Penfluridol draws attention for its distinctive profile as a long-acting antipsychotic agent. The molecule belongs to the diphenylbutylpiperidine class, featuring a rather complex molecular arrangement. In terms of chemical structure, Penfluridol boasts a formula of C28H27ClF5NO, integrating chlorine, fluorine, and other functional groups that influence its stability and appearance. The substance presents as a white, crystalline solid, which makes handling and storage relatively straightforward for those involved in raw material sourcing.
Diving deeper into its physical makeup, Penfluridol weighs about 523.97 g/mol, reflecting a dense arrangement of heavy atoms and several fluorine groups. Crystal structure points toward a solid at room temperature, which can be processed further into flakes, powder, or pearl-like forms depending on manufacturing methods. Visual inspection uncovers a fine crystalline solid that does not clump easily, offering reliable dosing and measurement in industrial settings. In solution, Penfluridol will dissolve slowly in alcohols and organic solvents due to its bulky structure, while remaining nearly insoluble in water. This insolubility stems from its pronounced hydrophobic character, which both protects it from humidity and makes waste management during manufacturing demanding.
Penfluridol ships under HS Code 2933.39, which applies to heterocyclic compounds with nitrogen hetero-atoms. Standard batches register a purity of at least 98%, minimizing unwanted side reactions in pharmaceutical synthesis. Density checks out at roughly 1.3 g/cm³, based on lab measurement and supplier certificates of analysis. Physical appearances run from finely milled powder to larger flaky crystals, depending on grinding and processing post-synthesis. Pearl and granular forms appear in some suppliers’ catalogs for those with specialized blending equipment. Solutions typically arrive in measured liters, dissolved in ethanol or DMSO, allowing researchers workable volumes for chemical studies.
Working with Penfluridol means paying close attention to chemical safety. Labeling flags it as both hazardous and potentially harmful, especially with chronic exposure. The molecule's hydrophobic and aromatic nature means it resists breakdown and can linger on surfaces or in the body. Safety Data Sheets advise use of full protective equipment, including gloves, safety goggles, and lab coats, due to skin and eye irritation risks. Inhalation of dust presents a separate risk, with particulate controls essential in any industrial environment. Proper ventilation pulls airborne dust away from personnel, while sealed containers restrict accidental spills or leaks during storage. From experience in pharmaceutical warehouses, careful segregation from incompatible chemicals such as strong acids or oxidizers greatly reduces the chances of an unexpected reaction.
Most Penfluridol in the supply chain finds its way toward formulation and research applications. Its physical resilience means it holds up well during transport, but shipment in cool, dry conditions keeps the crystals from degrading or clumping. Chemists preparing injection or tablet formulations rely on the substance’s predictable density and solubility profile for efficient scaling. As one who has worked with material procurement teams, choosing Penfluridol from reputable sources is critical: certificates should specify both molecular formula confirmation and impurity profiles. Any deviation in density or melting point (typically registering between 172-175°C) signals possible mix-ups with lookalike chemicals, which has real safety consequences.
Safe use of Penfluridol calls for training and risk assessments. Long-term health monitoring for handlers, improvements in local exhaust ventilation, and closed-loop systems during synthesis lead to safer outcomes for workers. Proper labeling and secondary containment keep spills or leaks from spreading. Waste disposal must follow hazardous chemical guidelines, with incineration preferred over landfill dumping, protecting both workers and the environment. Supplying safety goggles and gloves directly at workstations, rather than locked storage, increases actual compliance. Posting up-to-date chemical hazard charts in break rooms and supply areas keeps risks top of mind for those less familiar with industrial chemicals.
Penfluridol’s reliability doesn't rest just on purity. Sourcing checks require attention to certificates of analysis, origin records, and batch traceability. Occasional verification through third-party labs gives suppliers the nudge to maintain high standards. Raw material buyers should insist on specific storage and transport conditions being spelled out in contracts. Regular inspection of packaging integrity and in-house assays to check residual solvents or degradation products supports ongoing quality. Industry veterans know that transparency in documentation is the best defense against lapses that threaten both business integrity and product safety.
| Property | Data |
|---|---|
| Chemical Name | Penfluridol |
| Molecular Formula | C28H27ClF5NO |
| Molecular Weight | 523.97 g/mol |
| Physical Form | White solid, crystalline, powder, flakes, pearls |
| Density | 1.3 g/cm³ |
| Melting Point | 172-175°C |
| Solubility | Alcohols, organic solvents; insoluble in water |
| HS Code | 2933.39 |
| Hazard | Harmful, hazardous, irritant |
No amount of technical data replaces real experience in a chemical warehouse or laboratory. Reading labels, checking documentation, and direct observation of physical properties keeps surprises to a minimum. Seasonal shifts in temperature and humidity demand extra vigilance—crystals that flow easily in winter might cake up in a humid storeroom by midsummer. Close, ongoing dialog between suppliers and buyers, with a focus on transparency about every physical and chemical attribute, creates stronger supply chains. Many issues, like unexpected impurities or off-specification melting points, come from gaps in communication and missed inspection steps. Stepping through these requirements, again and again, makes handling hazardous raw materials less about luck and more about proven routine.
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