Triamcinolone Acetonide: Looking Beyond the Label

Historical Development

Triamcinolone acetonide started its journey in the pharmaceutical world over half a century ago. The mid-twentieth century was a golden era for corticosteroid discovery, and researchers didn’t just stumble across this molecule; they chased better ways to treat skin disease, allergies, and inflammation—a growing problem as society tackled everything from industrial solvents to new antibiotic allergies. Steroids back then offered a real leap forward, but their side effects hung over every doctor's head. Chemists tinkered in the lab, adding acetone and other side chains, searching for something that would tamp down the body’s overreactions without sparking new problems. Triamcinolone acetonide came out of this work as a promising candidate—strong against the source of inflammation, less likely to raise blood pressure than older kinds.

Product Overview

If you look at any drug store shelf, you’ll see triamcinolone acetonide in all sorts of forms: creams, ointments, nasal sprays, dental gels, injectables. Each serves a different need. People with chronic rashes often find a steroid cream more practical than a tablet—less strain on the rest of the body, direct relief for the sore spot. Dental gels reach right into gum tissue, calm down ulcers in places where most pills can’t touch. Clinics keep the injectable form for stubborn joint pain when nothing else works. The variety shows real-world demand. Health isn’t one-size-fits-all, and this compound grew into its market because so many people need help managing allergic triggers and lingering inflammation.

Physical & Chemical Properties

Triamcinolone acetonide looks like a fine, white powder with almost no smell. It doesn’t dissolve well in water, so manufacturers must blend it with oils, alcohols, or other carriers for the different product types. Chemical structure makes a big difference—this isn’t the raw hormone pulled from glands; it’s a fine-tuned molecule with extra groups clinging to the main steroid backbone. The acetate ring attached helps it stay put in the skin or mucous membranes, which means fewer doses needed compared to older, less stable relatives. Stability under light and air gives it a longer shelf life in pharmacies and hospitals. In practical terms, these details affect how doctors prescribe and how patients use it—creams likely stick around in the skin longer, while nasal sprays clear quickly so folks can get back to breathing.

Technical Specifications & Labeling

Quality standards don’t come from thin air. Pharmacopeias spell out what counts as pure, how much of the main ingredient should sit in any product, and which impurities crop up if synthesis isn’t careful. Labels do more than share the generic name—they need to make things clear: concentration, list of inactive fillers, allergy warnings, directions spelled out for folks who need simplicity over jargon. These technical details help pharmacists avoid confusion and prevent mistakes that could endanger frail folks or young kids. Standardized labeling also makes importing and exporting easier, which keeps costs down for clinics serving low-income patients.

Preparation Method

The lab procedure behind triamcinolone acetonide calls for careful chemistry. Starting from a simpler steroid, an acetone group gets stitched onto the molecule through a controlled reaction—think heating, mixing with acidic catalysts, extracting with solvents, and then purifying with trickier steps like crystallization or chromatography. These steps matter because the final product can’t have leftover solvents or unreacted starting chemicals. Pharmaceutical companies double down on these controls using spectroscopy and other analytic tools. Long hours go into pilot runs and quality checks; small mistakes in process can mean a batch that never reaches the shelves. I know people behind the scenes who still run extra quality tests—one misstep might spell months of extra scrutiny from health regulators.

Chemical Reactions & Modifications

Once triamcinolone acetonide enters the market, there’s still work left for chemists. The molecule can swap its carriers, or get altered again with esters to change its absorption pattern. Subtle tweaks mean a version that stays local for skin creams, but a fast-acting one for inhalers. These chemical shifts set apart a topical gel from an eye drop. Researchers have chased after derivatives with fewer side effects, hoping to soften long-term risks like skin thinning or immune suppression. Every change comes with its own headaches: chemical stability, process complexity, and changes in pharmacokinetics—how fast the body uses and gets rid of the drug. These factors shape which products turn into medical mainstays, and which remain niche solutions.

Synonyms & Product Names

Doctors and patients sometimes hear this drug called by other names: Kenalog, Aristocort, Nasacort. Generic labels may just read “triamcinolone acetonide.” Pharmacies often juggle multiple branded choices, and part of navigating health care is knowing that different names can mean the same medicine. This isn’t corporate branding; the reason for the spread is regulatory and practical—companies develop distinct formulations for distribution in different regions, and regulators sign off on brand names to avoid mix-ups with unrelated drugs. Clear records and education help people avoid doubling up on the same active ingredient, and prevent mix-ups especially in polypharmacy cases.

Safety & Operational Standards

Steroids come with their own risk baggage, and triamcinolone acetonide demands care in how it’s handled. Clinics stick to medical guidelines, using gloves with topical preparations and discarding unused injectables safely. Hospitals require staff to double-check doses, particularly for children and the elderly. Unintended absorption or overuse leads to side effects like skin thinning, delayed wound healing, and even suppression of the adrenal glands if misused over long periods. Clear training, sharp labeling, and review checklists add a layer of safety that wasn’t around back in the early decades. Even at home, patients must pay close attention to directions and avoid “topping up” on their own.

Application Area

Daily life brings a surprising number of uses for triamcinolone acetonide. Dermatologists lean on it for eczema, psoriasis, and bug bites that don’t quit. Dentists keep it nearby for mouth ulcers that make every bite a misery. Rheumatologists inject it straight into joints to calm a rogue immune flare. Allergy specialists prescribe nasal sprays to fight off seasonal stuffiness. Inhalers help asthma sufferers who can’t tolerate broader-spectrum steroids. The value lies not just in its anti-inflammatory punch, but the flexibility to deliver relief exactly where the problem sits. Yet, doctors set firm boundaries; this isn’t a fix-all, and every application comes with its own limits and risks.

Research & Development

Triamcinolone acetonide keeps drawing attention in the lab. Researchers try to tease apart which molecular tweaks might cut side effects or improve targeting. New delivery systems pop up—microspheres, slow-release implants, even patches that hold the steroid in the skin longer. Academic papers debate how low a dose gives lasting relief versus risk. Some scientists chase better diagnostic markers for steroid response, hoping to avoid “trial and error” prescription. The push for new uses hasn’t stopped; off-label treatments for rare inflammation, efforts to pair the drug with antimicrobials for chronic wounds, all test the boundaries set decades ago.

Toxicity Research

Doctors and scientists never let down their guard on safety. Years of data cement triamcinolone acetonide’s place, but every patient brings a new challenge—metabolic quirks, inherited weaknesses, drug interactions. Animal models gave early warnings about systemic absorption and growth effects in young animals. Later studies sifted through case reports of skin thinning and systemic hormone disruption in sensitive groups. Regulatory bodies rely on periodic safety reviews, and major journals publish reminders that even small risks stack up in the broad population. Tools like pharmacovigilance databases now track rare but serious events—a luxury physicians of the past didn’t have. The lesson? Regular check-ins, measuring for blood sugar shifts, skin changes, or signs of immune suppression.

Future Prospects

Steroids won’t vanish from medicine any time soon, but triamcinolone acetonide’s spot in the toolkit keeps shifting. Next-generation delivery systems promise to cut dosing frequency, maybe even sidestep the tissue thinning many folks fear. Tailored medicine might one day predict who will benefit and who risks harm, adjusting dose and delivery to a person’s DNA. Green chemistry stands ready to clean up production, swapping in solvents and reagents with a lighter environmental footprint. Personalized care, greener manufacturing, and constant research into long-term health profiles will keep pushing development, and let doctors offer better results for each unique patient journey.



What is Triamcinolone Acetonide used for?

A Powerful Tool for Inflammation and Allergies

Triamcinolone acetonide stands out in the world of corticosteroids. Having worked in healthcare and spent years speaking to people with chronic inflammatory conditions, I’ve noticed how much relief a single medication can bring when nothing else seems to help. Triamcinolone acetonide works by calming the body’s immune response, which tends to spiral when allergies, arthritis, or skin flare-ups strike hard.

If you roll up your sleeve and look, a rash can appear in seconds from a trigger—think poison ivy or psoriasis. The same kind of inflammation that causes visible redness and swelling on the skin happens inside the joints or sinuses for many struggling with asthma or allergic rhinitis. Triamcinolone acetonide targets that overreaction, giving the body time to heal and settle down. Doctors often choose it for its strength in persistent cases where ordinary creams and pills just don’t cut it. Some folks use the cream version for eczema patches that refuse to clear up. Others receive injections to soothe swollen joints in rheumatoid arthritis.

Different Forms, Real-World Impact

There isn’t a one-size-fits-all solution for inflammation. Triamcinolone acetonide proves this with its many forms. In my experience, parents often reach for a nasal spray during spring allergies. The relief comes fast, kids can breathe, and the day gets easier. For someone who works outdoors or with their hands, a topical ointment can reduce cracked, painful skin. Dental professionals sometimes order a special paste for painful mouth ulcers so people can eat and talk comfortably again.

Asthma patients already understand how hard it gets when breathing feels like a losing battle. Using an inhaled version lets them avoid stronger steroid pills and their risk of side effects. Eye doctors even use a special formula to control swelling after surgery or with certain eye conditions.

Weighing Risks and Making Choices

No medication comes without risk. I’ve seen people develop thinner skin and more bruising with overuse of steroid creams, especially on the face or with repeated use in children. Blood sugar levels or blood pressure can swing in those using higher-dose injections. Triamcinolone acetonide works best under the guidance of a knowledgeable doctor. Skipping regular check-ins can land people in trouble, especially with long-term use.

Millions rely on this medication every year, so education matters. Pharmacists, nurses, and online resources now share guidance, breaking down how to use each form and spot side effects before they worsen. Patients benefit when they know to use just enough, at the right times, for the right length of days. Decisions often come down to weighing how badly the symptoms impact life versus the chance of side effects.

Improving Access and Educating the Public

Painful skin, aching joints, swollen airways—all of these steal focus from work and family. Triamcinolone acetonide brings relief, but people need accurate information and support to use it wisely. As science advances and more treatment options appear, spreading knowledge grows even more important. Community health classes, clear pharmacy labels, and well-trained health workers can all help people navigate their choices safely, restoring a sense of normal life when chronic inflammation threatens to take over.

What are the possible side effects of Triamcinolone Acetonide?

Everyday Experience With a Potent Corticosteroid

Triamcinolone acetonide finds a spot in many medicine cabinets—creams, nasal sprays, injections, even dental paste. Dermatologists, primary care doctors, and ear-nose-throat specialists all use it for conditions that just won’t calm down with ordinary measures. I remember getting my first prescription for a triamcinolone cream during a brutal bout of eczema. Relief arrived in hours, but I noticed pretty quickly that one simple medication could stir up a lot of questions about safety. Looking back, anyone handed a steroid like this should get the full rundown on what the risks can look like for real people.

Common Side Effects That Crop Up Quickly

Most folks rubbing triamcinolone acetonide into their skin are there to rein in itchy rashes or eczema, but over a few weeks, many start to see the most familiar downsides. Skin can thin out and bruise more easily, and stretch marks may turn up where the cream gets used daily. I’ve spoken with patients who ended up with dark patches or tiny blood vessels showing near their elbows and knees. Stinging and burning often show themselves for the first few days but tend to fade away. These changes rarely last if a person stops using the cream before several months go by.

Serious Risks With Stronger Doses or Long-Term Use

Nasally inhaled or injected triamcinolone brings much stronger effects. Inhaled types can irritate the throat, cause a hoarse voice, or prompt sinus infections for folks already sensitive. Oral and injectable steroids don’t stay local. Over time, a person risks trouble with high blood sugar, weight gain, swelling in the face, and muscle weakness—an obvious concern for folks with diabetes or high blood pressure. More than once, I’ve seen patients develop slow wound healing and paper-thin skin that tears at the slightest friction.

Doctors worry most about steroids disrupting the natural rhythm of your body's hormone system. Regular use can weaken your immune response, leading to a higher risk for infections that usually wouldn’t be a problem. Kids using triamcinolone without close supervision sometimes hit bumps in their growth, and teens are at risk for acne that no over-the-counter wash will treat. Less common, but still possible with stronger doses, you could see changes in mood and sleep—mood swings, insomnia, even a bout of anxiety or depression.

Who Gets Hit Hardest

The people running into trouble with triamcinolone often stretch their prescriptions over many weeks, use it on sensitive areas, or combine it with other corticosteroids. Infants, older adults, and anyone with immune issues walk a trickier road. Many patients go years without learning that using more than prescribed or skipping check-ups for repeat refills can pile on new side effects.

Smart Practices to Lower the Risks

Doctors and pharmacists don’t say “use the lowest dose for the shortest time” just as empty advice. Keeping triamcinolone to the smallest area possible and limiting how long it’s used won’t solve every problem, but it gives the skin time to recover. Rinsing the mouth after inhalers, avoiding broken skin, checking blood sugar for people with diabetes, and using moisturizer to counter dry patches—these small steps keep things manageable. Open conversations with a healthcare provider help spot complications before they snowball, which often means better results for both patient and doctor.

How should Triamcinolone Acetonide be applied or used?

What I’ve Learned About Using Triamcinolone Acetonide

Triamcinolone acetonide steps up when itchy rashes, eczema, or stubborn patches of skin refuse to calm down. Over the years, dealing with everything from poison ivy in the woods to surprise winter eczema flare-ups, I've seen this corticosteroid cream work its magic for family and friends. Trouble starts when folks treat it like a regular moisturizer or think more equals better. That seems harmless at first but can leave skin thinner, weaker, and crankier.

How Doctors Suggest Using Triamcinolone Acetonide

Most doctors lay out a clear plan: only use a prescribed amount, apply a thin layer on affected spots, and keep it away from healthy skin. People often ignore the instructions and slather it over wide areas, especially if the redness stings or itches a lot. That’s a shortcut to trouble. Thinned skin, wild hair growth in treated areas, or even lightening of skin patches can sneak up quick. As someone who’s seen friends misuse strong steroids, I always remind folks—stick to the smallest amount that actually works.

Application: More Routine Than Mystery

Every morning, before heading out, wash hands first, gently pat the inflamed skin dry, and only then run a fingertip over the spot using the prescribed quantity. Use just enough to cover that patch, then stop. Rubbing it in too hard or using bandages keeps medicine locked in, which sometimes brings side effects. Eyes, groin, face—these areas act differently and often need weaker versions or shorter courses. I’ve seen kids with rashes whose parents unknowingly reached for a strong version and ended up with burning or skin changes. Most specialists advise asking again before putting the tube anywhere off-label.

Side Effects People Often Overlook

Short-term relief feels great, but trouble can sneak up when folks don’t pay attention. Steroid creams like triamcinolone invite trouble if used longer than directed, especially on delicate skin. Keep an eye out for thinning skin, stretch marks, or unusual burning. Sometimes skin can pick up infections or even stop healing as quickly. I’ve heard dermatologists say these risks climb if you use a stronger dose than your doctor decided on. If anything looks off, call your clinic—don’t just hope it improves by itself.

The Facts: Safety Nets Worth Using

The U.S. Food and Drug Administration insists on clear warnings, because side effects aren’t rare. I’ve seen reports of parents using leftover cream on their kids without talking to a doctor, and that often backfires. Pharmacy boards and the Mayo Clinic suggest tossing old containers once a flare clears up, so no one reaches for the wrong thing later. Leaving medicine in easy reach creates mix-ups or accidents around little hands, so I always tuck these tubes up high.

Better Habits for Future Flares

Education changes everything here. Patients do better if healthcare workers break it down simply: smallest amount, shortest time, only on problem areas, always wash hands before and after. If a rash looks worse or pops up in new spots, it’s time to check in, not just reapply triamcinolone. Keeping open communication between patient and prescriber makes relapses less scary and outcomes better for everyone.

Can Triamcinolone Acetonide be used for children or pregnant women?

Understanding the Medication

Doctors prescribe Triamcinolone Acetonide for inflammation and allergic reactions. This corticosteroid pops up in nasal sprays, creams, injections, and dental pastes. Parents, caregivers, and expecting mothers might run into it while dealing with eczema, asthma, or stubborn allergies. On the surface, it sounds helpful. Scratching, swelling and rashes wear a person down fast, and nobody likes to see a child or loved one struggle with constant discomfort.

Questions and Concerns for Kids

Kids bounce back from scrapes and sniffles, but not every medicine fits their bodies or stages of growth. Steroids, including Triamcinolone Acetonide, pack a punch. They work by tamping down the body’s own response to irritation, which solves one problem but sometimes creates others. For children, doctors watch for slowed growth, weight gain, mood swings, or infections—side effects that might come from using strong steroids over time. One study published in Pediatrics examined inhaled corticosteroids and found that higher doses can slightly affect height, especially over long stretches. Skin creams or ointments get absorbed too, so even treatments on the outside can add up.

Pediatricians weigh risks and benefits carefully. They often start with the mildest option, and if Triamcinolone Acetonide enters the picture, they recommend the lowest dose possible for the shortest time. Parents should never use another family member’s leftovers on their child or stretch out prescriptions without talking to a doctor. That lesson came home for me when a neighbor’s son ended up with a skin infection from sharing eczema creams not meant for him.

What About Pregnant Women?

Pregnancy means reading every label twice. Triamcinolone Acetonide’s available data points toward caution. Research suggests that topical or inhaled steroids present less risk than taking them by mouth or injection. Still, anything absorbed by the mother can reach the developing baby. Some animal studies flagged a higher risk of low birth weight or birth defects, especially with heavy or frequent dosing. It’s tough to be certain because most human studies don’t include pregnant participants.

Every expecting mother’s situation looks different. Doctors consider the severity of symptoms, the kind of medicine, and any safer alternatives. Often, if a mild rash or allergy flare-up can be managed with moisturizers or other treatments, that's the route chosen. For stubborn cases—think severe asthma or aggressive skin conditions—Triamcinolone Acetonide sometimes remains the best tool. Specialists usually stick with the lowest strength and smallest area possible, and they keep close tabs throughout pregnancy. My sister-in-law felt anxious about every tube and bottle during her first trimester, but a frank talk with her doctor put pros and cons out in the open.

What Steps Make Sense?

Knowledge gives families more control. Always speak up if a prescription feels risky or confusing. Share info about all over-the-counter creams, sprays, or pills, not just what a doctor writes down. Most importantly, push for follow-up, especially if a child’s symptoms linger or if a pregnant woman notices changes or side effects. Research keeps growing, but the safest path still runs through personalized advice from medical professionals who know your family's story. That approach builds trust and gives everyone the best shot at safe, lasting relief.

Are there any drug interactions with Triamcinolone Acetonide?

Understanding the Risks of Mixing Medicines

People reach for triamcinolone acetonide to treat swelling, itching, or redness tied to skin conditions. It works well for rashes, eczema, and some allergies. Questions about combining this medication with other drugs almost always come up, and with good reason. Mixing steroids with some common prescriptions or over-the-counter products can throw a real wrench in someone’s treatment or trigger unwanted effects.

Why the Talk About Drug Interactions Matters

Doctors and pharmacists talk a lot about drug interactions because they see what happens when things go wrong. Triamcinolone acetonide has mostly local effects when used as a cream or ointment. Once it gets into the bloodstream, though, the issues get more complicated. People using it over large areas or with potent versions (like injections or inhalers) should pay extra close attention.

For example, people using oral or injected forms or steroids—a group that includes triamcinolone—need to watch out for drugs that lower immunity even more. Sure, a one-off skin rash rarely causes trouble, but if your body is already fighting an infection or you’re on medication for your immune system, this can put you in a tough spot. Antibiotics, antifungals, and antivirals don’t always play nicely with steroids. I remember a patient who developed a nasty bout of thrush after combining nasal steroids and a strong antibiotic. Doctors traced it back to the steroid making it harder for the body to control the fungus.

What People Take Alongside Triamcinolone Acetonide

Blood thinners and nonsteroidal anti-inflammatory drugs (NSAIDs) can make bleeding and stomach irritation worse when mixed with steroids. Someone who takes a daily aspirin or warfarin for heart issues should ask specifically about these interactions. A case that stuck with me involved someone getting injections for joint pain—they didn’t mention using blood thinners, and it ended up in an emergency room visit due to unexpected bleeding.

Diabetes medications matter, too. Steroids can bump up blood sugar, and triamcinolone counts as a steroid. For folks keeping their diabetes in check, using a steroid—even on the skin in large amounts—can throw off glucose readings. I once worked with a patient who couldn’t figure out why her sugar spiked. It only made sense after learning she had started an eczema cream.

Vaccines deserve a mention, especially live ones. People on high-dose or long-term steroids don’t mount the same defense to vaccines, and the risk from a live virus vaccine rises. It’s safer to talk with a healthcare provider before getting any shots if you’re using these medicines regularly.

What Can We Do?

Most drug problems boil down to missing information. Sharing every medicine, vitamin, or supplement with a healthcare provider gives the clearest picture. If a new rash treatment gets added to the mix, bring up every other prescription—even the ones that seem unrelated. Read medication leaflets and reach out to pharmacists. They see interactions show up before anyone else. People benefit when the whole care team communicates.

If questions pop up, don’t wait for a warning sign. An odd bruise, rising sugar, slow wound healing, or extra infections can all point to a drug clash. Catching these early saves trouble and leads to better outcomes for everyone.

Triamcinolone Acetonide
Names
Preferred IUPAC name (1R,2R,4S,8S,9S,12S,13S)-16,16-Dimethyl-9-fluoro-2,13,17-trihydroxy-17-(2-hydroxyacetyl)-10,15-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosa-11,14-dien-8-yl acetate
Other names Kenalog
Aristocort
Nasacort
Triesence
Triderm
TAC
Pronunciation /traɪˌæmsɪˈnəʊl ən əˈsiːtəˌnaɪd/
Preferred IUPAC name (1R,2R,4S,8S,9S,11S,12S,13R)-11,17-Dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,18-dien-8-yl acetate
Other names Kenalog
Aristocort
Nasacort
Triderm
TAC
Tri-Nasal
Triesence
Cinalog
Pronunciation /traɪˌæmsɪˈnəʊl ən əˈsiːtəˌnaɪd/
Identifiers
CAS Number 124-94-7
Beilstein Reference 2241077
ChEBI CHEBI:9648
ChEMBL CHEMBL1203
ChemSpider 5036
DrugBank DB00620
ECHA InfoCard 13d2a1ccefe5-46aa-40c7-811d-7a82d49b735a
EC Number 200-948-7
Gmelin Reference 107221
KEGG D01406
MeSH D017101
PubChem CID 5484454
RTECS number PG4955000
UNII BKJ8M8G8AP
UN number UN number not assigned
CAS Number 124-94-7
Beilstein Reference 2811482
ChEBI CHEBI:9648
ChEMBL CHEMBL1206
ChemSpider 247098
DrugBank DB00620
ECHA InfoCard 100.046.747
EC Number 200-945-6
Gmelin Reference 1574883
KEGG D01477
MeSH D014238
PubChem CID C123657
RTECS number RV1750000
UNII 7Z8S9VHY3E
UN number UN2811
Properties
Chemical formula C24H31FO6
Molar mass 434.49 g/mol
Appearance White to cream-colored crystalline powder
Odor Odorless
Density 1.31 g/cm³
Solubility in water Practically insoluble in water
log P 1.99
Vapor pressure <0.0000001 mmHg (25°C)
Acidity (pKa) 12.42
Basicity (pKb) 13.63
Magnetic susceptibility (χ) -9.2e-6
Refractive index (nD) 1.523
Viscosity Viscous
Dipole moment 1.82 D
Chemical formula C24H31FO6
Molar mass 434.49 g/mol
Appearance White to off-white crystalline powder
Odor Odorless
Density 1.29 g/cm³
Solubility in water Practically insoluble in water
log P 1.97
Acidity (pKa) 12.23
Basicity (pKb) 12.23
Magnetic susceptibility (χ) -7.6e-6
Refractive index (nD) 1.553
Dipole moment 1.935 D
Thermochemistry
Std molar entropy (S⦵298) 761.3 J·mol⁻¹·K⁻¹
Std molar entropy (S⦵298) Std molar entropy (S⦵298) of Triamcinolone Acetonide is 665 J·mol⁻¹·K⁻¹
Pharmacology
ATC code D07AB09
ATC code D07AC09
Hazards
Main hazards May cause eye irritation.
GHS labelling Not a hazardous substance or mixture according to the Globally Harmonized System (GHS).
Pictograms Triamcinolone Acetonide" pictograms: `GHS07`
Signal word No signal word
Hazard statements Hazard statements: Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Precautionary statements Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin unless directed by your doctor. Discontinue use if irritation develops. Use only as directed by your physician.
NFPA 704 (fire diamond) 1-1-0
Flash point > 285.5 °C
Lethal dose or concentration Lethal dose or concentration: "LD50 (oral, rat): 1450 mg/kg
LD50 (median dose) 1867 mg/kg (rat, oral)
PEL (Permissible) Not established
REL (Recommended) 0.1%
Main hazards Causes eye irritation; may cause skin irritation; harmful if swallowed
GHS labelling GHS labelling of Triamcinolone Acetonide: `"Not a hazardous substance or mixture according to the Globally Harmonized System (GHS)"`
Pictograms eye irritation, skin irritation, pregnancy, breastfeeding, children, elderly
Signal word No signal word
Hazard statements May cause damage to organs through prolonged or repeated exposure.
Precautionary statements Keep out of reach of children. For external use only. Avoid contact with eyes. Do not use on broken or infected skin unless directed by a doctor. Discontinue use if irritation or sensitivity develops. Use only as directed by your physician.
NFPA 704 (fire diamond) NFPA 704: 1-1-0
Flash point > 265 °C
Lethal dose or concentration Rat oral LD50: >3000 mg/kg
LD50 (median dose) > 1863 mg/kg (Rat, oral)
NIOSH SAF8750
PEL (Permissible) Not established
REL (Recommended) Triamcinolone Acetonide 0.1% Cream
Related compounds
Related compounds Triamcinolone
Triamcinolone benetonide
Triamcinolone hexacetonide
Triamcinolone furetonide
Related compounds Triamcinolone
Fluocinolone acetonide
Dexamethasone
Betamethasone
Prednisolone