Hydrocortisone didn’t appear overnight. Its roots start in the early 20th century, by way of scientists who saw the human body struggling against inflammation and got curious about how the adrenal glands seemed to help. Work by Edward Kendall, Tadeus Reichstein, and Philip Hench pushed the field forward in the 1930s and 1940s. Their experiments isolated compounds from adrenal cortex tissue, and eventually they pulled out cortisone and hydrocortisone. The pace quickened once doctors saw patients with rheumatoid arthritis and Addison’s disease responding to these new steroids, giving these scientists a Nobel Prize in 1950. Pharmaceutical companies raced to make production feasible, shifting the world away from animal-derived material and toward chemical synthesis. So in the decades that followed, hydrocortisone became more than a miracle cure. It grew into a staple of both prescription medicine cabinets and standard laboratory work.
Hydrocortisone often shows up as a white or nearly white, odorless powder. In the pharmacy, it gets packed into creams, lotions, tablets, syrups, injectable solutions, and even eye drops. People struggling with eczema or an allergic rash might reach for a tub of hydrocortisone cream. Hospitals keep vials of injectables ready for emergencies like adrenal crisis. Oral tablets play a crucial role in hormone replacement for people who can’t produce their own corticosteroids. Each product hits the market with strict concentration demands, sometimes a half percent in a topical cream, sometimes dozens of milligrams per tablet for replacement therapy.
Hydrocortisone’s molecular structure packs a punch: C21H30O5. These steroid molecules aren’t large by genetic standards, but their architecture makes them biologically active at vanishingly low concentrations. Melting point hovers around 215°C. It’s practically insoluble in water—special solvents step in for injections and creams. Chemical stability stays reliable under normal storage but hydrocortisone can lose potency if exposed to excessive light, moisture, or high temperatures. This means pharmacists and manufacturers watch storage conditions closely.
Every tube, vial, or blister pack carries clear, tightly-regulated labels. Expect to read hydrocortisone’s active ingredient content, full list of excipients, batch number, and expiry date. U.S. Pharmacopeia and European Pharmacopoeia standards steer much of this, covering particle size, purity levels, and the permissible limits for related impurities. Tablets show precise milligram amounts. Creams and ointments reveal percentage strength. Technical standards demand not just the display of active content but a host of measurements for mechanical quality, microbial purity, and packaging integrity.
Building hydrocortisone used to start with animal glands. Modern-day preparation usually goes through a semi-synthetic route using plant steroids as raw starter material—diosgenin from wild yams or solasodine from potatoes. The process turns plant steroid cores into hydrocortisone by tweaking side chains, oxidizing certain positions, and reducing others. Enzymes and chemical catalysts speed things along. Pharmaceutical plants rely on reactor vessels and vacuum filtration to isolate and refine the compound. Quality control specialists step in each step to make sure no contaminants sneak into the final batch. The journey from raw material to final product can cover dozens of chemical reactions, sometimes requiring specialized knowledge just to keep the reactions from running out of control.
Chemists have built a toolbox of reactions for hydrocortisone over the years. Popular modifications target the molecule’s C-17 and C-21 positions, both susceptible to changes that alter activity and solubility. The addition of acetate, sodium succinate, or sodium phosphate groups allows better absorption or longer shelf life. These derivatives enter the market for their particular medical strengths: sodium succinate for rapid injection in emergencies; acetate for extended action in topical use. Hydrogenation, oxidation, and esterification create analogs and prodrugs, each tailored for speed or strength in the body.
Hydrocortisone comes with a long list of aliases. Pharmaceutical labels sometimes print “cortisol,” its natural biological name. Prescriptions or ingredient lists may mention 11β,17α,21-trihydroxy-pregn-4-ene-3,20-dione. Brands vary from Solu-Cortef and Cortef to generics. Hospitals and regulatory documents might include international CAS numbers (50-23-7) or EINECS numbers (200-020-1). Checking all the synonyms can help doctors, scientists, and patients avoid mix-ups, especially between similar-sounding steroids.
Hydrocortisone’s benefits depend on handling and dosing it with respect for its power. Pharmacies and hospitals treat storage like a science—room temperature, dry conditions, original packaging. Topical creams avoid eyes and open wounds. Oral and injectable forms only go to those who truly need them; long-term misuse can thin skin, raise blood sugar, weaken bones, or suppress the immune response. Occupational safety guidelines call for gloves and eye protection in manufacturing settings. Medical prescribers and their patients follow up to track blood pressure, blood sugar, and infection risk. Bulk powder and liquid forms get labeled with hazard warnings, emphasizing the need for responsible handling from factory floor to bedside.
Doctors count on hydrocortisone for a long list of conditions. Anything linked to inflammation signals its potential—dermatitis, allergic reactions, asthma, lupus, inflammatory bowel disease, or Addison’s disease. Intensive care doctors bring out intravenous hydrocortisone for septic shock or adrenal crisis. Endocrinologists may prescribe daily pills to replace what the adrenal glands no longer make. Skin specialists reach for hydrocortisone topicals to calm rashes, bug bites, and patchy skin outbreaks. Even optometrists may use it after eye surgery to cool post-operative swelling. Its flexibility in formulation ensures a place in almost every hospital or rural clinic.
Scientific journals continue to publish work on hydrocortisone, its mechanism, and its best uses. Recent years saw a burst of investigation into not just how the drug works, but also how to avoid side effects. Clinical studies look at new forms—perhaps a slow-release patch or a targeted nanoparticle cream. Researchers in endocrinology dig into better hormone replacement schedules, trying to match the body’s natural daily rhythm, instead of a blunt, once-a-day pill. Teams in dermatology compare hydrocortisone with newer biologic treatments, seeing if old-school steroids still have a place beside the latest drugs. Sophisticated analytical tools—HPLC, mass spectrometry—let labs pick apart even the faintest impurities, raising safety standards along the way.
Long-term reliance on hydrocortisone highlights its power—and its risks. Toxicity studies keep shining a light on subtle danger signals: atrophy in the skin after months of overuse, osteoporosis and diabetes from too much systemic exposure, and a suppressed stress response that leaves users vulnerable during illness if their drug is stopped suddenly. Animal research checks both acute and chronic dosing, looking for thresholds where long-term harm begins. Human studies track kids on long-term asthma therapy to spot slowed growth or weaker immunity. Responsible use means not only careful dosing, but solid patient education. Doctors, pharmacists, and patients all carry the responsibility to respect hydrocortisone’s benefits while being alert to the real, evidence-backed risks.
All the work that’s gone into hydrocortisone, and all its successes, don’t close the door on newer approaches. Drug developers aim for smarter delivery: creams that reach only the right skin layer and not the bloodstream, tablets that mimic minute-by-minute hormone swings, emergency injectors with fewer side effects, and compounds that hush only the bad inflammation while protecting the body’s repair signals. Personalized medicine stands on the horizon, with genetic tests suggesting whether one person’s immune system or metabolism needs a tweak to a standard dosing plan. Research into the microbiome, diet, and lifestyle partners with clinical trials to point toward safer, more effective steroid use. With all this progress, one thing stays constant—patients need reliable, evidence-tested drugs, and the scientific community keeps building on a shared foundation of hard evidence, careful safety monitoring, and an honest look at both strengths and pitfalls.
Hydrocortisone finds a home in most first aid kits and bathroom drawers for a simple reason: it works to calm down irritation and swelling. From itchy mosquito bites to stubborn rashes, I’ve reached for this cream plenty of times, especially during summer camping trips or after brushing up against poison ivy. Whether in a pharmacy or a family home, its practical value can’t be missed.
Hydrocortisone acts as a corticosteroid, one of a group of hormones our bodies already use to manage stress and inflammation. When placed on red, inflamed skin, it dials down the overactive response that leads to itching, swelling, and redness. The American Academy of Dermatology points out that mild hydrocortisone creams work well for eczema flare-ups, allergic reactions, or mild dermatitis.
Doctors and pharmacists have leaned on this medicine since the 1950s, which helps build trust in its safety profile—at least for short-term use on limited skin areas. Prescription versions treat more severe forms of inflammation, like ulcerative colitis and adrenal insufficiency, although those usually require close medical supervision. Most folks just use the over-the-counter version for common rashes or bug bites.
Parents often use hydrocortisone on kids for diaper rash caused by allergies or eczema. I remember as a child, anything with hives or redness would send my mom searching for that familiar tube. It’s not only for kids, though. Grownups with psoriasis, allergies, or bad sunburns benefit from its soothing touch.
Still, it’s smart to see a doctor for rashes that look infected or don’t clear up after about a week. Hydrocortisone might mask signs of bacterial or fungal infection, so dragging out use for weeks on end makes things worse. The Mayo Clinic often reminds patients not to overdo it, especially on broken or thin skin and not to cover treated spots with airtight dressings.
No medicine comes without risks. Using hydrocortisone on sensitive places like the face or underarms, or for extended stretches, can cause skin thinning or streaks. Some people turn to stronger versions or use them too frequently, thinking more must be better, but this approach only triggers side effects.
Here’s a fact: regular handwashing and moisture control do more for eczema and itch than piling on extra cream. Less is often more. Hydrocortisone also doesn’t tackle fungal or viral skin problems, so for ringworm or cold sores, other treatments are needed. Pharmacists and family doctors stay on alert for these issues, educating folks on correct usage.
The best approach comes down to moderation and good advice. Read directions on every package, and ask a professional if questions come up. American pharmacists are a huge resource for practical advice—never hesitate to get their input about safe application or alternatives.
Keeping hydrocortisone on hand proves its worth time and again, calming uncomfortable skin and restoring peace in households. As with any medicine, listening to your body and getting timely help from medical professionals ensures it stays effective and safe.
Hydrocortisone cream helps calm itchy, irritated, and inflamed skin. Many folks pick it up at a pharmacy for rashes, bug bites, or minor eczema flare-ups. As someone who deals with the occasional poison ivy attack, I’ve seen how a pea-sized amount soothes redness in under half an hour. Overusing the cream gets people in trouble, so treating it like some sort of cure-all won’t help anyone in the long run. Skin isn’t just a surface; it’s the body’s first defense, and plastering too much on causes thinning and other troubles.
Wash your hands. A lot of directions miss this step, but it matters. Any bacteria or dirt stays on your hands moves right onto skin you’re trying to treat. After drying your hands, squeeze a small dab of cream onto your finger. Rubbing on a thick layer wastes the product and can lead to more side effects. Thin layers soak in, doing the job without blocking pores.
Gently dab the cream on the affected area. Rubbing too hard just makes things worse, by irritating angry skin even more. Cover the area lightly, then wash your hands again. Hydrocortisone should never end up near your mouth or eyes, so this extra handwash cuts the risk. If a healthcare provider tells you to cover the spot with a bandage, go for it, but usually letting skin breathe helps just as much.
Hydrocortisone isn’t meant for open wounds or broken skin. Sticking to the label’s directions, or asking a pharmacist, helps users avoid problems. Most doctors recommend once or twice a day for no longer than a week at a time. Kids are extra sensitive to ingredients, so smaller doses and shorter timeframes make more sense for them.
People trust non-prescription medicines, but there’s still a risk in ignoring instructions. Overusing steroids like hydrocortisone causes skin thinning, strange markings, and even worsened rashes. The FDA warns people about long-term use, but some folks don’t notice damage right away. I’ve seen neighbors treat every itch the same and end up with weaker skin over the years.
If you see no improvement after a week, or the redness spreads, it’s time to see someone qualified. Doctors check for underlying infections or allergies that look like garden-variety rashes but need different treatments. Kids, pregnant women, or those with chronic illness should always double-check with a clinician before starting creams.
Mayo Clinic and the American Academy of Dermatology consistently recommend minimal use for steroid creams. Studies show that short, targeted use reduces itching and heals most mild skin problems faster than untreated rashes. For chronic issues like eczema, building a plan with a dermatologist prevents misuse and protects skin health over time.
Applying hydrocortisone the right way isn’t complicated. It takes attention to clean hands, thin layers, and a preference for safety over speed. With so many folks reaching for these tubes each year, those small steps deliver better results, fewer side effects, and resilient skin for the long haul.
Hydrocortisone gets used for lots of things—from easing red itchy skin rashes to keeping inflammation in check for people with chronic illnesses. The drug mimics your own stress hormone, cortisol. Doctors have relied on it for decades, especially for skin issues, allergies, and certain autoimmune problems. Since hydrocortisone comes in pills, creams, and injections, the way it’s taken affects its risks.
A dab of hydrocortisone cream for a bug bite every so often probably won’t cause trouble. Still, I’ve seen folks land in uncomfortable situations—folks have told me about burning or stinging after putting cream on broken or sensitive skin. Shaped by my own family’s run-ins with eczema, I’ve watched kids scratching even more after a fresh application, especially when the skin is open. Other common issues include thinning skin, weird stretch marks and tiny blood vessels showing up like little roadmaps under the skin. Any medicine you rub on can sometimes trigger local reactions, even hives.
Taking hydrocortisone by mouth, or for weeks at a stretch, brings stronger risks. Folks with autoimmune disease often need daily doses that keep symptoms under control. Over time, though, the medicine can flip the script and cause big problems. Bones may thin out. Older adults, especially women, face a higher chance of fractures. Muscle weakness can grow, and even young, healthy people can find themselves feeling puffy and tired, or suddenly gaining unexplained pounds. Daily pills stress out the body’s natural hormone system—eventually, the adrenal glands get lazy and stop making enough cortisol on their own.
Someone taking hydrocortisone long-term can find their blood sugar creeping up, even if they’ve never had diabetes. Routines like early morning blood tests become a part of life. High blood pressure and mood swings are common—friends and family often comment on irritability and changes in behavior. Small cuts get infected more easily. As a parent, I watched my own kid’s common cold stretch on twice as long after starting corticosteroids. Even a little sniffle caused worry, since hydrocortisone stops the immune system from working at full speed.
Doctors need to spell out the risks instead of rushing to prescribe. People should actually hear what stopping hydrocortisone suddenly can do—withdrawal shakes, nausea and dangerous changes in blood pressure shouldn’t come as a surprise. Pharmacists belong in the conversation too. They’re often first to catch mistakes or red flags, especially if someone’s getting too much or mixing with other drugs like NSAIDs that can irritate the stomach lining.
There’s no clean, one-size-fits-all answer for making hydrocortisone safer. Topical use, limited to a week or two, helps minimize problems, especially for kids. Using the lowest possible dose for the shortest time works best. Bone scans for folks needing long-term therapy, steady check-ins for blood sugar, and honest talks about mental health all help balance the drug’s powerful benefits with its real risks. Regular follow-ups give room to make changes before trouble starts piling up.
Red, itchy skin rashes drive people to look for quick relief. Hydrocortisone cream sits on pharmacy shelves, promising comfort. It's labeled as “mild” and “gentle,” so it’s easy to assume it works for almost any skin trouble — even on the face or delicate skin of children. But easy access and gentle branding can sometimes hide important cautions.
Facial skin acts much more sensitive than other parts of the body. It takes just a bit of irritation or the wrong skincare routine to spark redness or flaking. Steroid creams like hydrocortisone can sometimes provide fast relief, but there are risks with using them on the face. Long-term or frequent use on delicate areas brings the potential for thinning skin, rosacea-like flare-ups, or even small blood vessels showing up under the surface. Some folks might get hooked on that temporary calm, putting it on day after day, but the side effects build quietly.
Kids’ skin acts thinner, absorbs creams more easily, and shows reactions faster than adults. Every parent juggling diaper rashes, insect bites, or eczema patches has stared at the cream tube, wondering what’s truly safe. Doctors often recommend the lowest strength — usually the 1% version — and only for a short time. Even then, open wounds or broken skin could let more medicine get through than anyone wants. Problems can sneak up: lighter marks, bruising, delayed healing, or hormone side effects from regular exposure. Most parents aren’t told these details at checkout, and sometimes even pharmacists will shrug and say, “It’s just a mild steroid.” Yet nothing about a baby’s face or hands feels ordinary.
Stories and tips only go so far, so it’s smart to look at what the science shows. Studies in respected dermatology journals warn about using topical steroids freely, especially on infants and toddlers. Even one package insert for hydrocortisone tells users to avoid the eyes, mouth, and broken skin — not because it’s dangerous for everyone, but because problems appear faster in certain spots. The American Academy of Dermatology specifically points out the risks of prolonged or unsupervised steroid use, noting a pattern of side effects when parents skip medical advice.
Simple steps at home bring most skin flare-ups under control without jumping straight to hydrocortisone. Gentle cleansing, fragrance-free moisturizers, and protection from harsh weather help the skin do its job. For trouble spots that refuse to clear up, getting professional input makes sense. Sometimes doctors suggest medicine for a few days, then switch to non-steroid creams or help families sort out underlying causes like allergies or irritants.
Families value quick fixes but usually want long-term answers, too. Taking a few minutes to ask questions, reading the label, and stepping back from automatic creams can spare trouble later. The best medical advice weighs the risks, listens to concerns, and outlines step-by-step care that fits each person — not just the average rash.
For anyone who’s dealt with a fiery bug bite, mystery rash, or a patch of eczema that flares at the worst time, the word “hydrocortisone” probably rings some bells. Probably, there’s a tube of it somewhere in the medicine cabinet at home. This cream, often sold in one percent strength, is famous for quieting the itch and calming red, angry skin. But people still get caught up on the same question—do you need a doctor to hand you a prescription before buying some?
People pick up one-percent hydrocortisone over the counter at pharmacies, corner stores, and big box shops. There’s no need to schedule an appointment just to soothe an itchy patch on the arm or a mosquito attack on vacation. The U.S. Food and Drug Administration (FDA) gave the green light for low-dose hydrocortisone to be sold directly to the public. Studies show that using one percent hydrocortisone for a short period causes few problems when the skin just needs a quick fix.
Doctors reach for stronger hydrocortisone—formulations of 2.5% or more—when the rash refuses to budge, or there’s a more stubborn flare-up like severe eczema or psoriasis. Those creams sit behind the pharmacy counter and come out with a prescription. This makes sense, since stronger steroids can thin the skin, trigger infections, and cause side effects if used the wrong way. A healthcare provider looks at the rash, asks questions, and figures out if a strong steroid even makes sense for what’s going on. Sometimes, itching masks an infection or something more serious.
The gap between a quick pharmacy run and needing a prescription points to something deeper—many people skip seeing a healthcare professional for things they think are low stakes. Sometimes the patch gets better fast. Other folks keep piling on over-the-counter creams and, weeks later, land at the doctor’s office with thinning, fragile skin or a worse rash than they started with. Young children, folks with immune conditions, or anyone with a weird spread of symptoms should get extra caution. I’ve heard stories from friends who thought they could “tough it out” with some cream, only to end up in urgent care because the rash took a wrong turn.
Educating people about the right reason to use hydrocortisone goes further than any marketing pamphlet. Most pharmacists offer fast advice. Walking up to the counter and asking if over-the-counter strength is enough often clears up confusion. Better health literacy helps people spot those moments when a simple home fix won’t do the trick. Insurance and cost matter too—seeing a doctor isn’t cheap for everyone. These barriers shouldn’t stop people from knowing when to step up care.
Using hydrocortisone with common sense can make all the difference. If that patch returns again and again, covers a big chunk of skin, or shows signs like oozing or pain, those are clear signals for a check-in with a professional. Also, limit use to about a week unless told otherwise. Respecting those red flags saves a lot of trouble later on. It’s always better to ask and get the right advice than guess, hoping for the best. Pharmacies, clinics, and telehealth services have a big role in keeping skin healthy and people out of unnecessary trouble.
| Names | |
| Preferred IUPAC name | (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione |
| Other names |
Cortisol
Hydrocortone Solu-Cortef Cortef |
| Pronunciation | /ˌhaɪ.drəˈkɔːr.tɪˌzoʊn/ |
| Preferred IUPAC name | (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione |
| Other names |
Cortisol
Hydrocortone Cortef Solu-Cortef |
| Pronunciation | /ˌhaɪdrəˈkɔːrtɪsoʊn/ |
| Identifiers | |
| CAS Number | 50-23-7 |
| Beilstein Reference | 3570818 |
| ChEBI | CHEBI:17650 |
| ChEMBL | CHEMBL418 |
| ChemSpider | 5755 |
| DrugBank | DB00741 |
| ECHA InfoCard | 03d3e5e038b5-47da-b7ee-815f152d2eb2 |
| EC Number | 200-020-1 |
| Gmelin Reference | 8715 |
| KEGG | C02134 |
| MeSH | D006805 |
| PubChem CID | 5754 |
| RTECS number | WI1750000 |
| UNII | YOK3PU4FGP |
| UN number | UN2811 |
| CAS Number | 50-23-7 |
| Beilstein Reference | 2468 |
| ChEBI | CHEBI:17650 |
| ChEMBL | CHEMBL: CHEMBL418 |
| ChemSpider | 5754 |
| DrugBank | DB00741 |
| ECHA InfoCard | 100.032. |
| EC Number | 200-020-1 |
| Gmelin Reference | 5666 |
| KEGG | D00068 |
| MeSH | D006957 |
| PubChem CID | 5754 |
| RTECS number | MG1050000 |
| UNII | WI4X0X7BPJ |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID7036872 |
| Properties | |
| Chemical formula | C21H30O5 |
| Molar mass | 362.47 g/mol |
| Appearance | White or almost white, crystalline powder |
| Odor | odorless |
| Density | 0.43 g/cm3 |
| Solubility in water | Slightly soluble in water |
| log P | 1.61 |
| Acidity (pKa) | 12.59 |
| Basicity (pKb) | 12.53 |
| Magnetic susceptibility (χ) | -9.2e-6 |
| Refractive index (nD) | 1.61 |
| Dipole moment | 1.69 D |
| Chemical formula | C21H30O5 |
| Molar mass | 362.466 g/mol |
| Appearance | White to almost white, crystalline powder. |
| Odor | Odorless |
| Density | 1.0 g/cm3 |
| Solubility in water | Slightly soluble |
| log P | 1.61 |
| Vapor pressure | Negligible |
| Acidity (pKa) | 12.59 |
| Basicity (pKb) | 12.53 |
| Magnetic susceptibility (χ) | -9.2e-6 |
| Refractive index (nD) | 1.615 |
| Dipole moment | Dipole moment of Hydrocortisone: 4.58 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 334.8 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -604.6 kJ·mol⁻¹ |
| Std enthalpy of combustion (ΔcH⦵298) | -7441 kJ/mol |
| Std molar entropy (S⦵298) | 319.0 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -596.86 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -5409 kJ/mol |
| Pharmacology | |
| ATC code | H02AB09 |
| ATC code | H02AB09 |
| Hazards | |
| Main hazards | May cause eye irritation, skin irritation, allergic reactions, and may suppress immune response with prolonged use. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | eye", "pregnancy", "prescription", "kidney", "caution |
| Signal word | Warning |
| Hazard statements | No hazard statements. |
| Precautionary statements | Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin unless directed by a doctor. If condition worsens or does not improve within 7 days, discontinue use and consult a physician. |
| NFPA 704 (fire diamond) | 1-1-0 |
| Autoignition temperature | 445 °C |
| Lethal dose or concentration | LD50 (oral, rat): 100 mg/kg |
| LD50 (median dose) | LD50 (median dose): 354 mg/kg (rat, oral) |
| PEL (Permissible) | 5 mg/m³ |
| REL (Recommended) | 1–2.5 mg daily |
| IDLH (Immediate danger) | No IDLH established |
| Main hazards | May cause allergic skin reaction; causes eye irritation. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | eye", "pregnancy", "driving", "kidney", "liver |
| Signal word | Warning |
| Hazard statements | No hazard statements. |
| Precautionary statements | Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin unless directed by a doctor. Discontinue use if irritation or rash develops. If symptoms persist, consult a healthcare professional. |
| NFPA 704 (fire diamond) | 1-0-0-N |
| Flash point | 230°C |
| Autoignition temperature | > 430°C |
| Lethal dose or concentration | LD50 oral, rat: 100 mg/kg |
| LD50 (median dose) | LD50 = 354 mg/kg (oral, rat) |
| NIOSH | MN2600000 |
| PEL (Permissible) | PEL: Not established |
| REL (Recommended) | 10 mg |
| IDLH (Immediate danger) | No IDLH established. |
| Related compounds | |
| Related compounds |
Cortisone
Prednisolone Prednisone Dexamethasone Betamethasone |
| Related compounds |
Prednisolone
Cortisone Prednisone Dexamethasone Betamethasone |