting up pill organizers and reminders on phones makes sticking to complex schedules less stressful. Tracking flare-ups or side effects in a journal provides solid information to share with doctors, making each visit more productive.

The real goal isn’t just avoiding problems—it's a day with fewer symptoms and more certainty about what’s working. Fluticasone can usually fit into that plan, as long as every player at the table is accounted for.

Fluticasone Propionate
Names
Preferred IUPAC name S-(fluoromethyl) 6α,9-difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioate 17-propionate
Other names Flixonase
Flovent
Flonase
Flixotide
Pronunciation /fluːˈtɪk.ə.səʊn ˌprəʊ.piˈəʊ.neɪt/
Preferred IUPAC name S-fluoromethyl 6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyloxyandrosta-1,4-diene-17β-carbothioate
Other names Flixotide
Flonase
Cutivate
Flovent
Veramyst
Flixonase
Pronunciation /fluːˈtɪk.ə.səʊn prəˈpɒp.i.eɪt/
Identifiers
CAS Number 80474-14-2
Beilstein Reference 3526503
ChEBI CHEBI:5075
ChEMBL CHEMBL1236
ChemSpider 12857402
DrugBank DB02774
ECHA InfoCard 100.120.819
EC Number EC 606-674-2
Gmelin Reference 681601
KEGG D01106
MeSH D017693
PubChem CID 444036
RTECS number WF6JXR16TS
UNII XSF9T6Y6WC
UN number UN number not assigned
CAS Number 80474-14-2
3D model (JSmol) `3D model (JSmol)` string for Fluticasone Propionate: ``` C(C1=CC(=C(C(=C1)F)F)C2C(C(C(O2)COC(=O)C3=CC=CC=C3Cl)O)O)(=O)C(F)(F)F ``` This is the **SMILES string** that can be used in JSmol or other molecular viewers to generate a 3D model.
Beilstein Reference 3566654
ChEBI CHEBI:50716
ChEMBL CHEMBL1239
ChemSpider 60859
DrugBank DB02774
ECHA InfoCard 12eea4ea-5b40-42bb-be10-02d6bc9b5b6b
EC Number EC 219-017-9
Gmelin Reference 85843
KEGG D01136
MeSH D015283
PubChem CID 444036
RTECS number RS8267500
UNII XN5DWQH8Q4
UN number UN number does not exist
CompTox Dashboard (EPA) DTXSID6020162
Properties
Chemical formula C25H31F3O5S
Molar mass 500.57 g/mol
Appearance white to off-white powder
Odor Odorless
Density 1.33 g/cm³
Solubility in water Practically insoluble in water
log P 2.7
Vapor pressure 6.6 × 10⁻⁹ mm Hg at 25°C
Acidity (pKa) 12.75
Basicity (pKb) 2.7
Magnetic susceptibility (χ) -1.0e-6
Refractive index (nD) 1.610
Dipole moment 2.45 D
Chemical formula C25H31F3O5S
Molar mass 500.57 g/mol
Appearance white to off-white powder
Odor Odorless
Density 1.19 g/cm³
Solubility in water Practically insoluble in water
log P 2.7
Vapor pressure 3.8 x 10^-9 mmHg
Acidity (pKa) 2.8
Basicity (pKb) 2.7
Magnetic susceptibility (χ) -2.2e-6
Refractive index (nD) 1.589
Dipole moment 2.56 D
Thermochemistry
Std molar entropy (S⦵298) Std molar entropy (S⦵298) of Fluticasone Propionate is 675.2 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -1619 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -7548 kJ/mol
Std enthalpy of formation (ΔfH⦵298) -1488.8 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -7468 kJ/mol
Pharmacology
ATC code R01AD08
ATC code R01AD08
Hazards
Main hazards May cause allergic reactions, immunosuppression, adrenal suppression, growth retardation in children, and increased risk of infections.
GHS labelling GHS07, GHS08
Pictograms GHS07, GHS08
Signal word No signal word
Hazard statements No hazard statements.
Precautionary statements Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. For intranasal use only. Avoid spraying in eyes. Use only as directed by your doctor.
Flash point > 444.6 °C
Lethal dose or concentration Rat oral LD₅₀: >2,000 mg/kg
LD50 (median dose) > > 1000 mg/kg (rat, oral)
NIOSH Not Listed
PEL (Permissible) PEL (Permissible) for Fluticasone Propionate: Not established
REL (Recommended) 50–100 micrograms twice daily
IDLH (Immediate danger) Not listed
Main hazards May cause allergic reactions, immunosuppression, adrenal suppression, glaucoma, cataracts, and growth suppression in children.
GHS labelling GHS07, GHS08
Pictograms GHS02, GHS07, GHS08
Signal word No signal word
Hazard statements No hazard statements.
Precautionary statements Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Use only as directed. Avoid contact with eyes. If irritation develops, discontinue use and consult a physician.
Flash point > 442.1 °C
Lethal dose or concentration LD₅₀ (rat, oral): >1000 mg/kg
LD50 (median dose) > 1000 mg/kg (rat, oral)
PEL (Permissible) Not Established
REL (Recommended) 50-100 micrograms once daily
IDLH (Immediate danger) Not established
Related compounds
Related compounds Fluticasone
Fluticasone furoate
Dexamethasone
Betamethasone
Beclometasone dipropionate
Mometasone furoate
Hydrocortisone
Prednisolone
Related compounds Fluticasone
Fluticasone furoate
Flunisolide
Mometasone furoate
Budesonide
Beclometasone dipropionate
Triamcinolone acetonide