Prednisolone-21-acetate came out of the surge in steroid research during the mid-20th century, a time when scientists looked to design drugs that tackled inflammation with fewer harsh side effects. Walking through medical literature from that period, it's not hard to see the excitement—pharmaceutical labs managed to tweak steroid molecules and unlock compounds like prednisolone, which brought real breakthroughs. Acetylating the 21-hydroxyl group helped control steroid activity for some formulations, and this idea continues to shape corticosteroid treatments. Watching steroid chemistry evolve showed the value of steady, focused work in drug discovery. The fact that this compound still shows up in recent clinical and tech papers underlines staying power forged by good old trial and error in lab benches and animal studies.
Prednisolone-21-acetate acts as a derivative of prednisolone, with a small molecular tweak that changes how it behaves inside the body. Usually found as a white to off-white powder, it stands out in the pharmaceutical market because it brings targeted glucocorticoid activity without breaking down too quickly. As a corticosteroid, it handles all sorts of clinical requests—injections, crafted tablets, even topical solutions. You bump into its name in hospital pharmacies, research supply catalogs, and animal health products. I remember summer internships where the big glass jars of this substance felt almost like old companions, always called for in anti-inflammatory panels and lab demonstrations. For folks working with animal models or formulating human medications, having this acetate handy means you can bridge the gap between experimental control and practical treatment.
Prednisolone-21-acetate comes as a fine powder, generally stable and only lightly soluble in water, but it blends into organic solutions with ease. This extra acetate tail bumps its molecular weight and adds a smidge of hydrophobicity, meaning folks handling it in a lab juggle solubility and stability issues, especially during scale-up. It holds together well under standard conditions, usually showing no degradation just from staring at it on a shelf, though high heat or strong pH can leave a mess. Chemists appreciate its unique IR and NMR signatures, which help confirm purity, and experience shows that it handles routine filtering, weighing, and blending without much fuss. Still, you want dry gloves and gentle handling—modern labs don’t want to waste pricey steroid powders on careless spills.
Bottles and boxes holding prednisolone-21-acetate shout out purity numbers: 98% minimum finds the sweet spot for research, while pharmaceutical grades sometimes push higher—think HPLC confirmation and impurity thresholds. Labels display storage advice, hazardous symbols, and detailed CAS numbers. Reputable suppliers note batch numbers and expiry dates, which sound boring until you land in a regulatory audit where every scanned barcode matters. Safety data sheets attached to shipments stack up the legal details, but in a busy lab or pharmacy, clear markings and robust traceability remain what staff actually rely on. These practical steps ensure no surprises when mixing, weighing, or dosing—just the basics, done right.
Most routes to prednisolone-21-acetate start by esterifying prednisolone itself with acetic anhydride or comparable acetyl donors, using mild warmth and solvent systems to nudge yields higher. A working day in the synthesis lab shows how the reaction can be tuned with careful pH adjustment, gentle agitation, and solid purification steps. Silica gel chromatography often pulls the main compound away from side products, letting chemists hit quality targets efficiently. Waste disposal, solvent recovery, and glassware cleaning pile up, and it's clear that scaling these reactions for industry-scale production requires as much logistical muscle as chemical insight. Watching the operations reminds us that real-world chemistry runs on teamwork—skilled hands, detailed records, and relentless focus on quality checks.
Prednisolone-21-acetate lends itself to further modifications, including hydrolysis (breaking back to prednisolone), oxidation, or selective halogenation. Medicinal chemists use this molecule as a starting block for specialty analogues, some designed to last longer, some tuned for local rather than systemic effects. Tackling these transformations day in and day out keeps chemists busy with glassware and analytics, chasing tweaks that improve solubility, activity, or absorption. Unlike blockbuster chemical reactions where big color changes happen, steroid chemistry rewards patience and careful thin-layer chromatography. It pays off, slowly, in analogs with clinical value or compounds that open fresh research tracks.
Many know prednisolone-21-acetate by alternative names: prednisone acetate, prednisolonum aceticum, and trade names that shine in regulatory filings or catalog entries. These synonyms pop up as you search medical or research records, so precise language matters. Navigating databases or ordering inventory means knowing which label matches which bottle—a mix-up can sink research budgets or trigger compliance headaches. Practical experience in the field says that seasoned pharmacists and research technicians keep running lists of alternative names pinned to benches and fridges. This habit saves time and shrinks error rates in hectic work environments.
Handling prednisolone-21-acetate means following chemical hygiene plans, local biosafety rules, and hazard guidelines spelled out in safety data sheets. Gloves, goggles, powder hoods, and air exchange systems form the backbone of safe operations. Dosing mistakes or inhalation risk matter because corticosteroids impact human metabolism even in trace amounts. Hospital settings treat this material as they might handle concentrated API powders—no shortcuts, all spills logged and cleaned up to standard. Training new staff usually starts with real-world demos, not just reading safety binders, and supervisors watch technique for lapses. Regulatory audits seize on safety shortcuts, so culture and vigilance shape safe handling just as much as formal policy.
Doctors reach for prednisolone-21-acetate to fight inflammation in conditions ranging from arthritis to allergic reactions. Veterinary clinics and animal researchers use it for managing swelling and immune responses in models or livestock. Formulation scientists can tailor this molecule for slow-release suspensions, injections, or topical treatments where fast breakdown would reduce its impact. Speaking with clinicians and visiting production lines reinforces how much practical dosing and patient response matter—some formulations excel because they match local needs better than older, plain versions. Field experience suggests that the demand for synthetic corticosteroids with stable dosing options shows no signs of fading, especially in settings with limited access to newer biologics.
My time in academic labs exposed the hunger for reliable prednisolone analogues—researchers test them in cell cultures, animal models, or formulation trials. These experiments measure performance against other corticosteroids, seeking trade-offs between anti-inflammatory punch and side-effect risks. Drug development teams hunt through chemical space, tweaking ester groups or ring structures. Industry and academia partner up to run blinded studies and toxicology panels, and journal articles build out long bibliographies on structure-activity relationships. Some research focuses on bioavailability and local delivery, especially for lung, skin, or ocular applications where targeted action reduces systemic downside. The molecule remains a workhorse, even as newer options pull headlines, and the research grind stretches into grant renewals and fresh collaborations each year.
Toxicology groups analyze how prednisolone-21-acetate affects organs, immune profiles, and chronic dosing cycles. Animal studies point to risks: rapid bone density loss, sugar spike, adrenal suppression, all of which show up on the radar for regulatory review. Dose-response trials run through a battery of screens looking for genotoxic or reproductive risks. Clinical teams rely on these stats when doctoring dosing regimens for at-risk groups, such as kids or the elderly. First-hand lab experience reminds everyone that “safe” really means “cautiously controlled”: every corticosteroid packs a punch, and reliable handling means learning through detailed documentation, cross-team communication, and a visible commitment to transparency.
Emerging research on smart drug delivery and prodrug design keeps prednisolone-21-acetate relevant. Companies tinker with nanoparticle carriers or new ester derivatives looking to tune release rates or target tissues with more control. Watching recent conferences, the drive keeps shifting toward making steroid therapies safer for long-term use—lowering risk of metabolic or immune system fallout. Academic groups tie clinical findings to new chemical ideas, spinning out collaborations and pushing for funding into steroid alternatives. For students and scientists entering the field, working on corticosteroids like prednisolone-21-acetate offers both a solid research foundation and a glimpse at the next wave of safer anti-inflammatory therapies. The work marches forward, powered by experiments, careful records, and the hands-on experience that textbooks rarely capture.
Many folks have heard of steroids, but not everyone knows the difference between anabolic steroids that make headlines in sports and corticosteroids prescribed by doctors. Prednisolone-21-acetate fits into the second group. This medication often steps up to help the body handle conditions sparked by runaway inflammation. Think asthma flares, allergic skin problems, or even nasty auto-immune attacks—prednisolone-21-acetate gets called off the bench for these jobs.
Prednisolone-21-acetate works by calming an overactive immune system. Too much inflammation can damage organs and make simple issues feel overwhelming. Rheumatoid arthritis, lupus, and inflammatory bowel disease—the names may sound different, but all can lead to periods where the immune system just won’t quit. With these conditions, doctors count on prednisolone-21-acetate for its power to cut swelling and pain, giving people a break from the relentless cycle of flare-ups.
Prednisolone-21-acetate isn’t the only corticosteroid out there, but it stands out for a few practical reasons. Its chemical makeup lets it do its job without turning into a long-term burden for the liver. The acetate form makes it easier for the body to absorb, and doctors know how it acts in the system, which helps them plan treatments. This predictability turns out to be pretty important for folks with chronic illnesses who might need steroids on and off for years.
I remember my own relatives dealing with asthma and allergies needing steroids during tough stretches. Relief arrives fast, but there’s always a trade-off. Long-term steroid use opens the door to weight gain, weak bones, high blood sugar, and even mood swings. So, prednisolone-21-acetate isn’t something to take lightly. Good doctors track dosage, watch for risk factors, and try to taper the medicine down as soon as possible. According to studies published in journals like The Lancet, regular monitoring can lower the risk of serious complications.
Prednisolone-21-acetate serves a purpose. It may not cure chronic disease, but it buys time and comfort, especially for patients who have no other options during severe flare-ups. Decisions about taking it should happen face-to-face with a healthcare professional who understands both the science and the patient. Sticking close to prescribed plans, focusing on the shortest possible courses, and pairing steroids with lifestyle tweaks—these steps can make a big difference.
Newer medicines hit the market every year, aiming to deliver the same benefits without all the baggage of traditional steroids. For now, prednisolone-21-acetate remains a workhorse in clinics worldwide. So, anyone given this prescription should pay careful attention, ask questions, and look for the support they need to stay healthy, both now and down the road.
Prednisolone-21-Acetate gets prescribed often for inflammation, allergies, and various autoimmune problems. It comes with a long list of possible side effects, many of which start showing up quickly. Most folks notice weight gain, fluid retention, and a bigger appetite almost right away. Some people say food cravings hit them out of nowhere. A friend of mine on this drug had to buy bigger pants—her appetite just didn’t quit. Face puffiness, often called “moon face,” is another change people mention. It sneaks up during longer courses but becomes obvious in the mirror.
Mood swings and trouble sleeping show up often for people using Prednisolone-21-Acetate. Some report feeling jittery, anxious, or even irritable. Others struggle to fall asleep or stay asleep, lying awake for hours. Medical research backs up these personal stories. Studies published by the Mayo Clinic found that corticosteroid therapy can increase risk of insomnia, mood changes, and even depressive feelings. Sleep loss drags down quality of life and can make other side effects feel worse.
Heartburn, nausea, and even ulcers appear on the side effects list. People often complain about stomach pain or acid reflux, especially when taking the drug on an empty stomach. Taking Prednisolone-21-Acetate with food usually eases these problems. Long-term use raises the risk of ulcers and bleeding in the gut, according to data published by the Cleveland Clinic. Doctors often recommend adding stomach protectants if longer therapy looks likely.
Prednisolone-21-Acetate doesn’t just target problem inflammation: it also breaks down healthy bones and muscles over time. A close relative taking it for months noticed back pain and a loss of strength in her legs. Medical research links corticosteroids to osteoporosis, thinning of bones, and higher fracture risk. Supplements like calcium and vitamin D, and weight-bearing exercise, serve as helpful countermeasures. These steps matter a lot for older adults who already face higher bone loss risk.
Another nasty surprise lurks in the way corticosteroids dampen the immune system. Respiratory infections, slow-healing wounds, and oral thrush pop up more often, especially during longer courses. In my own work in a clinic, patients with cuts or minor skin issues told us scratches lingered and infections took hold faster. The Centers for Disease Control and Prevention advise people to wash hands frequently and get recommended vaccines to lower risk while using drugs like Prednisolone-21-Acetate.
Prednisolone-21-Acetate can push blood sugar up, even in people without a history of diabetes. My uncle saw his blood sugar spike after starting therapy. Studies support this experience: corticosteroids can lead to new cases of diabetes and make existing diabetes harder to control. Blood pressure also climbs, sometimes without any warning. Doctors monitor both closely, adjust medications, and sometimes recommend dietary changes.
Anyone taking Prednisolone-21-Acetate should keep regular appointments and report changes, no matter how small. Journaling symptoms, sticking to doctor advice, and making diet and lifestyle tweaks help reduce the impact of common side effects. It pays to ask questions and bring up anything that doesn’t feel right—the body often signals trouble before lab results do. Trusted health resources like the CDC and Mayo Clinic offer reliable information for patients and families navigating steroid therapy.
Prednisolone-21-acetate catches the attention of healthcare professionals and patients alike because it deals directly with reducing inflammation inside the body. It’s part of the corticosteroid family, and experience with steroids suggests that right dosing and method of delivery change everything for outcomes and safety. Improper handling can mean everything from stomach issues to weakened bones over time.
Doctors typically prescribe this medication as either an oral tablet or a suspension for people who have trouble swallowing pills. Giving the medicine by mouth lets the active ingredient get where it needs to act—fast, but not so quickly as to cause a shock to the system. The gut absorbs it pretty efficiently, which delivers reliable blood levels for treating things like asthma flare-ups or serious allergies.
Decades of patient cases have taught us that corticosteroids like prednisolone work best when the dose fits the patient’s age, weight, and condition. A child dealing with croup doesn’t need the dosage that an adult managing severe autoimmune disease would use. Medical professionals often start with a bigger dose to get symptoms under control, tapering it off to lower doses as improvement happens. Skipping tapering or stopping too fast can throw the body’s natural hormone production into chaos—sometimes with consequences like fatigue, body aches, or even adrenal crisis.
My own time working in pharmacy made it obvious: interactions sneak up easily. Other medications, including certain antifungals and anti-seizure drugs, can change prednisolone’s effectiveness or cause side effects to spike. Taking prednisolone with NSAIDs increases risk for stomach bleeding. People with diabetes might see blood sugar rise because of this steroid. Kidney or liver disease changes how long the drug stays in the system, too, demanding more frequent check-ins with the doctor.
The best outcomes happen when the lines of communication stay wide open between patient and provider. This isn’t just about reading the information leaflet—ask about signs of infection, long-term bone health, how to handle missed doses, and ways to manage side effects. Strong support from healthcare teams—from pharmacists to nurses—keeps surprises to a minimum.
There’s always more to learn as research and better forms of steroids emerge. Until then, a partnership between medical professionals and those who count on prednisolone-21-acetate remains the most effective tool. Careful monitoring, honest questions, and patient-specific tweaks hold the real key.
Anyone who’s spent much time following prescriptions knows that every drug carries a story. Prednisolone-21-acetate offers powerful benefits for people wrestling with serious inflammation, but it also carries warning signs that deserve respect. Years ago, a close relative—already worn out by diabetes—found herself prescribed steroids for an out-of-control autoimmune condition. That’s where the real-world effects of medications like prednisolone go from words on a label to a game-changer for families. The facts follow you home, into the kitchen, as you adjust every meal.
Let’s break down why doctors keep a close eye on folks who get prescribed prednisolone-21-acetate. One major reason lies in the body’s stress system. Steroids mimic human hormones, shifting sugar, salt, and energy levels. Anyone living with diabetes needs to monitor blood sugar. Steroids push glucose higher, sometimes to dangerous levels, making insulin schedules unpredictable. Blood pressure ticks up, too, and fluid can build up in tissues, which pushes the heart harder, especially in folks with prior heart trouble. Relatives with hypertension or heart issues often end up charting numbers every night, hoping readings stay within range.
Kids and elderly adults live with a whole different set of risks. Bones grow soft or brittle with long-term steroid use. As teenagers stretch toward adulthood, high doses can stop growth spurts early. Grandparents sometimes find themselves staring at surprise fractures and mysterious muscle weakness, unsure how a small pill quietly eroded their bones.
Catching a cold doesn’t mean the same thing to everyone. Those relying on prednisolone-21-acetate take a bigger gamble: their immune system slows down, leaving doors open to infections that others brush off without much thought. Infections spread faster, take longer to recover from, and sometimes turn severe. History shows that even a simple virus, easy for most, brings real danger to folks living with immunosuppression. Some of the hardest days in hospitals come when routine infections turn into life-threatening situations, with families left waiting for updates outside ICU doors.
Pills rarely arrive alone. People dealing with arthritis, asthma, or allergies often have a shelf’s worth of bottles. Steroids spark reactions with antifungal drugs, some blood thinners, and certain vaccines. Even common painkillers like ibuprofen can increase risks—stomach bleeds, ulcers, and more. Healthcare workers make daily calls sorting through these combinations, trying to untangle which drugs raise new risks when steroids come into the mix.
Pregnant people, those with active infections, and people with active ulcers or psychiatric conditions face bigger risks. Reading through warning labels, you recognize stories of people pushed into manic episodes or struggling with sleepless nights once a steroid cycle began. The mental side effects often catch families off guard. Doctors ask careful questions before writing these prescriptions for a reason, looking for signs of mood disorders or recent psychosis.
No one wants to take on more trouble while trying to chase relief. The best path forward includes honest conversations with care teams, strict monitoring, lifestyle changes, and sticking with recommended doses. Community support and education about these risks matter even more than the fine print on a bottle. What starts as a small act in the clinic can ripple through whole families—and sometimes, that makes all the difference.
Prednisolone-21-acetate, a corticosteroid, often steps into the spotlight during flares of inflammation, autoimmune struggles, or after certain organ transplants. Its job is heavy-duty—tamping down the body's immune response. Yet, the presence of this drug inside a daily pillbox can cause a few ripples, especially with other medications nearby.
Over the years, sitting across from people sorting trays of daily pills, I've seen how drug interactions become invisible troublemakers. Someone feeling jittery or suddenly with blood sugar spikes, only to discover that prednisolone had been throwing a wrench with a diabetes medication. People on blood thinners like warfarin may find themselves at risk for bleeding because steroids make warfarin act more unpredictably. Antibiotics such as rifampin can sweep through and cut steroid levels down, leaving inflammation to reignite unexpectedly.
A big reason this matters: many folks with long-term health problems stack up prescriptions. A person with rheumatoid arthritis might already be juggling pain meds, immunosuppressants, and medicine for high blood pressure. Add corticosteroids, and the chemical juggling act tightens.
Corticosteroids can mess with the way the liver handles many drugs. They tend to boost or dim the strength of others. Diabetics get a raw deal because steroids push up blood sugar, wrecking careful glucose control and forcing rapid insulin or oral medicine adjustments. Live vaccines stop being safe if the immune system runs low on defenses from steroids—suddenly, what should protect might trigger illness.
Some medicines can quietly raise steroid levels, risking infection, weight gain, or mood swings. Antifungals like ketoconazole keep steroid levels higher for longer. Seizure drugs and certain antibiotics cut those levels, which risks losing control over inflammation or rejection episodes after an organ transplant. Even the humble NSAID—often relied on for joint pain—can team up with steroids to cause stomach ulcers or bleeding.
Helping people avoid run-ins between their medicines takes more than a list of warnings. Real trust builds when everyone in the care circle—pharmacist, doctor, nurse—checks in, reviews the full medication bag, and looks out for duplicate efforts and unseen risks. Modern health systems flag some interactions, but plenty slip through unless someone asks and listens.
Encouraging open conversations between clinician and patient draws out over-the-counter supplements or herbal pills that could wreck delicate balance. Grapefruit juice, for example, gets little mention but can mess with steroid metabolism.
Preventing these interactions means knowing every medication on board, spotting changes in weight, energy, blood sugar, or mood, and scheduling regular check-ins when steroids come into play. Pharmacists remain a resource—often spotting risks before trouble starts. People deserve clear, honest talk about what steroid treatment could mean for their daily routine.
The world of medicine feels complicated, especially for anyone managing more than one condition. Combining medications like prednisolone-21-acetate with others doesn’t have to mean more stress—knowledge, regular reviews, and conversations with healthcare professionals allow people to steer clear of dangerous drug clashes, keeping treatment on the safest path possible.
| Names | |
| Preferred IUPAC name | [(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl acetate] |
| Other names |
Prednisolone acetate
Prednisolone-21-acetate Adasone Prednesol Predonema |
| Pronunciation | /prɛdˌnɪs.əˌloʊn ˈtwɛnti wʌn əˈsiː.teɪt/ |
| Preferred IUPAC name | [(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl acetate] |
| Other names |
21-Acetoxyprednisolone
Prednisolone acetate Hydrocortisone acetate Metacortandracin |
| Pronunciation | /ˌprɛd.nɪˈsoʊ.ləʊn ˈtʊɛnti wʌn ˈæs.ɪˌteɪt/ |
| Identifiers | |
| CAS Number | 125-02-0 |
| Beilstein Reference | 608737 |
| ChEBI | CHEBI:8376 |
| ChEMBL | CHEMBL1200449 |
| ChemSpider | 20639778 |
| DrugBank | DB01689 |
| ECHA InfoCard | 100.027.374 |
| EC Number | 206-984-0 |
| Gmelin Reference | Gmelin Reference: "82133 |
| KEGG | C16116 |
| MeSH | D011084 |
| PubChem CID | 10255 |
| RTECS number | UF8225000 |
| UNII | 62T278S1AQ |
| UN number | UN2811 |
| CAS Number | 125-02-0 |
| Beilstein Reference | 2763946 |
| ChEBI | CHEBI:8463 |
| ChEMBL | CHEMBL1204526 |
| ChemSpider | 6142 |
| DrugBank | DB00769 |
| ECHA InfoCard | Prednisolone-21-acetate (ECHA InfoCard: 100.028.407) |
| EC Number | 206-130-2 |
| Gmelin Reference | Prednisolone-21-Acetate Gmelin Reference: 84630 |
| KEGG | C07271 |
| MeSH | D004617 |
| PubChem CID | 6603888 |
| RTECS number | UF5950000 |
| UNII | 34593Y40QV |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | urn:CXTN:CNQ4I5784R |
| Properties | |
| Chemical formula | C23H30O6 |
| Molar mass | 418.49 g/mol |
| Appearance | white to practically white crystalline powder |
| Odor | Odorless |
| Density | 1.3 g/cm3 |
| Solubility in water | Insoluble in water |
| log P | 1.54 |
| Acidity (pKa) | 12.51 |
| Basicity (pKb) | 15.07 |
| Magnetic susceptibility (χ) | -749.4×10^-6 cm³/mol |
| Refractive index (nD) | 1.563 |
| Dipole moment | 8.56 Debye |
| Chemical formula | C23H30O6 |
| Molar mass | 402.477 g/mol |
| Appearance | White or practically white crystalline powder |
| Odor | Odorless |
| Density | 1.34 g/cm³ |
| Solubility in water | Insoluble in water |
| log P | 1.72 |
| Acidity (pKa) | 12.59 |
| Basicity (pKb) | 13.57 |
| Magnetic susceptibility (χ) | -755.0e-6 cm³/mol |
| Refractive index (nD) | 1.524 |
| Dipole moment | Dipole moment of Prednisolone-21-Acetate: **6.62 D** |
| Thermochemistry | |
| Std enthalpy of formation (ΔfH⦵298) | -861.7 kJ/mol |
| Std molar entropy (S⦵298) | Prednisolone-21-Acetate std molar entropy (S⦵298): 567.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | NULL |
| Pharmacology | |
| ATC code | H02AB06 |
| ATC code | H02AB06 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation. |
| GHS labelling | GHS02, GHS07 |
| Pictograms | `CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3(F)C(=O)CO)[C@@]2(C)C1` |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P362+P364, P501 |
| Flash point | Flash point: **235.8 °C** |
| Lethal dose or concentration | LD50 oral (rat): 1670 mg/kg |
| LD50 (median dose) | mouse oral LD50 3250 mg/kg |
| NIOSH | SAF2200 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 40 mg |
| Main hazards | Causes serious eye irritation. May cause respiratory irritation. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | H319,H335,H336 |
| Signal word | Warning |
| Hazard statements | Hazard statements: H302, H361 |
| Precautionary statements | P264, P270, P280, P302+P352, P305+P351+P338, P337+P313, P332+P313, P362+P364 |
| Flash point | Flash point: 174.2 °C |
| Lethal dose or concentration | LD50 (oral, rat) = 1950 mg/kg |
| LD50 (median dose) | LD50 (median dose) Oral Rat: 1950 mg/kg |
| NIOSH | VO5950000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | Prednisolone |
| Related compounds | |
| Related compounds |
Prednisolone
Prednisone Prednisolone acetate Prednisolone sodium phosphate Hydrocortisone Methylprednisolone |
| Related compounds |
Prednisolone
Prednisolone sodium phosphate Prednisolone acetate Prednisolone succinate Prednisone |
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