MSDS for Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate

Identification

Product Name: Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate
Chemical Family: Steroidal compound
Synonyms: Not commonly found under alternate names
Recommended Use: Research chemical, chemical synthesis intermediate
Supplier: Details available upon request from distributor or manufacturer
Emergency Contact: Refer to company-specific emergency phone number
CAS Number: Search reliable chemical databases for precise registry
Product Code: Stocked under laboratory reference codes

Hazard Identification

Status: Classified as hazardous under GHS regulations when unlabelled or handled without protection
Risk Phrases: May cause respiratory, skin, or eye irritation; potential reproductive toxicity based on structural analogues
Routes of Entry: Inhalation, ingestion, skin absorption
Target Organs: Respiratory system, skin, mucous membranes
Signal Word: Warning
Pictogram: Exclamation mark (irritant)
Potential Health Effects: Acute exposure can cause redness, coughing, discomfort
Chronic Effects: Prolonged handling can impact hormonal systems based on structural similarity to known compounds
Environmental Hazards: Possible aquatic toxicity; further studies warranted

Composition / Information on Ingredients

Chemical Identity: Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate
Concentration: Typically supplied greater than 95% by weight in pure form
Impurities: Minimal, as per batch-specific certificate of analysis
Molecular Formula: C20H29NO3
Molecular Weight: Approx. 331.45 g/mol
Other Ingredients: No stabilizers or additives commonly present

First Aid Measures

Inhalation: Move to fresh air immediately; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash area thoroughly with soap and water
Eye Contact: Rinse cautiously with water for several minutes; consult a health care provider if irritation develops
Ingestion: Rinse mouth, do not induce vomiting, consult medical personnel
Note to Physician: Treat symptomatically; symptomatic and supportive care recommended

Fire-Fighting Measures

Suitable Extinguishing Media: Use CO2, dry chemical, foam, or water spray
Specific Hazards: Combustion may produce toxic fumes including nitrogen oxides, carbon oxides
Protective Equipment: Firefighters use full protective gear and self-contained breathing apparatus
Special Procedures: Prevent runoff from entering drains or water sources

Accidental Release Measures

Personal Protection: Put on gloves, laboratory coat, safety goggles, and use proper ventilation
Spill Cleanup: Collect spilled material with absorbent pad, sweep residue into clearly labeled chemical waste container
Environmental Precautions: Block entry to drains, surface water, and soil
Decontamination: Wash area with detergent and plenty of water after removal

Handling and Storage

Handling: Keep away from open flames, sparks, and hot surfaces. Minimize dust and aerosol formation. Practice good hygiene: wash hands before eating, drinking, smoking, or using the toilet.
Storage: Store in a tightly sealed container, away from moisture, direct sunlight, and incompatible chemicals such as oxidizing agents. Keep at recommended temperature stated by manufacturer, usually room temperature or cooler. Ensure storage area is ventilated. Restrict access to trained personnel.

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood, local exhaust, or adequate general ventilation systems
Personal Protective Equipment: Gloves (nitrile or neoprene recommended), chemical splash goggles, lab coat, and closed-toe footwear
Hygiene Measures: Remove contaminated clothing and wash skin after handling
Respiratory Protection: Use NIOSH-certified respirator if dust or aerosols expected
Exposure Limits: No official occupational exposure limit data, apply precautionary limits for uncharacterized research compounds

Physical and Chemical Properties

State: Solid
Appearance: White or off-white crystalline powder
Odor: Odorless or faint chemical scent
Odor Threshold: Not available
Melting Point: Typically in the range of 190-215°C based on purity and literature
Boiling Point: Decomposes before boiling
Solubility: Poorly soluble in water; soluble in common organic solvents such as ethanol, chloroform, DMSO
Vapor Pressure: Not significant at room temperature
pH: Not applicable in solid form
Partition Coefficient (log Kow): Estimated high hydrophobicity based on structure
Density: Around 1.1–1.3 g/cm³
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended conditions; decomposition may occur on exposure to intense heat
Reactivity: No hazardous reactivity under normal conditions
Conditions to Avoid: Excess moisture, elevated temperatures, open flames
Incompatible Materials: Strong acids, strong oxidizing agents
Hazardous Decomposition Products: Thermal decomposition releases carbon monoxide, carbon dioxide, nitrogen oxides

Toxicological Information

Acute Toxicity: Not fully evaluated; no animal oral LD50 data available
Skin Corrosion/Irritation: Possible irritation based on related steroid analogues
Eye Damage/Irritation: Redness and tearing possible after direct contact
Respiratory Sensitization: Inhalation may cause temporary respiratory distress
Repeated Dose Toxicity: Possible hormonal effects, use caution until full data available
Mutagenicity: Insufficient data
Carcinogenicity: No evidence available, avoid chronic exposure
Reproductive Toxicity: Possible risk inferred from structure, especially in research settings

Ecological Information

Ecotoxicity: Limited results; structurally related chemicals suggest risk to aquatic organisms in case of release
Persistence and Degradability: Not readily biodegradable in the environment, may persist in soil/water
Bioaccumulation Potential: Structure suggests potential to bioaccumulate
Mobility in Soil: Likely low since insoluble in water, binds to soil organics
Other Adverse Effects: Exercise caution to prevent environmental contamination

Disposal Considerations

Disposal Methods: Dispose through licensed chemical waste contractor; do not discharge uncontrolled to environment or drains
Contaminated Packaging: Handle packaging as hazardous waste; decontaminate before recycling
Legal Requirements: Follow local, regional, and national disposal regulations
Precautions: Work in authorized facilities trained to manage chemical and pharmaceutical waste

Transport Information

UN Number: Not assigned unless transported in bulk or mixed hazardous forms
Shipping Name: Research chemical, not regulated for small quantities but check current DOT, IATA, and IMDG regulations
Hazard Class: Not classified under standard transportation rules; use caution on documentation
Packing Group: None specified unless mixed with hazardous substances
Marine Pollutant: Avoid marine release as conservative protection
Special Transport Precautions: Use sealed, properly labeled packaging with absorbent material

Regulatory Information

TSCA Status: Research chemicals usually require notification to EPA before commercial use
EU REACH: Consult importer or manufacturer for registration status
OSHA Hazard Communication: Meets criteria for hazardous chemical under US regulations
SARA Title III: Not listed, but best practices require emergency planning and notification for research lab quantities
International Inventories: Product not typically listed under global chemical registries; consult national authorities
Labeling Requirements: Follow labelling as research-use only, handle as hazardous substance at all times
Other Local Requirements: State, province, or municipality may set additional handling standards or reporting obligations