This compound belongs to the family of synthetic progestins, structured as a derivative of progesterone. Chemists recognize it by its molecular formula, C24H29Cl2O4. On paper, the structure sports a chloromethyl group at the first carbon, a chlorine atom at the sixth, and an acetoxy group at the seventeenth. These modifications impact both pharmacological activity and physical behavior. This molecule plays a role as a raw material in pharmaceuticals, for instance during the synthesis of advanced corticosteroids or investigational hormones. HS Code placement falls within the chemical raw materials class, more specifically under substances for pharmaceutical use, which customs authorities track for reasons of tariff and safety.
Many lab technicians and formulators encounter this compound as a white to off-white crystalline powder, sometimes seen as small flakes, soft pearls, or even microscopic solids, all depending on the exact process conditions and purification steps. It rarely comes as a liquid at room temperature—crystals or powder dominate the commercial inventory. Under correct storage, this substance remains stable if kept in air-tight containers, shielded from direct sunlight, and maintained at temperatures not exceeding room standards. Density measurements hover around typical steroid ranges, with values close to 1.2–1.3 g/cm3, according to supplier specifications. It usually dissolves sparingly in water but mixes more readily with organic solvents such as ethanol, chloroform, and acetone—solubility matters when choosing how to handle and measure it during formulation. Material safety data points out that this compound can produce dust, and care should be taken to avoid inhalation, especially during milling or weighing operations.
From my own experience handling chemicals with similar backbones, gloves and goggles come out before the jar ever opens. Many halogenated progesterone derivatives irritate mucous membranes, and some can trigger skin sensitivities with regular exposure. This substance stands no exception—its molecular structure, specifically the chloromethyl and acetoxy groups, boost lipophilicity as well as reactivity. Laboratories treat it as hazardous, sometimes harmful on both acute and chronic exposure. Chemical stability does not equal harmlessness: under basic or strong acidic conditions, decomposition may produce noxious byproducts, notably chlorinated organics. Fire marshals and EHS officers insist on segregating such compounds from oxidizers and moisture-rich environments, and bench chemists often rely on spill trays and dedicated waste bins. Long-term storage decisions should always account for hydrolytic sensitivity, especially since the acetoxy function can react over time.
Producers and distributors attach detailed specification sheets for each batch, listing not just purity but residual solvents, traces of related impurities, melting point—often in the range of 156–160°C—and water content, which should stay close to nil. Some shipments arrive vacuum-sealed, sometimes under nitrogen, which cuts back on oxidation and accidental moisture introduction. As with many pharmaceutical intermediates, handling guidelines include not eating, drinking, or smoking in the processing area, and having a ready supply of running water in case of personal contamination. Any laboratory solution or dilution should use glassware, since certain plastics may interact poorly with organic solvents carrying this compound. In my work, following these simple rules prevents headaches down the road—fewer spills, less clean-up, and far fewer close calls with the safety team.
In the broader pharmaceutical ecosystem, 1-Chloromethyl-6-Chloro-6-Dehydro-17A-Acetoxy Progesterone counts as a high-purity raw material for advanced synthesis. Regulatory bodies demand full traceability: batch numbers, COA files, and clear labeling, not just for legality’s sake but for downstream drug safety. Import and export get tied to proper HS Codes, and shippers come prepared for customs queries about hazardous labeling and UN packaging categories. For any manufacturer, ensuring continuity of this intermediate’s quality and identity protects both intellectual property and public trust.
On the technical side, researchers now push for greener methods, swapping out heavy halogenated solvents for safer options and refining crystallization steps to cut both energy use and waste. Establishing clear waste segregation streams, encouraging the shift toward semi-automated weighing, and keeping up-to-date with EHS guidelines shows that sustainable handling is more than talk—it means lower risk, better compliance, and more resilient supply lines. As regulatory standards rise, companies investing in full documentation, transparent safety data, and proactive staff training put themselves in a better place to handle both routine inspections and emergency incidents. With every kilogram produced, moved, or stored, understanding the details—from crystal form to hazard codes—shapes both personal safety and commercial success.
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